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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptosome
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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


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apoptosome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:2325744
RGD:1624291
RGD:11079191
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:1624291
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats JBrowse link 8 65,686,586 65,774,940 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20300
    protein-containing complex 6094
      apoptosome 3
Path 2
Term Annotations click to browse term
  cellular_component 20300
    intracellular 14243
      cytoplasm 11099
        cytosol 4143
          apoptosome 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.