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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of vascular permeability
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Accession:GO:0043114 term browser browse the term
Definition:Any process that modulates the extent to which blood vessels can be pervaded by fluid.


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regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase involved_in ISO (PMID:23152932) RGD PMID:23152932 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase involved_in ISO (PMID:23152932) RGD PMID:23152932 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:26598555) RGD PMID:26598555 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32058960)		 UniProt
RGD		 PMID:32058960 GO_REF:0000024 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Hrh1 histamine receptor H 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Plec plectin involved_in IEA
ISO		 GO_REF:0000107
MGI:3721885 (PMID:26519478)		 Ensembl
RGD		 PMID:26519478 GO_REF:0000107 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Plvap plasmalemma vesicle associated protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:18854840 RGD:2325137 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Ifnb1 interferon beta 1 IDA RGD PMID:12973019 PMID:12973022 RGD:401851924, RGD:401851925 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISO
IEA		 (PMID:24854121)
GO_REF:0000107		 RGD
Ensembl		 PMID:24854121 GO_REF:0000107 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA		 (PMID:19148554)
GO_REF:0000107		 RGD
Ensembl		 PMID:19148554 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24345162) RGD PMID:24345162 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
negative regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:18097473) RGD PMID:18097473 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adora2a adenosine A2a receptor IMP RGD PMID:16815983 RGD:1625437 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Akap12 A-kinase anchoring protein 12 IMP RGD PMID:20454828 RGD:14348957 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Amot angiomotin involved_in ISO (PMID:16043488) RGD PMID:16043488 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10617467), (PMID:17562701)
(PMID:14978158), (PMID:19297368)		 Ensembl
RGD		 PMID:10617467 PMID:14978158 PMID:17562701 PMID:19297368 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 acts_upstream_of_or_within ISO (PMID:17562701) RGD PMID:17562701 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Cdc45 cell division cycle 45 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21081647)		 UniProt
RGD		 PMID:21081647 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:28961379) RGD PMID:28961379 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 involved_in ISO (PMID:24895913) RGD PMID:24895913 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:28799653) RGD PMID:28799653 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Mir23a microRNA 23a involved_in ISO (PMID:27741223) RGD PMID:27741223 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:7648494 RGD:4892565 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO
ISS
IEA		 (PMID:17704206)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17704206 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISO (PMID:17704206) RGD PMID:17704206 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:19332538) RGD PMID:19332538 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISO
ISS		 (PMID:18097473)
GO_REF:0000024		 RGD
UniProt		 PMID:18097473 GO_REF:0000024 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:18345009)
GO_REF:0000107		 RGD
Ensembl		 PMID:18345009 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Tjp1 tight junction protein 1 IEP RGD PMID:20137299 RGD:2325126 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19148554)		 Ensembl
RGD		 PMID:19148554 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Ocln occludin involved_in ISO (PMID:24854121) RGD PMID:24854121 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO
IBA		 (PMID:24854121)
GO_REF:0000033		 RGD
GO_Central		 PMID:24854121 GO_REF:0000033 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 involved_in ISO
IBA		 (PMID:19148554)
GO_REF:0000033		 RGD
GO_Central		 PMID:19148554 GO_REF:0000033 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279 		JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:24345162)		 Ensembl
RGD		 PMID:24345162 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
positive regulation of vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:26598555) RGD PMID:26598555 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Capn1 calpain 1 IMP RGD PMID:21415394 RGD:13792556 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IDA RGD PMID:10679105 RGD:68880 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:19255141 RGD:7257695 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 acts_upstream_of_or_within ISO (PMID:18669637) RGD PMID:18669637 NCBI chr 1:234,644,023...234,646,028
Ensembl chr 1:234,644,019...234,646,547 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 involved_in ISO (PMID:17311300) RGD PMID:17311300 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:11739527 RGD:729357 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO
IEA
ISS		 (PMID:17704206)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17704206 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISO (PMID:17704206) RGD PMID:17704206 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 acts_upstream_of_or_within ISO MGI:5461469 (PMID:24403062) RGD PMID:24403062 NCBI chr 7:105,650,640...105,660,921
Ensembl chr 7:105,628,029...105,660,919 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:18326823 RGD:2304321 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tacr2 tachykinin receptor 2 IMP RGD PMID:9374705 RGD:5147484 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:21168935) RGD PMID:21168935 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in IMP
ISO		 PMID:23136043
(PMID:23136043)		 RGD PMID:23136043 PMID:23136043 RGD:10400856 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Ucn urocortin IDA RGD PMID:19819946 RGD:5508179 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 (PMID:10617467), (PMID:24403062)
GO_REF:0000107
(PMID:16109918)
(PMID:26598555)		 RGD
Ensembl		 PMID:10617467 PMID:16109918 PMID:24403062 PMID:26598555 PMID:16793871 GO_REF:0000107, RGD:1580547 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B NOT|involved_in ISO (PMID:16109918) RGD PMID:16109918 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 IMP RGD PMID:34334113 RGD:155882538 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
regulation of vascular permeability involved in acute inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd4a C2 calcium-dependent domain containing 4A involved_in ISO (PMID:15527968) RGD PMID:15527968 NCBI chr 8:68,467,017...68,469,781
Ensembl chr 8:68,466,664...68,470,031 		JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B involved_in ISO (PMID:15527968) RGD PMID:15527968 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 involved_in ISO (PMID:18287330) RGD PMID:18287330 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological quality 3418
        regulation of vascular permeability 52
          negative regulation of vascular permeability + 24
          positive regulation of vascular permeability + 23
          regulation of blood-brain barrier permeability + 10
          regulation of lymphatic vascular permeability 0
          regulation of transport across blood-brain barrier + 1
          regulation of vascular permeability involved in acute inflammatory response 3
Path 2
Term Annotations click to browse term
  biological_process 20076
    multicellular organismal process 8906
      system process 3539
        circulatory system process 620
          vascular process in circulatory system 273
            regulation of vascular permeability 52
              negative regulation of vascular permeability + 24
              positive regulation of vascular permeability + 23
              regulation of blood-brain barrier permeability + 10
              regulation of lymphatic vascular permeability 0
              regulation of transport across blood-brain barrier + 1
              regulation of vascular permeability involved in acute inflammatory response 3
paths to the root