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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
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Accession:GO:0043154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
Synonyms:exact_synonym: down regulation of caspase activity;   downregulation of caspase activity;   negative regulation of caspase activation
 narrow_synonym: inhibition of caspase activation;   inhibition of caspase activity
 broad_synonym: negative regulation of caspase activity
 alt_id: GO:0001719


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negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chr 1:113,359,038...113,407,119
Ensembl chr 1:113,359,575...113,407,131 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:21874357 RGD:150540304 NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790 		JBrowse link
G HSP70 heat shock protein 70 ISO reduced cleavage of Casp8 and Casp9 in brain following hypoxic/ischemic injury RGD PMID:16397188 RGD:1626654 NCBI chr12:1,285,282...1,287,670 JBrowse link
G IL6 interleukin 6 ISO RGD PMID:19061939 RGD:2306937 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chr 6:7,247,780...7,316,282
Ensembl chr 6:7,263,574...7,316,297 		JBrowse link
G PTMA prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chr25:43,563,145...43,567,987
Ensembl chr25:43,562,395...43,675,699 		JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      negative regulation of cellular process 5391
        negative regulation of programmed cell death 1051
          negative regulation of apoptotic process 1007
            negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 12
              inhibition of cysteine-type endopeptidase activity involved in apoptotic process 0
              negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 0
              negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 0
Path 2
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      organic substance metabolic process 10554
        macromolecule metabolic process 8924
          protein metabolic process 4325
            proteolysis 1473
              regulation of proteolysis 413
                regulation of peptidase activity 36
                  regulation of endopeptidase activity 36
                    regulation of cysteine-type endopeptidase activity 30
                      regulation of cysteine-type endopeptidase activity involved in apoptotic process 27
                        negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 12
                          inhibition of cysteine-type endopeptidase activity involved in apoptotic process 0
                          negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 0
                          negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 0
paths to the root