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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of vascular permeability
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Accession:GO:0043114 term browser browse the term
Definition:Any process that modulates the extent to which blood vessels can be pervaded by fluid.

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regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase involved_in ISO (MGI:5475443|PMID:23152932) CACAO PMID:23152932 MGI:5475443 NCBI chrNW_004936538:6,674,595...6,819,511
Ensembl chrNW_004936538:6,674,907...6,816,674 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:288,377...432,297
Ensembl chrNW_004936619:288,340...432,315 		JBrowse link
G Cdh5 cadherin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:16,738,772...16,775,000
Ensembl chrNW_004936475:16,738,748...16,775,123 		JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:1,999,218...2,001,176
Ensembl chrNW_004936706:1,999,340...2,000,428 		JBrowse link
G Hrh1 histamine receptor H1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936602:2,182,053...2,185,297
Ensembl chrNW_004936602:2,183,831...2,185,297 		JBrowse link
G LOC101957084 plectin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:8,194,124...8,252,139
Ensembl chrNW_004936470:8,216,205...8,250,978 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18854840 RGD:2325137 NCBI chrNW_004936528:1,608,782...1,682,873
Ensembl chrNW_004936528:1,608,757...1,682,975 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
negative regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:8,005,223...8,007,586
Ensembl chrNW_004936528:8,005,189...8,007,643 		JBrowse link
G Adora2a adenosine A2a receptor ISO RGD PMID:16815983 RGD:1625437 NCBI chrNW_004936619:597,970...618,564
Ensembl chrNW_004936619:608,441...616,779 		JBrowse link
G Akap12 A-kinase anchoring protein 12 ISO RGD PMID:20454828 RGD:14348957 NCBI chrNW_004936489:4,237,466...4,258,408
Ensembl chrNW_004936489:4,237,439...4,261,141 		JBrowse link
G Amot angiomotin involved_in ISO (PMID:16043488) UniProt PMID:16043488 NCBI chrNW_004936499:2,594,190...2,661,307
Ensembl chrNW_004936499:2,594,239...2,661,359 		JBrowse link
G Angpt1 angiopoietin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1351100|PMID:10617467), (MGI:3722538|PMID:17562701) MGI
Ensembl		 PMID:10617467 PMID:17562701 GO_REF:0000107 MGI:1351100 MGI:3722538 NCBI chrNW_004936470:37,105,469...37,328,183
Ensembl chrNW_004936470:37,105,466...37,328,190 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3722538|PMID:17562701) MGI
Ensembl		 PMID:17562701 GO_REF:0000107 MGI:3722538 NCBI chrNW_004936664:714,036...788,584
Ensembl chrNW_004936664:713,984...789,344 		JBrowse link
G Cldn5 claudin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:3,455,508...3,457,053
Ensembl chrNW_004936619:3,456,166...3,456,822 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936608:262,653...397,753
Ensembl chrNW_004936608:262,445...397,762 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936697:1,927,817...2,008,268
Ensembl chrNW_004936697:1,927,812...2,008,268 		JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO (MGI:5317069|PMID:21081647) UniProt PMID:21081647 MGI:5317069 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:7648494 RGD:4892565 NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:1,856,256...1,944,405
Ensembl chrNW_004936498:1,856,144...1,944,412 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936548:5,758,634...6,072,195
Ensembl chrNW_004936548:5,762,507...6,070,576 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:1,161,764...1,234,800
Ensembl chrNW_004936562:1,165,304...1,211,817 		JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:17,479,899...17,481,788
Ensembl chrNW_004936490:17,479,650...17,482,716 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936477:8,111,212...8,448,567
Ensembl chrNW_004936477:8,109,228...8,446,653 		JBrowse link
G Tjp1 tight junction protein 1 ISO RGD PMID:20137299 RGD:2325126 NCBI chrNW_004936483:1,814,870...2,045,802
Ensembl chrNW_004936483:1,814,894...2,030,946 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:37,105,469...37,328,183
Ensembl chrNW_004936470:37,105,466...37,328,190 		JBrowse link
G Ocln occludin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:99,516...152,834
Ensembl chrNW_004936480:98,371...152,413 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chrNW_004936483:1,814,870...2,045,802
Ensembl chrNW_004936483:1,814,894...2,030,946 		JBrowse link
G Tjp2 tight junction protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:5,414,330...5,539,895
Ensembl chrNW_004936503:5,497,832...5,539,090 		JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
positive regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:4,707,658...4,871,865
Ensembl chrNW_004936534:4,709,064...4,871,023 		JBrowse link
G Capn1 calpain 1 ISO RGD PMID:21415394 RGD:13792556 NCBI chrNW_004936599:4,178,963...4,201,037
Ensembl chrNW_004936599:4,178,901...4,201,052 		JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 acts_upstream_of_or_within ISO (PMID:18669637) MGI PMID:18669637 NCBI chrNW_004936601:2,735,898...2,736,889 JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 involved_in ISO (PMID:17311300) AgBase PMID:17311300 NCBI chrNW_004936472:23,442,946...23,617,523
Ensembl chrNW_004936472:23,440,088...23,617,041 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:11739527 RGD:729357 NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:1,856,256...1,944,405
Ensembl chrNW_004936498:1,856,144...1,944,412 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936548:5,758,634...6,072,195
Ensembl chrNW_004936548:5,762,507...6,070,576 		JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5568017|PMID:24403062) MGI
Ensembl		 PMID:24403062 GO_REF:0000107 MGI:5568017 NCBI chrNW_004936470:10,042,903...10,052,475
Ensembl chrNW_004936470:10,042,906...10,052,480 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:18326823 RGD:2304321 NCBI chrNW_004936556:1,266,621...1,421,271
Ensembl chrNW_004936556:1,266,613...1,421,275 		JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:9374705 RGD:5147484 NCBI chrNW_004936521:9,053,179...9,065,790
Ensembl chrNW_004936521:9,053,179...9,065,797 		JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:21168935) UniProt PMID:21168935 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272 		JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:1,424,526...1,447,547
Ensembl chrNW_004936769:1,424,549...1,447,516 		JBrowse link
G Ucn urocortin ISO RGD PMID:19819946 RGD:5508179 NCBI chrNW_004936493:5,258,574...5,260,692
Ensembl chrNW_004936493:5,260,219...5,260,602 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:1351100|PMID:10617467), (MGI:5568017|PMID:24403062) RGD
Ensembl
MGI		 PMID:10617467 PMID:16793871 PMID:24403062 GO_REF:0000107 MGI:1351100 MGI:5568017 RGD:1580547 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673 		JBrowse link
G Vegfb vascular endothelial growth factor B NOT|involved_in ISO (PMID:16109918) UniProt PMID:16109918 NCBI chrNW_004936599:4,963,161...4,966,258
Ensembl chrNW_004936599:4,962,222...4,966,264 		JBrowse link
regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 ISO RGD PMID:34334113 RGD:155882538 NCBI chrNW_004936469:32,240,730...32,372,413
Ensembl chrNW_004936469:32,240,835...32,371,267 		JBrowse link
regulation of vascular permeability involved in acute inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd4a C2 calcium dependent domain containing 4A involved_in ISO (PMID:15527968) UniProt PMID:15527968 NCBI chrNW_004936471:22,847,090...22,850,006 JBrowse link
G C2cd4b C2 calcium dependent domain containing 4B involved_in ISO (PMID:15527968) UniProt PMID:15527968 NCBI chrNW_004936471:22,939,454...22,941,728 JBrowse link
G LOC101965661 beta-catenin-interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:3,696,686...3,729,017
Ensembl chrNW_004936623:3,782,005...3,806,619
Ensembl chrNW_004936623:3,782,005...3,806,619 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:89,717...137,866
Ensembl chrNW_004936475:89,570...126,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15031
    biological regulation 10541
      regulation of biological quality 2703
        regulation of vascular permeability 45
          negative regulation of vascular permeability + 20
          positive regulation of vascular permeability + 20
          regulation of blood-brain barrier permeability + 7
          regulation of lymphatic vascular permeability 0
          regulation of transport across blood-brain barrier + 1
          regulation of vascular permeability involved in acute inflammatory response 4
Path 2
Term Annotations click to browse term
  biological_process 15031
    multicellular organismal process 7329
      system process 2402
        circulatory system process 528
          vascular process in circulatory system 224
            regulation of vascular permeability 45
              negative regulation of vascular permeability + 20
              positive regulation of vascular permeability + 20
              regulation of blood-brain barrier permeability + 7
              regulation of lymphatic vascular permeability 0
              regulation of transport across blood-brain barrier + 1
              regulation of vascular permeability involved in acute inflammatory response 4
paths to the root