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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptosome
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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 part_of IEA
ISO
Ensembl
InterPro
RGD
PMID:17483091 GO_REF:0000002 GO_REF:0000107 RGD:2325744 NCBI chr15:38,026,893...38,160,842
Ensembl chr15:38,028,132...38,114,987
JBrowse link
G CASP9 caspase 9 part_of IEA Ensembl GO_REF:0000107 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr30:34,376,072...34,467,278
Ensembl chr30:34,376,077...34,467,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16542
    protein-containing complex 5164
      apoptosome 3
Path 2
Term Annotations click to browse term
  cellular_component 16542
    cellular anatomical entity 16406
      intracellular anatomical structure 12774
        cytoplasm 9964
          cytosol 3529
            apoptosome 3
paths to the root