Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota

GViewer not supported for chinchilla.
show annotations for term's descendants           Sort by:
apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 part_of ISO (PMID:21827945)
PMID:17483091 PMID:21827945 PMID:26265044 RGD:11079191 RGD:2325744 NCBI chrNW_004955405:34,619,780...34,693,616
Ensembl chrNW_004955405:34,623,267...34,693,677
JBrowse link
G Casp9 caspase 9 part_of ISO (PMID:21827945) UniProt PMID:21827945 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chrNW_004955450:6,122,271...6,195,345
Ensembl chrNW_004955450:6,122,439...6,197,177
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12116
    protein-containing complex 3855
      apoptosome 3
Path 2
Term Annotations click to browse term
  cellular_component 12116
    cellular anatomical entity 11974
      intracellular anatomical structure 10289
        cytoplasm 8010
          cytosol 2964
            apoptosome 3
paths to the root