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ONTOLOGY REPORT - ANNOTATIONS

Term:amine binding
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Accession:GO:0043176 term browser browse the term
Definition:Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.

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amine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IPI RGD PMID:6289140 RGD:2301944 NCBI chr 1:255,772,217...255,773,617 JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IDA gamma-aminobutyraldehyde RGD PMID:10467734 RGD:2313412 NCBI chr13:79,505,738...79,522,539 JBrowse link
G Hmbs hydroxymethylbilane synthase IPI substrate (porphobilinogen) binding RGD PMID:9344466 RGD:2301695 NCBI chr 8:44,673,554...44,680,950 JBrowse link
G Orm1 orosomucoid 1 part_of IDA RGD PMID:3252025 RGD:2316648 NCBI chr 5:76,766,637...76,776,149 JBrowse link
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A enables ISO (PMID:19057895) RGD PMID:19057895 NCBI chr15:49,950,035...50,022,188 JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C enables ISO (PMID:19057895) RGD PMID:19057895 NCBI chr  X:110,640,777...110,870,288 JBrowse link
serotonin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A enables IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:8271204, PMID:21873635 RGD:2303617, RGD:13792537 NCBI chr 2:36,694,174...36,695,442 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B enables IBA
ISO		 PMID:21873635
(MGI:4821070|PMID:17325130)		 RGD PMID:17325130, PMID:21873635 MGI:4821070, RGD:13792537 NCBI chr 8:82,513,572...82,534,892 JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D enables IBA
ISO		 PMID:21873635
(MGI:48584|PMID:1557407)		 RGD PMID:1557407, PMID:21873635 MGI:48584, RGD:13792537 NCBI chr 5:148,655,979...148,676,534 JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F enables IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:8380639)		 Ensembl
RGD		 PMID:8380639, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr11:2,642,751...2,644,150 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A enables ISO (PMID:15862800)
(PMID:15831837), (PMID:15862800), (PMID:18703043), (PMID:19057895), (PMID:7582481)		 RGD PMID:7582481 PMID:15831837 PMID:15862800 PMID:18703043 PMID:19057895 NCBI chr15:49,950,035...50,022,188 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B enables IDA
ISO
ISS
IEA		 (PMID:12970106), (PMID:15625277), (PMID:15831837), (PMID:15862800), (PMID:17609583), (PMID:18703043), (PMID:19057895), (PMID:19307114), (PMID:7582481), (PMID:7926008)
(MGI:4821070|PMID:17325130)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:7582481 PMID:7926008 PMID:12970106 PMID:15625277 PMID:15831837 PMID:15862800 PMID:17325130 PMID:17609583 PMID:18703043 PMID:19057895 PMID:19307114, PMID:1505525 GO_REF:0000024 GO_REF:0000107 MGI:4821070, RGD:61633 NCBI chr 9:86,735,793...86,756,640 JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C enables ISO (PMID:12970106), (PMID:15831837), (PMID:18703043), (PMID:19057895), (PMID:7582481) RGD PMID:7582481 PMID:12970106 PMID:15831837 PMID:18703043 PMID:19057895 NCBI chr  X:110,640,777...110,870,288 JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A enables ISO (PMID:7565620) RGD PMID:7565620 NCBI chr 8:49,242,018...49,254,475 JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:55,765,981...55,949,921 JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:7,444,968...7,454,651 JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:32,686,911...32,699,835 JBrowse link
G Maoa monoamine oxidase A IDA
IMP		 Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741, PMID:11754741, PMID:11263670 RGD:1600709, RGD:1600709, RGD:1600713 NCBI chr  X:6,032,172...6,098,308 JBrowse link
G Slc6a4 solute carrier family 6 member 4 enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:61,824,208...61,858,924 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19980
    binding 17008
      amine binding 17
        1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding 2
        phenylalkylamine binding 0
        serotonin binding 13
paths to the root