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ONTOLOGY REPORT - ANNOTATIONS

Term:myelin maintenance
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Accession:GO:0043217 term browser browse the term
Definition:The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.


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myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (MGI:2176408|PMID:11875044), (MGI:3513562|PMID:15489218) RGD PMID:11875044 PMID:15489218 MGI:2176408 MGI:3513562 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3513562|PMID:15489218)		 UniProt
RGD		 PMID:15489218 GO_REF:0000024 MGI:3513562 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO (MGI:4458974|PMID:20534485) RGD PMID:20534485 MGI:4458974 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 involved_in ISO
ISS		 (PMID:30620337), (PMID:30620338)
GO_REF:0000024		 RGD
UniProt		 PMID:30620337 PMID:30620338 GO_REF:0000024 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 involved_in ISO (MGI:5296417|PMID:21966409) RGD PMID:21966409 MGI:5296417 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
central nervous system myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in ISO
ISS
IEA		 (PMID:21543606)
GO_REF:0000024
GO_REF:0000107		 RGD
Alzheimers_University_of_Toronto
Ensembl		 PMID:21543606 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO MGI:3829000|MGI:4430585 (MGI:3826747|PMID:18815260), (MGI:4950761|PMID:21491498) RGD PMID:18815260 PMID:21491498 MGI:3826747 MGI:4950761 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Myrf myelin regulatory factor involved_in IBA
ISO		 PMID:21873635
(MGI:5437779|PMID:22956843)		 RGD PMID:22956843 PMID:21873635 MGI:5437779, RGD:13792537 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3772418|PMID:18082964) RGD PMID:18082964 MGI:3772418 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
peripheral nervous system myelin maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 acts_upstream_of_or_within ISO (MGI:4454957|PMID:20448149) RGD PMID:20448149 MGI:4454957 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Fa2h fatty acid 2-hydroxylase acts_upstream_of_or_within ISO MGI:3829000 (MGI:3826747|PMID:18815260) RGD PMID:18815260 MGI:3826747 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in IEA
ISO		 GO_REF:0000002
GO_REF:0000107
(MGI:3041895|PMID:15082788)		 InterPro
Ensembl
RGD		 PMID:15082788 GO_REF:0000002 GO_REF:0000107 MGI:3041895 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member involved_in ISO (MGI:4441217|PMID:20237282) RGD PMID:20237282 MGI:4441217 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Plec plectin involved_in ISO MGI:3721885 (MGI:5502798|PMID:23836526) RGD PMID:23836526 MGI:5502798 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Prx periaxin involved_in IBA
ISO		 PMID:21873635
(MGI:1859096|PMID:10839370)		 RGD PMID:10839370 PMID:21873635 MGI:1859096, RGD:13792537 NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:82,786,815...82,807,407 		JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 acts_upstream_of_or_within ISO MGI:4367025 (MGI:4366127|PMID:19805030) RGD PMID:19805030 MGI:4366127 NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857872 (MGI:1344528|PMID:10433959)		 UniProt
RGD		 PMID:10433959 GO_REF:0000024 MGI:1344528 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      ensheathment of neurons 179
        axon ensheathment 179
          myelination 177
            myelin maintenance 17
              central nervous system myelin maintenance 4
              peripheral nervous system myelin maintenance 9
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        multicellular organism development 5440
          system development 4941
            nervous system development 2769
              ensheathment of neurons 179
                axon ensheathment 179
                  myelination 177
                    myelin maintenance 17
                      central nervous system myelin maintenance 4
                      peripheral nervous system myelin maintenance 9
paths to the root