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Term:Fanconi anaemia nuclear complex
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Accession:GO:0043240 term browser browse the term
Definition:A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
Synonyms:exact_synonym: FA complex;   FA core complex;   FA nuclear complex;   Fanconi anaemia complex

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Fanconi anaemia nuclear complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07030926.1 RGD:13792537
G Cenps centromere protein S JBrowse link 5 165,946,106 165,955,723 RGD:1624291
G Cenpx centromere protein X JBrowse link 10 109,890,904 109,893,804 RGD:1624291
G Cort cortistatin JBrowse link 5 165,942,780 165,944,221 RGD:13792537
G Faap100 FA core complex associated protein 100 JBrowse link 10 109,539,381 109,552,434 RGD:1600115
G Faap20 FA core complex associated protein 20 JBrowse link 5 172,648,171 172,655,576 RGD:1600115
G Faap24 FA core complex associated protein 24 JBrowse link 1 91,657,263 91,663,485 RGD:1624291
G Fanca FA complementation group A JBrowse link 19 56,067,548 56,126,075 RGD:1624291
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
G Fancc FA complementation group C JBrowse link 17 826,512 955,703 RGD:1600115
G Fance FA complementation group E JBrowse link 20 7,888,927 7,906,142 RGD:1624291
G Fancf FA complementation group F JBrowse link 1 107,229,516 107,232,321 RGD:1624291
G Fancg FA complementation group G JBrowse link 5 58,448,060 58,456,416 RGD:1624291
G Fancl FA complementation group L JBrowse link 14 110,675,306 110,740,880 RGD:1624291
G Fancm FA complementation group M JBrowse link 6 86,823,195 86,877,067 RGD:1624291

Term paths to the root
Path 1
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  cellular_component 20300
    protein-containing complex 6095
      Fanconi anaemia nuclear complex 15
Path 2
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  cellular_component 20300
    cellular anatomical entity 19956
      organelle 12977
        intracellular organelle 12441
          intracellular membrane-bounded organelle 10250
            nucleus 6971
              nuclear lumen 4051
                nucleoplasm 3398
                  Fanconi anaemia nuclear complex 15
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.