Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:telomere maintenance in response to DNA damage
go back to main search page
Accession:GO:0043247 term browser browse the term
Definition:Any process that occur in response to the presence of critically short or damaged telomeres.
Synonyms:exact_synonym: DNA damage response, telomere maintenance


show annotations for term's descendants           Sort by:
telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in ISO (PMID:28216226) RGD PMID:28216226 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Nbn nibrin involved_in ISS
ISO		 GO_REF:0000024
(MGI:6269043|PMID:28216226)
(PMID:28216226)		 UniProt
RGD		 PMID:28216226 GO_REF:0000024 MGI:6269043 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha involved_in ISO (PMID:28216226) RGD PMID:28216226 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:15583028) RGD PMID:15583028 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
positive regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl6a actin-like 6A involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401 		JBrowse link
G Actr5 actin related protein 5 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 3:147,282,461...147,295,870
Ensembl chr 3:147,282,624...147,296,110 		JBrowse link
G Actr8 actin related protein 8 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr16:5,164,131...5,186,353
Ensembl chr16:5,164,129...5,178,577 		JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911 		JBrowse link
G Ino80b INO80 complex subunit B involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456 		JBrowse link
G Ino80c INO80 complex subunit C involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403 		JBrowse link
G Ino80d INO80 complex subunit D involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 9:64,447,075...64,514,013
Ensembl chr 9:64,457,165...64,515,242 		JBrowse link
G Ino80e INO80 complex subunit E involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469 		JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G Tfpt TCF3 fusion partner involved_in IEA
ISO		 GO_REF:0000107
(MGI:5638510|PMID:23979016)		 Ensembl
RGD		 PMID:23979016 GO_REF:0000107 MGI:5638510 NCBI chr 1:65,587,633...65,597,407
Ensembl chr 1:65,582,359...65,611,689 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (MGI:5638510|PMID:23979016) RGD PMID:23979016 MGI:5638510 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IEA		 (MGI:3829120|PMID:18185984)
GO_REF:0000107		 RGD
Ensembl		 PMID:18185984 GO_REF:0000107 MGI:3829120 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Dclre1b DNA cross-link repair 1B involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4462732|PMID:20551906), (MGI:4830207|PMID:20619712)
GO_REF:0000024
(PMID:16730175), (PMID:20479256)		 Ensembl
RGD
UniProt		 PMID:16730175 PMID:20479256 PMID:20551906 PMID:20619712 GO_REF:0000024 GO_REF:0000107 MGI:4462732 MGI:4830207 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Nbn nibrin involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6269043|PMID:28216226)
(PMID:28216226)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:28216226 GO_REF:0000024 GO_REF:0000107 MGI:6269043 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 ComplexPortal:CPX-1993 (PMID:14690602), (PMID:17499040), (PMID:24095731)
MGI:3619525 (PMID:15968270)
GO_REF:0000033
(MGI:4830207|PMID:20619712), (MGI:5883205|PMID:24120135)		 RGD
GO_Central		 PMID:14690602 PMID:15968270 PMID:17499040 PMID:20619712 PMID:24095731 More... GO_REF:0000033 MGI:4830207 MGI:5883205 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Terf2ip TERF2 interacting protein NOT|involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:4440768|PMID:20339076), (MGI:4839412|PMID:20622869)		 UniProt
GO_Central
RGD		 PMID:20339076 PMID:20622869 GO_REF:0000024 GO_REF:0000033 MGI:4440768 MGI:4839412 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064 		JBrowse link
telomere maintenance via base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISO
IEA		 (PMID:24703901)
GO_REF:0000107		 RGD
Ensembl		 PMID:24703901 GO_REF:0000107 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular response to stimulus 9075
        cellular response to stress 2061
          DNA damage response 891
            telomere maintenance in response to DNA damage 30
              negative regulation of telomere maintenance in response to DNA damage + 5
              positive regulation of telomere maintenance in response to DNA damage + 15
              protection from non-homologous end joining at telomere + 10
              regulation of telomere maintenance in response to DNA damage + 20
              telomere maintenance via base-excision repair 1
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular component organization or biogenesis 7290
        cellular component organization 6980
          organelle organization 3887
            chromosome organization 583
              telomere organization 149
                telomere maintenance 144
                  telomere maintenance in response to DNA damage 30
                    negative regulation of telomere maintenance in response to DNA damage + 5
                    positive regulation of telomere maintenance in response to DNA damage + 15
                    protection from non-homologous end joining at telomere + 10
                    regulation of telomere maintenance in response to DNA damage + 20
                    telomere maintenance via base-excision repair 1
paths to the root