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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
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Accession:GO:0043162 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
Synonyms:exact_synonym: ubiquitin-dependent protein breakdown via the multivesicular body pathway;   ubiquitin-dependent protein catabolic process via the MVB pathway;   ubiquitin-dependent protein catabolism via the MVB pathway;   ubiquitin-dependent protein degradation via the multivesicular body pathway


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ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 30 21,123,333 21,229,907 RGD:13508589
G PLAA phospholipase A2 activating protein JBrowse link 11 45,121,423 45,159,093 RGD:13508589
G PTPN23 protein tyrosine phosphatase non-receptor type 23 JBrowse link 20 41,485,959 41,511,250 RGD:13508589
G TSG101 tumor susceptibility 101 JBrowse link 21 40,910,870 40,952,922 RGD:13508589
G UBAP1 ubiquitin associated protein 1 JBrowse link 11 50,890,090 50,974,901 RGD:13508589
G UBAP1L ubiquitin associated protein 1 like JBrowse link 30 29,475,289 29,496,148 RGD:13508589
G VPS37A VPS37A subunit of ESCRT-I JBrowse link 16 40,571,892 40,624,359 RGD:13508589
G VPS37C VPS37C subunit of ESCRT-I JBrowse link 18 55,204,918 55,212,902 RGD:13508589
G VPS37D VPS37D subunit of ESCRT-I JBrowse link 6 6,602,905 6,606,781 RGD:13508589
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 1 13,638,965 13,673,295 RGD:13508589
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNF8 SNF8 subunit of ESCRT-II JBrowse link 9 25,151,992 25,162,105 RGD:13508589
G VPS28 VPS28 subunit of ESCRT-I JBrowse link 13 37,841,524 37,845,954 RGD:13508589
G VPS36 vacuolar protein sorting 36 homolog JBrowse link 25 150,984 191,531 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13644
    metabolic process 8513
      catabolic process 1632
        cellular catabolic process 1399
          cellular macromolecule catabolic process 785
            modification-dependent macromolecule catabolic process 488
              modification-dependent protein catabolic process 478
                ubiquitin-dependent protein catabolic process 468
                  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 13
                    protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 3
Path 2
Term Annotations click to browse term
  biological_process 13644
    metabolic process 8513
      catabolic process 1632
        organic substance catabolic process 1382
          macromolecule catabolic process 911
            cellular macromolecule catabolic process 785
              cellular protein catabolic process 582
                proteolysis involved in cellular protein catabolic process 553
                  modification-dependent protein catabolic process 478
                    ubiquitin-dependent protein catabolic process 468
                      ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 13
                        protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.