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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of vascular permeability
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Accession:GO:0043114 term browser browse the term
Definition:Any process that modulates the extent to which blood vessels can be pervaded by fluid.


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regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr active BCR-related gene involved_in IMP (MGI:5475443|PMID:23152932) CACAO PMID:23152932 MGI:5475443 NCBI chr11:76,307,558...76,468,565
Ensembl chr11:76,307,560...76,514,384 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase involved_in IMP (MGI:5475443|PMID:23152932) CACAO PMID:23152932 MGI:5475443 NCBI chr10:74,896,384...75,020,755
Ensembl chr10:74,896,424...75,020,753 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:104,828,247...104,871,136
Ensembl chr 8:104,828,257...104,871,143 		JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in IMP (MGI:6414996|PMID:32058960) UniProt PMID:32058960 MGI:6414996 NCBI chr 7:18,946,463...18,958,101
Ensembl chr 7:18,946,463...18,958,099 		JBrowse link
G Hrh1 histamine receptor H1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 6:114,374,897...114,460,259
Ensembl chr 6:114,374,897...114,460,257 		JBrowse link
G Plec plectin involved_in IMP (MGI:5790023|PMID:26519478) MGI PMID:26519478 MGI:5790023 NCBI chr15:76,055,174...76,115,578
Ensembl chr15:76,055,174...76,116,774 		JBrowse link
G Plvap plasmalemma vesicle associated protein involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:71,950,397...71,964,446
Ensembl chr 8:71,950,409...71,964,396 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 involved_in ISO RGD
MGI		 PMID:18854840 GO_REF:0000096 MGI:4417868 RGD:2325137 NCBI chr 7:45,753,947...45,829,457
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Sh3gl2 SH3-domain GRB2-like 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:85,123,340...85,307,617
Ensembl chr 4:85,123,363...85,557,432 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
negative regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in IMP (MGI:3772552|PMID:18097473) UniProt PMID:18097473 MGI:3772552 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Adora2a adenosine A2a receptor involved_in ISO RGD
MGI		 PMID:16815983 GO_REF:0000096 MGI:4417868 RGD:1625437 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618 		JBrowse link
G Akap12 A kinase (PRKA) anchor protein (gravin) 12 involved_in ISO RGD
MGI		 PMID:20454828 GO_REF:0000096 MGI:4417868 RGD:14348957 NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470 		JBrowse link
G Amot angiomotin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:144,229,420...144,288,962
Ensembl chr  X:144,229,421...144,288,177 		JBrowse link
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 ISO
IDA		 (MGI:1351100|PMID:10617467), (MGI:3722538|PMID:17562701) MGI PMID:10617467 PMID:17562701 GO_REF:0000096 MGI:1351100 MGI:3722538 MGI:4834177 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 acts_upstream_of_or_within IMP (MGI:3722538|PMID:17562701) MGI PMID:17562701 MGI:3722538 NCBI chr 7:16,228,398...16,349,313
Ensembl chr 7:16,227,644...16,348,918 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP (MGI:5317069|PMID:21081647) UniProt PMID:21081647 MGI:5317069 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028 		JBrowse link
G Cldn5 claudin 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:145,464,447...145,600,032
Ensembl chr 3:145,464,430...145,600,032 		JBrowse link
G Fermt2 fermitin family member 2 involved_in IMP
ISO		 (MGI:6467695|PMID:28799653) ARUK-UCL
MGI		 PMID:28799653 GO_REF:0000096 MGI:4834177 MGI:6467695 NCBI chr14:45,696,249...45,767,767
Ensembl chr14:45,696,252...45,767,575 		JBrowse link
G Mir23a microRNA 23a involved_in ISO (PMID:27741223) BHF-UCL PMID:27741223 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in ISO RGD
MGI		 PMID:7648494 GO_REF:0000096 MGI:4417868 RGD:4892565 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:101,070,898...101,162,036
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026 		JBrowse link
G Pde3a phosphodiesterase 3A, cGMP inhibited involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:141,194,995...141,452,588
Ensembl chr 6:141,194,995...141,453,174 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:90,260,100...90,411,102
Ensembl chr 2:90,260,098...90,410,939 		JBrowse link
G Ramp2 receptor (calcitonin) activity modifying protein 2 involved_in IMP
ISO		 (MGI:3772552|PMID:18097473) UniProt
MGI		 PMID:18097473 GO_REF:0000096 MGI:3772552 MGI:4834177 NCBI chr11:101,137,160...101,139,076
Ensembl chr11:101,136,854...101,150,372 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:48,138,633...48,465,077
Ensembl chr 5:48,140,480...48,465,075 		JBrowse link
G Tjp1 tight junction protein 1 ISO RGD PMID:20137299 RGD:2325126 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Ocln occludin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tjp2 tight junction protein 2 involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI		 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394 		JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:81,109,022...81,127,415
Ensembl chr10:81,109,041...81,127,415 		JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
positive regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:38,529,692...38,684,290
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Capn1 calpain 1 involved_in ISO RGD
MGI		 PMID:21415394 GO_REF:0000096 MGI:4417868 RGD:13792556 NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927 		JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 involved_in ISO RGD
MGI		 PMID:10679105 GO_REF:0000096 MGI:4417868 RGD:68880 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 involved_in ISO RGD
MGI		 PMID:19255141 GO_REF:0000096 MGI:4417868 RGD:7257695 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,148...74,200,405 		JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr19:36,894,950...36,896,999
Ensembl chr19:36,894,950...36,897,015 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 involved_in ISO (PMID:17311300) AgBase PMID:17311300 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Il18 interleukin 18 involved_in ISO RGD
MGI		 PMID:11739527 GO_REF:0000096 MGI:4417868 RGD:729357 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:101,070,898...101,162,036
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026 		JBrowse link
G Pde3a phosphodiesterase 3A, cGMP inhibited involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:141,194,995...141,452,588
Ensembl chr 6:141,194,995...141,453,174 		JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4a3 acts_upstream_of_or_within IMP (MGI:5568017|PMID:24403062) MGI PMID:24403062 MGI:5568017 NCBI chr15:73,594,994...73,630,615
Ensembl chr15:73,594,994...73,630,615 		JBrowse link
G Tacr1 tachykinin receptor 1 involved_in ISO RGD
MGI		 PMID:18326823 GO_REF:0000096 MGI:4417868 RGD:2304321 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085 		JBrowse link
G Tacr2 tachykinin receptor 2 involved_in ISO RGD
MGI		 PMID:9374705 GO_REF:0000096 MGI:4417868 RGD:5147484 NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in IMP
ISO		 (MGI:5688830|PMID:23136043) UniProt
MGI		 PMID:23136043 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:5688830 NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482 		JBrowse link
G Ucn urocortin involved_in ISO RGD
MGI		 PMID:19819946 GO_REF:0000096 MGI:4417868 RGD:5508179 NCBI chr 5:31,295,333...31,296,239
Ensembl chr 5:31,295,407...31,296,173 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within
involved_in		 IDA
ISO		 (MGI:1351100|PMID:10617467), (MGI:5568017|PMID:24403062) MGI
RGD		 PMID:10617467 PMID:16793871 PMID:24403062 GO_REF:0000096 MGI:1351100 MGI:4417868 MGI:4834177 MGI:5568017 RGD:1580547 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vegfb vascular endothelial growth factor B NOT|involved_in ISO (PMID:16109918) UniProt PMID:16109918 NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019 		JBrowse link
regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 ISO RGD PMID:34334113 RGD:155882538 NCBI chr 2:44,873,524...45,007,454
Ensembl chr 2:44,873,644...45,007,407 		JBrowse link
regulation of vascular permeability involved in acute inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd4a C2 calcium-dependent domain containing 4A involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:67,737,814...67,739,612
Ensembl chr 9:67,737,771...67,739,612 		JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:67,623,506...67,668,215
Ensembl chr 9:67,666,719...67,668,212 		JBrowse link
G Ctnnbip1 catenin beta interacting protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:149,602,698...149,650,894
Ensembl chr 4:149,602,693...149,650,894 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28454
    biological regulation 13206
      regulation of biological quality 3280
        regulation of vascular permeability 51
          negative regulation of vascular permeability + 22
          positive regulation of vascular permeability + 23
          regulation of blood-brain barrier permeability + 9
          regulation of lymphatic vascular permeability 0
          regulation of transport across blood-brain barrier + 1
          regulation of vascular permeability involved in acute inflammatory response 4
Path 2
Term Annotations click to browse term
  biological_process 28454
    multicellular organismal process 9292
      system process 3282
        circulatory system process 604
          vascular process in circulatory system 257
            regulation of vascular permeability 51
              negative regulation of vascular permeability + 22
              positive regulation of vascular permeability + 23
              regulation of blood-brain barrier permeability + 9
              regulation of lymphatic vascular permeability 0
              regulation of transport across blood-brain barrier + 1
              regulation of vascular permeability involved in acute inflammatory response 4
paths to the root