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ONTOLOGY REPORT - ANNOTATIONS

Term:peptide biosynthetic process
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Accession:GO:0043043 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.
Synonyms:exact_synonym: peptide anabolism;   peptide biosynthesis;   peptide formation;   peptide synthesis

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peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMD dystrophin involved_in ISO (PMID:16000376) UniProt PMID:16000376 NCBI chr  X:29,543,003...32,218,011 JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in ISO (PMID:8262946) BHF-UCL PMID:8262946 NCBI chr29:8,980,367...8,992,257
Ensembl chr29:8,979,720...8,988,235 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 involved_in ISO (MGI:3773775|PMID:8262946) BHF-UCL PMID:8262946 MGI:3773775 NCBI chr 4:90,246,413...90,289,148
Ensembl chr 4:90,248,598...90,289,089 		JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in ISO (MGI:3795695|PMID:18519639), (MGI:74959|PMID:8468318)
(PMID:18519639), (PMID:8468318)
(PMID:8901832)		 BHF-UCL PMID:8468318 PMID:8901832 PMID:18519639 MGI:3795695 MGI:74959 NCBI chr12:86,907,173...87,367,935
Ensembl chr12:87,042,557...87,367,033 		JBrowse link
amino acid activation for nonribosomal peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDH aminoadipate-semialdehyde dehydrogenase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24467666) Ensembl
TreeGrafter
MGI		 PMID:24467666 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:12,248,193...12,292,027
Ensembl chr 7:12,249,208...12,296,516 		JBrowse link
antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LGALS4 galectin 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:33,428,839...33,436,904 JBrowse link
G LOC103235499 galectin-4 acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chr 6:33,428,746...33,437,453 JBrowse link
G MMP7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) MGI PMID:20056603 NCBI chr 1:93,889,189...93,901,077
Ensembl chr 1:93,889,198...93,899,587 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-negative bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELANE elastase, neutrophil expressed involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:599,392...604,925
Ensembl chr 6:601,217...604,725 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15692051) MGI PMID:15692051 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
bradykinin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO (PMID:12485443) MGI PMID:12485443 NCBI chr26:37,605,891...37,622,302
Ensembl chr26:37,604,412...37,622,083 		JBrowse link
glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLC glutamate-cysteine ligase catalytic subunit involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:10805773)
(PMID:16081425)		 RGD
TreeGrafter
MGI
UniProt
InterPro		 PMID:10805773 PMID:16081425 PMID:16183645 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000117 GO_REF:0000118 RGD:1582661 NCBI chr17:19,012,994...19,060,617
Ensembl chr17:19,013,026...19,060,659 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16081425) RGD
TreeGrafter
MGI
UniProt
InterPro		 PMID:16081425 PMID:16183645 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000118 RGD:1582661 NCBI chr20:39,339,948...39,359,980
Ensembl chr20:39,339,908...39,359,430 		JBrowse link
G GSS glutathione synthetase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:81780|PMID:8660701) RGD
GOC
UniProt
InterPro		 PMID:8660701 PMID:10964706 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 MGI:81780 RGD:1599340 NCBI chr 2:39,230,629...39,258,511
Ensembl chr 2:39,230,487...39,254,648 		JBrowse link
G HAGH hydroxyacylglutathione hydrolase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:1,705,436...1,730,896
Ensembl chr 5:1,713,542...1,730,797 		JBrowse link
G LOC103223058 glutathione hydrolase light chain 2 involved_in ISO (MGI:5294309|PMID:12468440) UniProt PMID:12468440 MGI:5294309 NCBI chr19:7,353,922...7,406,392 JBrowse link
G MGST2 microsomal glutathione S-transferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:86,629,691...86,666,912
Ensembl chr 7:86,629,642...86,666,857 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in ISO (PMID:12614333) MGI PMID:12614333 NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369 		JBrowse link
G SLC1A2 solute carrier family 1 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:29,845,512...30,012,261
Ensembl chr 1:29,847,043...29,989,975 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
positive regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:5616326|PMID:14978030)
(PMID:14978030)		 ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr14:18,135,973...18,209,471
Ensembl chr14:18,136,291...18,209,457 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:5616326|PMID:14978030)
(PMID:14978030)		 ParkinsonsUK-UCL PMID:14978030 MGI:5616326 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
regulation of glutathione biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A11 solute carrier family 7 member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16037214) Ensembl
MGI		 PMID:16037214 GO_REF:0000107 NCBI chr 7:85,149,810...85,225,061
Ensembl chr 7:85,154,068...85,225,144 		JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDH2 3-hydroxybutyrate dehydrogenase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:51,185,303...51,206,300
Ensembl chr 7:51,183,107...51,206,261 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17106
    cellular process 16633
      metabolic process 11190
        biosynthetic process 7649
          peptide biosynthetic process 23
            antimicrobial peptide biosynthetic process + 5
            bradykinin biosynthetic process 1
            nonribosomal peptide biosynthetic process + 13
            peptide antibiotic biosynthetic process + 0
paths to the root