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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota

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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 part_of ISO MGI
PMID:17483091 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:2325744 NCBI chr10:90,989,311...91,082,743
Ensembl chr10:90,989,311...91,082,770
JBrowse link
G Casp9 caspase 9 part_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats part_of IDA (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr 9:60,793,206...60,880,431
Ensembl chr 9:60,794,542...60,880,370
JBrowse link

Term paths to the root
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  cellular_component 28363
    protein-containing complex 5516
      apoptosome 3
Path 2
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  cellular_component 28363
    cellular anatomical entity 19018
      intracellular anatomical structure 14164
        cytoplasm 11389
          cytosol 3778
            apoptosome 3
paths to the root