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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota

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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 part_of ISO PMID:26265044
PMID:17483091 PMID:21827945 PMID:26265044 RGD:11079191 RGD:2325744 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939
JBrowse link
G CASP9 caspase 9 part_of ISO (PMID:21827945) UniProt PMID:21827945 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr15:49,607,308...49,711,188
Ensembl chr15:68,375,939...68,477,395
JBrowse link

Term paths to the root
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  cellular_component 12767
    protein-containing complex 3970
      apoptosome 3
Path 2
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  cellular_component 12767
    cellular anatomical entity 12614
      intracellular anatomical structure 10773
        cytoplasm 8363
          cytosol 3087
            apoptosome 3
paths to the root