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Term:positive regulation of I-kappaB kinase/NF-kappaB signaling
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Accession:GO:0043123 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
Synonyms:narrow_synonym: stimulation of I-kappaB kinase/NF-kappaB cascade
 related_synonym: activation of I-kappaB kinase/NF-kappaB cascade;   positive regulation of I-kappaB kinase/NF-kappaB cascade;   up regulation of I-kappaB kinase/NF-kappaB cascade;   upregulation of I-kappaB kinase/NF-kappaB cascade


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positive regulation of I-kappaB kinase/NF-kappaB signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 13 74,154,533 74,333,244 RGD:1624291
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1600115
RGD:1624291
G Ajuba ajuba LIM protein JBrowse link 15 33,208,210 33,218,456 RGD:1624291
RGD:1600115
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:11059571
RGD:1600115
RGD:1624291
G Alpk1 alpha-kinase 1 JBrowse link 2 231,997,360 232,117,471 RGD:1600115
RGD:1624291
G Ankrd17 ankyrin repeat domain 17 JBrowse link 14 19,291,025 19,431,521 RGD:1624291
RGD:1600115
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 JBrowse link 8 113,953,959 114,039,965 RGD:1600115
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:1624291
RGD:1600115
G Brd4 bromodomain containing 4 JBrowse link 7 14,222,101 14,303,055 RGD:1624291
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:1624291
G Card9 caspase recruitment domain family, member 9 JBrowse link 3 3,798,346 3,806,841 RGD:1624291
RGD:1600115
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:1600115
RGD:1624291
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:1624291
RGD:1600115
G Ccdc22 coiled-coil domain containing 22 JBrowse link X 15,742,978 15,754,925 RGD:1624291
RGD:1600115
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
RGD:1600115
G Ccl21 C-C motif chemokine ligand 21 JBrowse link 5 58,197,678 58,198,782 RGD:1624291
RGD:1600115
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:1624291
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
RGD:1600115
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:1624291
RGD:1600115
G Chuk conserved helix-loop-helix ubiquitous kinase JBrowse link 1 263,848,829 263,884,354 RGD:1624291
RGD:1600115
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:13673777
G Ddx1 DEAD-box helicase 1 JBrowse link 6 38,422,892 38,453,762 RGD:1600115
RGD:1624291
G Ddx21 DExD-box helicase 21 JBrowse link 20 32,213,147 32,232,632 RGD:1600115
RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Eda ectodysplasin-A JBrowse link X 69,730,123 70,222,693 RGD:1624291
RGD:1600115
G Eda2r ectodysplasin A2 receptor JBrowse link X 66,560,200 66,602,509 RGD:13792537
G Edar ectodysplasin-A receptor JBrowse link 20 28,179,132 28,263,092 RGD:13792537
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1600115
RGD:1624291
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:1624291
RGD:1600115
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:1624291
RGD:1600115
G Gprc5b G protein-coupled receptor, class C, group 5, member B JBrowse link 1 188,688,743 188,713,724 RGD:1624291
RGD:13792537
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:1600115
RGD:1624291
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon JBrowse link 13 48,031,325 48,056,394 RGD:1624291
RGD:1600115
G Ikbkg inhibitor of nuclear factor kappa B kinase subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:1624291
RGD:13792537
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:1358666
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1358666
RGD:13792537
RGD:1600115
RGD:1624291
G Il1f10 interleukin 1 family member 10 JBrowse link 3 1,408,560 1,416,601 RGD:13792537
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:13792537
G Il36a interleukin 36, alpha JBrowse link 3 1,330,790 1,335,811 RGD:13792537
G Il36b interleukin 36, beta JBrowse link 3 1,366,123 1,464,851 RGD:13792537
G Il36g interleukin 36, gamma JBrowse link 3 1,285,658 1,291,836 RGD:13792537
G Il36rn interleukin 36 receptor antagonist JBrowse link 3 1,385,256 1,392,275 RGD:13792537
G Inava innate immunity activator JBrowse link 13 53,088,438 53,108,713 RGD:1624291
RGD:1600115
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:1624291
RGD:13792537
G Irak4 interleukin-1 receptor-associated kinase 4 JBrowse link 7 135,803,723 135,831,006 RGD:1624291
RGD:13792537
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:5128809
G Jmjd8 jumonji domain containing 8 JBrowse link 10 15,195,954 15,198,870 RGD:1600115
RGD:1624291
G Litaf lipopolysaccharide-induced TNF factor JBrowse link 10 4,753,546 4,763,272 RGD:1600115
G LOC100910771 mitogen-activated protein kinase kinase kinase 7-like JBrowse link 9 114,022,058 114,077,887 RGD:13792537
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13673777
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:1624291
RGD:1600115
G Ltbr lymphotoxin beta receptor JBrowse link 4 157,822,838 157,829,291 RGD:1624291
RGD:13792537
G Ltf lactotransferrin JBrowse link 8 119,290,416 119,313,261 RGD:1624291
RGD:1600115
G Lurap1 leucine rich adaptor protein 1 JBrowse link 5 134,991,997 135,001,720 RGD:1624291
RGD:1600115
G Lurap1l leucine rich adaptor protein 1-like JBrowse link 5 98,468,039 98,515,126 RGD:1600115
G Map3k14 mitogen-activated protein kinase kinase kinase 14 JBrowse link 10 91,303,428 91,353,601 RGD:1624291
RGD:13792537
G Map3k3 mitogen activated protein kinase kinase kinase 3 JBrowse link 10 94,280,703 94,349,372 RGD:1624291
RGD:1600115
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:5508194
RGD:13792537
RGD:1624291
G Mid2 midline 2 JBrowse link X 112,019,897 112,121,980 RGD:1624291
RGD:1600115
G Mtdh metadherin JBrowse link 7 72,771,018 72,830,599 RGD:1624291
RGD:1600115
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1302746
RGD:1624291
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
RGD:1600115
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
RGD:13792537
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
RGD:1600115
G Peli1 pellino E3 ubiquitin protein ligase 1 JBrowse link 14 106,008,086 106,062,566 RGD:1624291
RGD:1600115
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase JBrowse link X 15,462,621 15,467,890 RGD:1624291
RGD:1600115
G Pink1 PTEN induced putative kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
RGD:1600115
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1600115
RGD:1624291
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Prkd1 protein kinase D1 JBrowse link 6 71,035,017 71,349,531 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1600115
RGD:1624291
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 JBrowse link 3 147,793,014 147,809,941 RGD:1624291
RGD:13792537
RGD:1600115
G Rel REL proto-oncogene, NF-kB subunit JBrowse link 14 108,490,794 108,517,582 RGD:1624291
RGD:1600115
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:1624291
RGD:1600115
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
RGD:1600115
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
RGD:1600115
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
RGD:1600115
G Rnf31 ring finger protein 31 JBrowse link 15 34,270,037 34,282,385 RGD:1624291
RGD:1600115
G Ror1 receptor tyrosine kinase-like orphan receptor 1 JBrowse link 5 118,892,874 119,239,528 RGD:1624291
RGD:13792537
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G S100a13 S100 calcium binding protein A13 JBrowse link 2 189,906,022 189,912,516 RGD:1624291
RGD:1600115
G S100a4 S100 calcium-binding protein A4 JBrowse link 2 189,997,278 189,999,587 RGD:1624291
RGD:1600115
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:1624291
RGD:1600115
G Sharpin SHANK-associated RH domain interactor JBrowse link 7 117,413,151 117,417,455 RGD:1624291
RGD:13792537
RGD:1600115
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 JBrowse link 1 1,999,574 2,017,574 RGD:1624291
RGD:1600115
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 JBrowse link X 54,035,958 54,090,282 RGD:1600115
RGD:1624291
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:1624291
RGD:1600115
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
RGD:1600115
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:1579987
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tifa TRAF-interacting protein with forkhead-associated domain JBrowse link 2 232,104,394 232,137,425 RGD:1600115
RGD:1624291
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
RGD:1600115
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
RGD:1600115
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1580306
RGD:13673777
RGD:1624291
G Tnfrsf19 TNF receptor superfamily member 19 JBrowse link 15 41,249,820 41,316,203 RGD:1624291
RGD:13792537
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:1600115
RGD:1624291
G Tnfsf10 TNF superfamily member 10 JBrowse link 2 113,008,008 113,026,899 RGD:1624291
RGD:1600115
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:1624291
G Tnip2 TNFAIP3 interacting protein 2 JBrowse link 14 81,487,934 81,505,889 RGD:1624291
RGD:1600115
G Tradd TNFRSF1A-associated via death domain JBrowse link 19 37,214,461 37,221,099 RGD:1624291
RGD:1600115
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:1624291
G Traf3ip2 Traf3 interacting protein 2 JBrowse link 20 44,679,861 44,722,874 RGD:1624291
RGD:13792537
G Traf5 TNF receptor-associated factor 5 JBrowse link 13 110,758,556 110,801,871 RGD:1624291
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
RGD:13792537
RGD:1600115
G Trim13 tripartite motif-containing 13 JBrowse link 15 41,897,191 41,936,545 RGD:1624291
RGD:1600115
G Trim25 tripartite motif-containing 25 JBrowse link 10 76,343,847 76,362,159 RGD:1624291
RGD:1600115
G Trim32 tripartite motif-containing 32 JBrowse link 5 81,431,554 81,449,023 RGD:1624291
RGD:1600115
G Trim38 tripartite motif containing 38 JBrowse link 17 43,600,006 43,607,879 RGD:1624291
G Trim5 tripartite motif-containing 5 JBrowse link 1 169,446,774 169,463,760 RGD:1624291
G Trim62 tripartite motif-containing 62 JBrowse link 5 147,068,725 147,099,024 RGD:1624291
RGD:1600115
G Trim8 tripartite motif-containing 8 JBrowse link 1 266,255,797 266,270,694 RGD:1624291
RGD:1600115
G Ubd ubiquitin D JBrowse link 20 1,876,175 1,878,126 RGD:1600115
RGD:13792537
RGD:1624291
G Ube2i ubiquitin-conjugating enzyme E2I JBrowse link 10 14,618,615 14,639,274 RGD:1624291
G Ube2n ubiquitin-conjugating enzyme E2N JBrowse link 7 36,610,147 36,640,190 RGD:1624291
G Ube2v1 ubiquitin conjugating enzyme E2 V1 JBrowse link 3 164,343,833 164,366,684 RGD:1624291
G Unc5cl unc-5 family C-terminal like JBrowse link 9 14,494,080 14,510,302 RGD:1624291
RGD:1600115
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 JBrowse link 4 66,012,111 66,062,160 RGD:1624291
positive regulation of I-kappaB phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
RGD:1600115
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:1600115
RGD:1624291
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:4892026
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:1624291
RGD:1600115
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17870
    positive regulation of biological process 6121
      positive regulation of signaling 1864
        positive regulation of signal transduction 1557
          positive regulation of intracellular signal transduction 971
            positive regulation of I-kappaB kinase/NF-kappaB signaling 132
              positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade 0
              positive regulation of I-kappaB phosphorylation 5
Path 2
Term Annotations click to browse term
  biological_process 17870
    biological regulation 12574
      regulation of biological process 11935
        regulation of cellular process 11277
          signal transduction 6525
            intracellular signal transduction 2532
              I-kappaB kinase/NF-kappaB signaling 205
                regulation of I-kappaB kinase/NF-kappaB signaling 183
                  positive regulation of I-kappaB kinase/NF-kappaB signaling 132
                    positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade 0
                    positive regulation of I-kappaB phosphorylation 5
paths to the root