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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA aminoacylation
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Accession:GO:0043039 term browser browse the term
Definition:The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
Synonyms:exact_synonym: aminoacyl-tRNA biosynthesis;   aminoacyl-tRNA biosynthetic process;   tRNA charging


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tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,378,705...25,406,975
Ensembl chr 7:25,378,705...25,406,947 		JBrowse link
G FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr35:5,389,694...5,887,911
Ensembl chr35:5,460,664...5,948,574 		JBrowse link
G FARSA phenylalanyl-tRNA synthetase subunit alpha involved_in IEA InterPro GO_REF:0000002 NCBI chr20:49,258,827...49,267,279
Ensembl chr20:49,258,845...49,267,198 		JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 involved_in ISO (PMID:15779907), (PMID:15840810), (PMID:17997975) BHF-UCL PMID:15779907 PMID:15840810 PMID:17997975 NCBI chr27:16,139,462...16,162,701
Ensembl chr27:16,139,499...16,161,147 		JBrowse link
alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16906134) RGD
MGI
Ensembl
InterPro		 PMID:2040280 PMID:16906134 GO_REF:0000002 GO_REF:0000107 RGD:2302982 NCBI chr 5:76,288,780...76,343,262
Ensembl chr 5:76,288,782...76,343,207 		JBrowse link
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr12:12,706,043...12,718,821
Ensembl chr12:12,704,983...12,718,821 		JBrowse link
G LOC480510 alanyl-tRNA editing protein Aarsd1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:20,091,116...20,102,125 JBrowse link
G PTGES3L prostaglandin E synthase 3 like involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:20,080,611...20,085,900 JBrowse link
arginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DALRD3 DALR anticodon binding domain containing 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:40,145,239...40,148,731
Ensembl chr20:40,145,700...40,148,729
Ensembl chr20:40,145,700...40,148,729 		JBrowse link
G RARS1 arginyl-tRNA synthetase 1 involved_in ISO
IEA		 RGD
Ensembl
InterPro		 PMID:7082655 GO_REF:0000002 GO_REF:0000107 RGD:2303394 NCBI chr 4:43,237,499...43,260,738
Ensembl chr 4:43,237,499...43,260,677 		JBrowse link
G RARS2 arginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr12:46,993,787...47,047,295
Ensembl chr12:46,992,959...47,047,240 		JBrowse link
asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAB2 GRB2 associated binding protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr21:20,414,903...20,605,807
Ensembl chr21:20,277,507...20,606,736 		JBrowse link
G NARS1 asparaginyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:18,320,941...18,338,185
Ensembl chr 1:18,321,021...18,337,430 		JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr21:20,277,707...20,413,624
Ensembl chr21:20,277,507...20,606,736 		JBrowse link
aspartyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS1 aspartyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:38,690,170...38,751,360
Ensembl chr19:38,668,527...38,751,310 		JBrowse link
cysteinyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARS1 cysteinyl-tRNA synthetase 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr18:46,959,743...47,007,521
Ensembl chr18:46,959,743...47,007,460 		JBrowse link
G CARS2 cysteinyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr22:58,891,826...58,946,112
Ensembl chr22:58,902,293...58,947,558 		JBrowse link
glutaminyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARS1 leucyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:40,544,031...40,619,268
Ensembl chr 2:40,544,210...40,635,281 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:40,077,856...40,085,100
Ensembl chr20:40,078,163...40,085,099 		JBrowse link
glutaminyl-tRNAGln biosynthesis via transamidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATB glutamyl-tRNA amidotransferase subunit B involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr15:49,602,453...49,698,593
Ensembl chr15:49,603,559...49,698,535 		JBrowse link
G GATC glutamyl-tRNA amidotransferase subunit C involved_in IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr26:16,352,826...16,362,298 JBrowse link
G QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 involved_in IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr12:63,972,423...64,003,506 JBrowse link
glutamyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:22,276,189...22,299,865
Ensembl chr 6:22,276,230...22,297,428 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr38:14,754,628...14,823,626
Ensembl chr38:14,754,632...14,823,621 		JBrowse link
glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GARS1 glycyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19470612) Ensembl
MGI
InterPro		 PMID:19470612 GO_REF:0000002 GO_REF:0000107 NCBI chr14:43,308,274...43,351,999
Ensembl chr14:43,308,152...43,396,487 		JBrowse link
histidyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HARS1 histidyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:35,828,243...35,843,615
Ensembl chr 2:35,828,260...35,843,583 		JBrowse link
G HARS2 histidyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:35,843,611...35,851,257
Ensembl chr 2:35,843,706...35,850,760 		JBrowse link
isoleucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IARS1 isoleucyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8052601) MGI
Ensembl
InterPro		 PMID:8052601 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:99,045,023...99,113,865
Ensembl chr 1:99,045,102...99,113,620 		JBrowse link
G IARS2 isoleucyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr38:14,864,004...14,925,684
Ensembl chr38:14,863,998...14,925,635 		JBrowse link
leucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARS1 leucyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:40,544,031...40,619,268
Ensembl chr 2:40,544,210...40,635,281 		JBrowse link
G LARS2 leucyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:42,891,823...43,080,987
Ensembl chr20:42,892,801...43,081,197 		JBrowse link
lysyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:25,378,705...25,406,975
Ensembl chr 7:25,378,705...25,406,947 		JBrowse link
G KARS1 lysyl-tRNA synthetase 1 involved_in ISO
IEA		 RGD
Ensembl
InterPro		 PMID:7082655 PMID:7372681 GO_REF:0000002 GO_REF:0000107 RGD:2303393 RGD:2303394 NCBI chr 5:75,172,976...75,188,197
Ensembl chr 5:75,173,032...75,188,197 		JBrowse link
methionyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:1,588,503...1,606,752
Ensembl chr10:1,588,875...1,606,750 		JBrowse link
G MARS2 methionyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr37:7,149,375...7,155,318
Ensembl chr37:7,149,418...7,152,418 		JBrowse link
mitochondrial alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,706,043...12,718,821
Ensembl chr12:12,704,983...12,718,821 		JBrowse link
mitochondrial asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,378,705...25,406,975
Ensembl chr 7:25,378,705...25,406,947 		JBrowse link
mitochondrial tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G YARS2 tyrosyl-tRNA synthetase 2 involved_in ISO (PMID:20598274) BHF-UCL PMID:20598274 NCBI chr27:16,139,462...16,162,701
Ensembl chr27:16,139,499...16,161,147 		JBrowse link
phenylalanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr35:5,389,694...5,887,911
Ensembl chr35:5,460,664...5,948,574 		JBrowse link
G FARSA phenylalanyl-tRNA synthetase subunit alpha involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:49,258,827...49,267,279
Ensembl chr20:49,258,845...49,267,198 		JBrowse link
G FARSB phenylalanyl-tRNA synthetase subunit beta involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr37:28,647,114...28,716,193
Ensembl chr37:28,647,115...28,716,198 		JBrowse link
G LRRC47 leucine rich repeat containing 47 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:58,286,909...58,297,961
Ensembl chr 5:58,288,392...58,297,996 		JBrowse link
prolyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr38:14,754,628...14,823,626
Ensembl chr38:14,754,632...14,823,621 		JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:54,392,668...54,401,983
Ensembl chr 5:54,397,126...54,398,729 		JBrowse link
seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARS1 seryl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:42,584,792...42,605,201
Ensembl chr 6:42,584,798...42,605,136 		JBrowse link
G SARS2 seryl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:114,192,574...114,202,385 JBrowse link
threonyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARS1 threonyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:74,213,475...74,239,056
Ensembl chr 4:74,213,772...74,238,971 		JBrowse link
G TARS2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr17:59,681,889...59,695,747
Ensembl chr17:59,681,936...59,695,746 		JBrowse link
G TARS3 threonyl-tRNA synthetase 3 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:39,346,694...39,419,900
Ensembl chr 3:39,241,010...39,419,899 		JBrowse link
tRNA aminoacylation for mitochondrial protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,276,189...22,299,865
Ensembl chr 6:22,276,230...22,297,428 		JBrowse link
tRNA aminoacylation for protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:25,378,705...25,406,975
Ensembl chr 7:25,378,705...25,406,947 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr38:14,754,628...14,823,626
Ensembl chr38:14,754,632...14,823,621 		JBrowse link
G GARS1 glycyl-tRNA synthetase 1 involved_in IEA UniProt
Ensembl		 GO_REF:0000107 GO_REF:0000117 NCBI chr14:43,308,274...43,351,999
Ensembl chr14:43,308,152...43,396,487 		JBrowse link
G HARS1 histidyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:35,828,243...35,843,615
Ensembl chr 2:35,828,260...35,843,583 		JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr21:20,277,707...20,413,624
Ensembl chr21:20,277,507...20,606,736 		JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117 NCBI chr 5:54,392,668...54,401,983
Ensembl chr 5:54,397,126...54,398,729 		JBrowse link
G TARS1 threonyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 4:74,213,475...74,239,056
Ensembl chr 4:74,213,772...74,238,971 		JBrowse link
G TARS2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117 NCBI chr17:59,681,889...59,695,747
Ensembl chr17:59,681,936...59,695,746 		JBrowse link
G TARS3 threonyl-tRNA synthetase 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr 3:39,346,694...39,419,900
Ensembl chr 3:39,241,010...39,419,899 		JBrowse link
G YARS1 tyrosyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:68,535,402...68,566,197
Ensembl chr 2:68,535,447...68,565,439 		JBrowse link
tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WARS1 tryptophanyl-tRNA synthetase 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:68,610,105...68,644,616
Ensembl chr 8:68,610,090...68,643,467 		JBrowse link
G WARS2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr17:56,229,175...56,322,688
Ensembl chr17:56,229,769...56,322,638 		JBrowse link
tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G YARS1 tyrosyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:68,535,402...68,566,197
Ensembl chr 2:68,535,447...68,565,439 		JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr27:16,139,462...16,162,701
Ensembl chr27:16,139,499...16,161,147 		JBrowse link
valyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VARS1 valyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:1,254,954...1,269,242
Ensembl chr12:1,254,952...1,269,208 		JBrowse link
G VARS2 valyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr12:681,638...694,154
Ensembl chr12:680,484...693,913 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    metabolic process 10855
      primary metabolic process 9582
        amino acid metabolic process 292
          amino acid activation 47
            tRNA aminoacylation 46
              asparaginyl-tRNAAsn biosynthesis via transamidation 0
              glutaminyl-tRNAGln biosynthesis via transamidation 3
              tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
              tRNA aminoacylation for protein translation + 43
Path 2
Term Annotations click to browse term
  biological_process 17068
    metabolic process 10855
      primary metabolic process 9582
        nucleobase-containing compound metabolic process 5112
          nucleic acid metabolic process 4567
            RNA metabolic process 4039
              tRNA metabolic process 172
                tRNA aminoacylation 46
                  asparaginyl-tRNAAsn biosynthesis via transamidation 0
                  glutaminyl-tRNAGln biosynthesis via transamidation 3
                  tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
                  tRNA aminoacylation for protein translation + 43
paths to the root