Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:neurotrophin binding
go back to main search page
Accession:GO:0043121 term browser browse the term
Definition:Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
Comment:Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858].
Synonyms:exact_synonym: neurotrophic factor binding
 narrow_synonym: NT-3 binding;   NT-4 binding;   NT-4/5 binding;   NT-5 binding;   NT3 binding;   NT4 binding;   NT5 binding;   neurotrophin 3 binding;   neurotrophin 4/5 binding
 related_synonym: neurotrophin TRK receptor activity;   neurotrophin TRKA receptor activity;   neurotrophin TRKB receptor activity;   neurotrophin TRKC receptor activity
 alt_id: GO:0048404;   GO:0048405

show annotations for term's descendants           Sort by:
 
neurotrophin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) enables ISO MGI
RGD		 PMID:18596692 GO_REF:0000096 MGI:4417868 RGD:5508745 NCBI chr11:95,568,818...95,587,698
Ensembl chr11:95,568,818...95,587,735 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 enables IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:87,778,244...87,795,242
Ensembl chr 3:87,778,244...87,795,162 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 enables ISO
IDA
IBA		 (MGI:893826|PMID:1645620)
(MGI:6201960|PMID:21873635)		 MGI
UniProt
GO_Central		 PMID:1645620 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:6201960 MGI:893826 NCBI chr13:58,806,472...59,133,970
Ensembl chr13:58,806,569...59,133,970 		JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 enables IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:78,179,986...78,581,034
Ensembl chr 7:78,175,959...78,738,012 		JBrowse link
brain-derived neurotrophic factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin enables ISO MGI
RGD		 PMID:11813239 GO_REF:0000096 MGI:4417868 RGD:10046023 NCBI chr 6:121,636,165...121,679,238
Ensembl chr 6:121,635,376...121,679,227 		JBrowse link
G Fstl4 follistatin-like 4 enables IDA (MGI:5566541|PMID:24573299) MGI PMID:24573299 MGI:5566541 NCBI chr11:52,764,489...53,192,450
Ensembl chr11:52,764,634...53,188,538 		JBrowse link
G Hap1 huntingtin-associated protein 1 enables ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:100,347,327...100,356,982
Ensembl chr11:100,347,327...100,356,128 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 enables ISO
IBA
IDA		 (MGI:6201960|PMID:21873635)
(MGI:893826|PMID:1645620)		 MGI
RGD
GO_Central
UniProt		 PMID:1645620 PMID:16477614 PMID:16983663 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 MGI:893826 RGD:1626130 RGD:1626131 NCBI chr13:58,806,472...59,133,970
Ensembl chr13:58,806,569...59,133,970 		JBrowse link
G Pzp PZP, alpha-2-macroglobulin like enables ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:128,483,567...128,526,720
Ensembl chr 6:128,483,567...128,526,720 		JBrowse link
nerve growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin enables ISO MGI
RGD		 PMID:11813239 GO_REF:0000096 MGI:4417868 RGD:10046023 NCBI chr 6:121,636,165...121,679,238
Ensembl chr 6:121,635,376...121,679,227 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) enables ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:80,389,194...80,405,441
Ensembl chr 7:80,388,585...80,405,436 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) enables ISO
IBA
IDA		 (MGI:6201960|PMID:21873635)
(MGI:1098517|PMID:1317267)		 MGI
RGD
GO_Central		 PMID:1317267 PMID:3027580 PMID:21873635 GO_REF:0000096 MGI:1098517 MGI:4417868 MGI:6201960 RGD:728964 NCBI chr11:95,568,818...95,587,698
Ensembl chr11:95,568,818...95,587,735 		JBrowse link
G Nradd neurotrophin receptor associated death domain enables IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:110,621,135...110,624,393
Ensembl chr 9:110,621,135...110,624,452 		JBrowse link
G Ntf3 neurotrophin 3 enables ISO MGI
RGD		 PMID:2164684 GO_REF:0000096 MGI:4417868 RGD:729140 NCBI chr 6:126,101,412...126,166,772
Ensembl chr 6:126,101,412...126,166,910 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 NOT|enables ISO (PMID:15488758) UniProt
MGI
RGD		 PMID:9753156 PMID:15488758 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:5508802 NCBI chr 3:87,778,244...87,795,242
Ensembl chr 3:87,778,244...87,795,162 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 enables ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:65,862,136...66,050,386
Ensembl chr 7:65,861,734...66,050,386 		JBrowse link
G Pzp PZP, alpha-2-macroglobulin like enables ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:128,483,567...128,526,720
Ensembl chr 6:128,483,567...128,526,720 		JBrowse link
G Sort1 sortilin 1 enables ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:108,283,974...108,361,519
Ensembl chr 3:108,284,082...108,361,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 23082
    binding 16728
      protein binding 14451
        growth factor binding 153
          neurotrophin binding 13
            brain-derived neurotrophic factor binding 5
            nerve growth factor binding 9
paths to the root