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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA aminoacylation
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Accession:GO:0043039 term browser browse the term
Definition:The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
Synonyms:exact_synonym: aminoacyl-tRNA biosynthesis;   aminoacyl-tRNA biosynthetic process;   tRNA charging

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tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dars2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624771:8,003,208...8,033,981
Ensembl chrNW_004624771:8,003,295...8,034,043 		JBrowse link
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624756:19,550,198...20,016,561
Ensembl chrNW_004624756:19,550,103...19,928,538 		JBrowse link
G Yars2 tyrosyl-tRNA synthetase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624778:3,382,993...3,390,357
Ensembl chrNW_004624778:3,383,017...3,390,036 		JBrowse link
alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16906134) TreeGrafter
Ensembl
InterPro
MGI
RGD		 PMID:2040280 PMID:16906134 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2302982 NCBI chrNW_004624746:12,540,969...12,566,989
Ensembl chrNW_004624746:12,540,633...12,567,376 		JBrowse link
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624754:15,563,878...15,573,538
Ensembl chrNW_004624754:15,563,872...15,573,536 		JBrowse link
G LOC101708260 alanyl-tRNA editing protein Aarsd1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624795:1,281,617...1,300,798
Ensembl chrNW_004624795:1,291,678...1,301,671 		JBrowse link
arginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dalrd3 DALR anticodon binding domain containing 3 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624730:3,063,241...3,066,253
Ensembl chrNW_004624730:3,063,245...3,066,453 		JBrowse link
G Rars1 arginyl-tRNA synthetase 1 involved_in ISO
IEA		 RGD
InterPro
TreeGrafter		 PMID:7082655 GO_REF:0000002 GO_REF:0000118 RGD:2303394 NCBI chrNW_004624733:21,487,847...21,535,487
Ensembl chrNW_004624733:21,487,847...21,535,797 		JBrowse link
G Rars2 arginyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624799:6,728,967...6,804,846
Ensembl chrNW_004624799:6,728,610...6,803,716 		JBrowse link
asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nars1 asparaginyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624792:3,109,779...3,128,949
Ensembl chrNW_004624792:3,109,779...3,128,957 		JBrowse link
aspartyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dars1 aspartyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624732:35,266,830...35,337,610
Ensembl chrNW_004624732:35,266,830...35,337,645 		JBrowse link
G Dars2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624771:8,003,208...8,033,981
Ensembl chrNW_004624771:8,003,295...8,034,043 		JBrowse link
cysteinyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cars1 cysteinyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624767:15,749,862...15,809,985
Ensembl chrNW_004624767:15,749,862...15,809,970 		JBrowse link
G Cars2 cysteinyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624793:2,126,304...2,148,619
Ensembl chrNW_004624793:2,130,608...2,148,519 		JBrowse link
glutaminyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:26869582) UniProt PMID:26869582 NCBI chrNW_004624774:5,609,623...5,673,815
Ensembl chrNW_004624774:5,609,623...5,673,791 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624730:3,123,877...3,130,787
Ensembl chrNW_004624730:3,120,958...3,130,757 		JBrowse link
glutaminyl-tRNAGln biosynthesis via transamidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gatb glutamyl-tRNA amidotransferase subunit B involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624858:3,121,443...3,208,853
Ensembl chrNW_004624858:3,121,443...3,208,904 		JBrowse link
G Gatc glutamyl-tRNA amidotransferase subunit C involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624747:13,210,001...13,220,434
Ensembl chrNW_004624747:13,210,282...13,220,328 		JBrowse link
G Qrsl1 glutaminyl-tRNA amidotransferase subunit QRSL1 involved_in IEA TreeGrafter
UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624780:15,629,167...15,664,787
Ensembl chrNW_004624780:15,628,678...15,664,651 		JBrowse link
glutamyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624782:8,698,743...8,719,064
Ensembl chrNW_004624782:8,700,195...8,719,911 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624835:3,635,829...3,695,875
Ensembl chrNW_004624835:3,635,457...3,695,909 		JBrowse link
glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gars1 glycyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19470612) MGI
InterPro		 PMID:19470612 GO_REF:0000002 NCBI chrNW_004624739:172,111...211,229
Ensembl chrNW_004624739:171,777...211,164 		JBrowse link
histidyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hars1 histidyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624743:33,424,705...33,435,767
Ensembl chrNW_004624743:33,423,342...33,435,721 		JBrowse link
G Hars2 histidyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624743:33,435,777...33,443,036
Ensembl chrNW_004624743:33,435,806...33,443,227 		JBrowse link
isoleucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iars1 isoleucyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8052601) TreeGrafter
InterPro
MGI		 PMID:8052601 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624868:4,062,938...4,168,712
Ensembl chrNW_004624868:4,063,002...4,168,715 		JBrowse link
leucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lars1 leucyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624774:5,609,623...5,673,815
Ensembl chrNW_004624774:5,609,623...5,673,791 		JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624730:75,228,638...75,335,045
Ensembl chrNW_004624730:75,228,316...75,335,052 		JBrowse link
lysyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kars1 lysyl-tRNA synthetase 1 involved_in ISO
IEA		 RGD
InterPro
TreeGrafter		 PMID:7082655 PMID:7372681 GO_REF:0000002 GO_REF:0000118 RGD:2303393 RGD:2303394 NCBI chrNW_004624746:11,337,505...11,354,950
Ensembl chrNW_004624746:11,337,529...11,353,797 		JBrowse link
methionyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mars1 methionyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624802:10,443,216...10,460,971
Ensembl chrNW_004624802:10,443,223...10,460,971 		JBrowse link
G Mars2 methionyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:15274629) UniProt PMID:15274629 NCBI chrNW_004624889:2,624,053...2,632,177
Ensembl chrNW_004624889:2,630,303...2,632,084 		JBrowse link
mitochondrial alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:21549344) BHF-UCL PMID:21549344 NCBI chrNW_004624754:15,563,878...15,573,538
Ensembl chrNW_004624754:15,563,872...15,573,536 		JBrowse link
mitochondrial asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dars2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624771:8,003,208...8,033,981
Ensembl chrNW_004624771:8,003,295...8,034,043 		JBrowse link
mitochondrial glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gars1 glycyl-tRNA synthetase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624739:172,111...211,229
Ensembl chrNW_004624739:171,777...211,164 		JBrowse link
mitochondrial seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sars2 seryl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624794:12,269,773...12,280,537
Ensembl chrNW_004624794:12,269,615...12,280,558 		JBrowse link
mitochondrial tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wars2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:14,652,874...14,735,732
Ensembl chrNW_004624772:14,654,403...14,735,315 		JBrowse link
mitochondrial tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Yars2 tyrosyl-tRNA synthetase 2 involved_in ISO (PMID:20598274) BHF-UCL PMID:20598274 NCBI chrNW_004624778:3,382,993...3,390,357
Ensembl chrNW_004624778:3,383,017...3,390,036 		JBrowse link
phenylalanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624756:19,550,198...20,016,561
Ensembl chrNW_004624756:19,550,103...19,928,538 		JBrowse link
G Farsa phenylalanyl-tRNA synthetase subunit alpha involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624901:492,673...505,815
Ensembl chrNW_004624901:492,817...505,911 		JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta involved_in IEA TreeGrafter
UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624823:2,559,757...2,627,606
Ensembl chrNW_004624823:2,559,756...2,627,606 		JBrowse link
prolyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624835:3,635,829...3,695,875
Ensembl chrNW_004624835:3,635,457...3,695,909 		JBrowse link
G Pars2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624862:5,084,676...5,093,914
Ensembl chrNW_004624862:5,087,783...5,092,422 		JBrowse link
seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sars1 seryl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624772:4,963,173...4,978,294 JBrowse link
G Sars2 seryl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624794:12,269,773...12,280,537
Ensembl chrNW_004624794:12,269,615...12,280,558 		JBrowse link
threonyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tars1 threonyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624759:21,132,104...21,154,533
Ensembl chrNW_004624759:21,132,116...21,154,620 		JBrowse link
G Tars2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624772:18,221,704...18,234,080
Ensembl chrNW_004624772:18,221,459...18,240,601 		JBrowse link
G Tars3 threonyl-tRNA synthetase 3 involved_in ISO (MGI:6164765|PMID:29579307) UniProt PMID:29579307 MGI:6164765 NCBI chrNW_004624768:3,126,637...3,183,094
Ensembl chrNW_004624768:3,126,695...3,182,133 		JBrowse link
tRNA aminoacylation for mitochondrial protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:19805282) UniProt PMID:19805282 NCBI chrNW_004624782:8,698,743...8,719,064
Ensembl chrNW_004624782:8,700,195...8,719,911 		JBrowse link
tRNA aminoacylation for protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dars2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624771:8,003,208...8,033,981
Ensembl chrNW_004624771:8,003,295...8,034,043 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004624835:3,635,829...3,695,875
Ensembl chrNW_004624835:3,635,457...3,695,909 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004624739:172,111...211,229
Ensembl chrNW_004624739:171,777...211,164 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624743:33,424,705...33,435,767
Ensembl chrNW_004624743:33,423,342...33,435,721 		JBrowse link
G Pars2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004624862:5,084,676...5,093,914
Ensembl chrNW_004624862:5,087,783...5,092,422 		JBrowse link
G Tars1 threonyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004624759:21,132,104...21,154,533
Ensembl chrNW_004624759:21,132,116...21,154,620 		JBrowse link
G Tars2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004624772:18,221,704...18,234,080
Ensembl chrNW_004624772:18,221,459...18,240,601 		JBrowse link
tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wars1 tryptophanyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624734:3,777,866...3,815,369
Ensembl chrNW_004624734:3,782,733...3,817,852 		JBrowse link
G Wars2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624772:14,652,874...14,735,732
Ensembl chrNW_004624772:14,654,403...14,735,315 		JBrowse link
tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Yars1 tyrosyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624764:15,898,648...15,933,386
Ensembl chrNW_004624764:15,898,646...15,933,400 		JBrowse link
G Yars2 tyrosyl-tRNA synthetase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624778:3,382,993...3,390,357
Ensembl chrNW_004624778:3,383,017...3,390,036 		JBrowse link
valyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vars1 valyl-tRNA synthetase 1 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624754:24,430,500...24,442,181
Ensembl chrNW_004624754:24,430,920...24,442,110 		JBrowse link
G Vars2 valyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624754:24,856,704...24,870,932
Ensembl chrNW_004624754:24,856,939...24,870,932 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9678
      primary metabolic process 8614
        amino acid metabolic process 270
          amino acid activation 42
            tRNA aminoacylation 41
              asparaginyl-tRNAAsn biosynthesis via transamidation 0
              glutaminyl-tRNAGln biosynthesis via transamidation 3
              tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
              tRNA aminoacylation for protein translation + 38
Path 2
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9678
      primary metabolic process 8614
        nucleobase-containing compound metabolic process 4588
          nucleic acid metabolic process 4133
            RNA metabolic process 3634
              tRNA metabolic process 167
                tRNA aminoacylation 41
                  asparaginyl-tRNAAsn biosynthesis via transamidation 0
                  glutaminyl-tRNAGln biosynthesis via transamidation 3
                  tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
                  tRNA aminoacylation for protein translation + 38
paths to the root