Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasmic SCF ubiquitin ligase complex
go back to main search page
Accession:GO:0043223 term browser browse the term
Definition:A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
Synonyms:exact_synonym: cytoplasmic SCF complex;   cytoplasmic Skp1/Cul1/F-box protein complex;   cytoplasmic cullin complex


show annotations for term's descendants           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      cytoplasm 11456
        cytoplasmic ubiquitin ligase complex 30
          cytoplasmic SCF ubiquitin ligase complex 0
Path 2
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      catalytic complex 1487
        transferase complex 818
          ubiquitin ligase complex 309
            cullin-RING ubiquitin ligase complex 171
              SCF ubiquitin ligase complex 70
                cytoplasmic SCF ubiquitin ligase complex 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.