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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of vascular permeability
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Accession:GO:0043114 term browser browse the term
Definition:Any process that modulates the extent to which blood vessels can be pervaded by fluid.



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regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABR ABR activator of RhoGEF and GTPase involved_in ISO (MGI:5475443|PMID:23152932) CACAO PMID:23152932 MGI:5475443 NCBI chr17:1,003,519...1,229,722
Ensembl chr17:1,003,519...1,229,738
JBrowse link
G AZU1 azurocidin 1 involved_in NAS (PMID:11861296) UniProt
UniProt
PMID:11861296 NCBI chr19:827,837...832,018
Ensembl chr19:825,097...832,018
JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037
JBrowse link
G BDKRB2 bradykinin receptor B2 involved_in IC (PMID:17077303) BHF-UCL
BHF-UCL
PMID:17077303 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G CDH5 cadherin 5 involved_in IDA (PMID:26598555) ARUK-UCL
ARUK-UCL
PMID:26598555 NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,622...66,404,784
JBrowse link
G GPR4 G protein-coupled receptor 4 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr19:45,589,764...45,602,212
Ensembl chr19:45,589,764...45,602,212
JBrowse link
G HRH1 histamine receptor H1 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
JBrowse link
G NPPB natriuretic peptide B involved_in TAS (PMID:14737067) UniProt
UniProt
PMID:14737067 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NPR1 natriuretic peptide receptor 1 involved_in TAS (PMID:14737067) UniProt
UniProt
PMID:14737067 NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992
JBrowse link
G PLEC plectin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:143,915,153...143,976,745
Ensembl chr 8:143,915,153...143,976,734
JBrowse link
G PLVAP plasmalemma vesicle associated protein involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,342
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS (PMID:19267251) BHF-UCL
BHF-UCL
PMID:19267251 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G TEK TEK receptor tyrosine kinase involved_in TAS (PMID:18366015), (PMID:18425120) UniProt
UniProt
PMID:18366015 PMID:18425120 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174
JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase involved_in TAS (PMID:19267251) BHF-UCL
BHF-UCL
PMID:19267251 NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546
JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:18854840 GO_REF:0000107 RGD:2325137 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894
JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in IMP (PMID:24854121) ARUK-UCL
ARUK-UCL
PMID:24854121 NCBI chr 9:17,579,066...17,797,124
Ensembl chr 9:17,579,066...17,797,124
JBrowse link
G VEGFA vascular endothelial growth factor A involved_in IMP (PMID:19148554) ARUK-UCL
ARUK-UCL
PMID:19148554 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IDA (PMID:24345162) Alzheimers_University_of_Toronto
Alzheimers_University_of_Toronto
PMID:24345162 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
negative regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G ADORA2A adenosine A2a receptor involved_in IEA
ISO
Ensembl
RGD
Ensembl
PMID:16815983 GO_REF:0000107 RGD:1625437 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G AKAP12 A-kinase anchoring protein 12 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:20454828 GO_REF:0000107 RGD:14348957 NCBI chr 6:151,239,967...151,358,559
Ensembl chr 6:151,239,967...151,358,559
JBrowse link
G AMOT angiomotin involved_in IDA (PMID:16043488) UniProt
UniProt
PMID:16043488 NCBI chr  X:112,774,877...112,840,831
Ensembl chr  X:112,774,503...112,840,831
JBrowse link
G ANGPT1 angiopoietin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
IDA
(MGI:1351100|PMID:10617467), (MGI:3722538|PMID:17562701)
(PMID:14978158), (PMID:19297368)
MGI
Ensembl
UniProt
UniProt
PMID:10617467 PMID:14978158 PMID:17562701 PMID:19297368 GO_REF:0000107 MGI:1351100 MGI:3722538 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3722538|PMID:17562701) Ensembl
Ensembl
MGI
PMID:17562701 GO_REF:0000107 MGI:3722538 NCBI chr19:46,860,997...47,005,077
Ensembl chr19:46,860,997...47,005,077
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234
JBrowse link
G CLDN5 claudin 5 involved_in IMP (PMID:28961379) ARUK-UCL
ARUK-UCL
PMID:28961379 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 involved_in IDA (PMID:24895913) BHF-UCL
BHF-UCL
PMID:24895913 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363
JBrowse link
G FERMT2 FERM domain containing kindlin 2 involved_in IMP
IEA
(PMID:28799653) ARUK-UCL
ARUK-UCL
Ensembl
PMID:28799653 GO_REF:0000107 NCBI chr14:52,857,273...52,951,050
Ensembl chr14:52,857,268...52,952,435
JBrowse link
G MIR23A microRNA 23a involved_in IDA (PMID:27741223) BHF-UCL PMID:27741223 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:7648494 RGD:4892565 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G PDE2A phosphodiesterase 2A involved_in IMP (PMID:17704206) UniProt
UniProt
PMID:17704206 NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591
JBrowse link
G PDE3A phosphodiesterase 3A involved_in IMP (PMID:17704206) UniProt
UniProt
PMID:17704206 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IDA (PMID:19332538) UniProt
UniProt
PMID:19332538 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839
JBrowse link
G RAMP2 receptor activity modifying protein 2 involved_in IDA
IEA
(PMID:18097473) UniProt
UniProt
Ensembl
PMID:18097473 GO_REF:0000107 NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IDA (PMID:18345009) UniProt
UniProt
PMID:18345009 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561
JBrowse link
G TJP1 tight junction protein 1 involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:20137299 GO_REF:0000107 RGD:2325126 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 involved_in IMP (PMID:19148554) ARUK-UCL
ARUK-UCL
PMID:19148554 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G OCLN occludin involved_in IMP (PMID:24854121) ARUK-UCL
ARUK-UCL
PMID:24854121 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G TJP1 tight junction protein 1 involved_in IMP
IBA
(PMID:24854121)
(PMID:21873635)
ARUK-UCL
GO_Central
ARUK-UCL
GO_Central
PMID:21873635 PMID:24854121 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
G TJP2 tight junction protein 2 involved_in IMP
IBA
(PMID:19148554)
(PMID:21873635)
ARUK-UCL
GO_Central
ARUK-UCL
GO_Central
PMID:19148554 PMID:21873635 NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615
JBrowse link
G TJP3 tight junction protein 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr19:3,708,384...3,750,813
Ensembl chr19:3,708,362...3,750,813
JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IDA (PMID:24345162) Alzheimers_University_of_Toronto
Alzheimers_University_of_Toronto
PMID:24345162 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
positive regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IDA (PMID:26598555) ARUK-UCL
ARUK-UCL
PMID:26598555 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G CAPN1 calpain 1 ISO RGD PMID:21415394 RGD:13792556 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CCL4 C-C motif chemokine ligand 4 ISO RGD PMID:10679105 RGD:68880 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 involved_in ISO
IEA
RGD
Ensembl
PMID:19255141 GO_REF:0000107 RGD:7257695 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G FGFBP3 fibroblast growth factor binding protein 3 acts_upstream_of_or_within IDA (PMID:18669637) MGI
MGI
PMID:18669637 NCBI chr10:91,906,584...91,909,486
Ensembl chr10:91,906,584...91,909,486
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 involved_in ISO (PMID:17311300) AgBase PMID:17311300 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:11739527 RGD:729357 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G PDE2A phosphodiesterase 2A involved_in IMP (PMID:17704206) UniProt
UniProt
PMID:17704206 NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591
JBrowse link
G PDE3A phosphodiesterase 3A involved_in IMP (PMID:17704206) UniProt
UniProt
PMID:17704206 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583
JBrowse link
G PTP4A3 protein tyrosine phosphatase 4A3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5568017|PMID:24403062) Ensembl
Ensembl
MGI
PMID:24403062 GO_REF:0000107 MGI:5568017 NCBI chr 8:141,392,021...141,432,454
Ensembl chr 8:141,391,995...141,432,454
JBrowse link
G TACR1 tachykinin receptor 1 involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:18326823 GO_REF:0000107 RGD:2304321 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G TACR2 tachykinin receptor 2 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:9374705 GO_REF:0000107 RGD:5147484 NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IDA (PMID:21168935) UniProt
UniProt
PMID:21168935 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in IMP
IEA
(PMID:23136043) UniProt
UniProt
Ensembl
PMID:23136043 GO_REF:0000107 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
JBrowse link
G UCN urocortin involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:19819946 GO_REF:0000107 RGD:5508179 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445
JBrowse link
G VEGFA vascular endothelial growth factor A acts_upstream_of_or_within
involved_in
ISO
IDA
(MGI:1351100|PMID:10617467), (MGI:5568017|PMID:24403062)
(PMID:16109918), (PMID:26598555)
MGI
ARUK-UCL
RGD
ARUK-UCL
PMID:10617467 PMID:16109918 PMID:16793871 PMID:24403062 PMID:26598555 MGI:1351100 MGI:5568017 RGD:1580547 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VEGFB vascular endothelial growth factor B NOT|involved_in IDA (PMID:16109918) UniProt
UniProt
PMID:16109918 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264
JBrowse link
regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZEB2 zinc finger E-box binding homeobox 2 ISO RGD PMID:34334113 RGD:155882538 NCBI chr 2:144,384,081...144,520,119
Ensembl chr 2:144,364,364...144,521,057
JBrowse link
regulation of vascular permeability involved in acute inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2CD4A C2 calcium dependent domain containing 4A involved_in IDA (PMID:15527968) UniProt
UniProt
PMID:15527968 NCBI chr15:62,066,977...62,070,917
Ensembl chr15:62,066,977...62,070,917
JBrowse link
G C2CD4B C2 calcium dependent domain containing 4B involved_in IDA (PMID:15527968) UniProt
UniProt
PMID:15527968 NCBI chr15:62,163,535...62,165,285
Ensembl chr15:62,163,535...62,165,285
JBrowse link
G CTNNBIP1 catenin beta interacting protein 1 involved_in IMP (PMID:18287330) BHF-UCL
BHF-UCL
PMID:18287330 NCBI chr 1:9,848,276...9,910,269
Ensembl chr 1:9,848,276...9,910,336
JBrowse link
G MYLK3 myosin light chain kinase 3 involved_in IMP (PMID:18390750) BHF-UCL
BHF-UCL
PMID:18390750 NCBI chr16:46,702,282...46,763,246
Ensembl chr16:46,702,282...46,790,407
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19771
    biological regulation 13757
      regulation of biological quality 3439
        regulation of vascular permeability 58
          negative regulation of vascular permeability + 22
          positive regulation of vascular permeability + 23
          regulation of blood-brain barrier permeability + 9
          regulation of lymphatic vascular permeability 0
          regulation of transport across blood-brain barrier + 1
          regulation of vascular permeability involved in acute inflammatory response 4
Path 2
Term Annotations click to browse term
  biological_process 19771
    multicellular organismal process 8918
      system process 2750
        circulatory system process 731
          vascular process in circulatory system 331
            regulation of vascular permeability 58
              negative regulation of vascular permeability + 22
              positive regulation of vascular permeability + 23
              regulation of blood-brain barrier permeability + 9
              regulation of lymphatic vascular permeability 0
              regulation of transport across blood-brain barrier + 1
              regulation of vascular permeability involved in acute inflammatory response 4
paths to the root