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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptosome
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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 part_of IDA
TAS
ISO
(PMID:21827945)
(PMID:18309324)
UniProt
RGD
PMID:17483091 PMID:18309324 PMID:21827945 RGD:2325744 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
JBrowse link
G CASP9 caspase 9 part_of IDA (PMID:21827945) UniProt PMID:21827945 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr15:70,654,554...70,778,823
Ensembl chr15:70,654,554...70,763,558
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19349
    protein-containing complex 5900
      apoptosome 3
Path 2
Term Annotations click to browse term
  cellular_component 19349
    cellular anatomical entity 19121
      intracellular anatomical structure 15249
        cytoplasm 12330
          cytosol 5495
            apoptosome 3
paths to the root