Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota

show annotations for term's descendants           Sort by:
apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 part_of IEA
PMID:17483091 GO_REF:0000002 GO_REF:0000107 RGD:2325744 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
JBrowse link
G CASP9 caspase 9 part_of IEA Ensembl GO_REF:0000107 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,515...74,730,092
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr 1:168,353,655...168,453,175
Ensembl chr 1:168,350,557...168,530,087
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16921
    protein-containing complex 4985
      apoptosome 3
Path 2
Term Annotations click to browse term
  cellular_component 16921
    cellular anatomical entity 16792
      intracellular anatomical structure 12609
        cytoplasm 9856
          cytosol 3466
            apoptosome 3
paths to the root