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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA aminoacylation
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Accession:GO:0043039 term browser browse the term
Definition:The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
Synonyms:exact_synonym: aminoacyl-tRNA biosynthesis;   aminoacyl-tRNA biosynthetic process;   tRNA charging

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tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dars2 aspartyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:15779907), (PMID:17384640) BHF-UCL PMID:15779907 PMID:17384640 NCBI chrNW_004955406:13,964,087...13,991,691
Ensembl chrNW_004955406:13,964,087...13,991,691 		JBrowse link
G Yars2 tyrosyl-tRNA synthetase 2 involved_in ISO (PMID:15779907), (PMID:15840810), (PMID:17997975) BHF-UCL PMID:15779907 PMID:15840810 PMID:17997975 NCBI chrNW_004955505:3,004,084...3,011,003
Ensembl chrNW_004955505:3,004,146...3,010,735 		JBrowse link
alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:16906134)
(PMID:33909043)
(MGI:5905209|PMID:27622773)
(PMID:27622773), (PMID:28493438)		 RGD
MGI
UniProt		 PMID:2040280 PMID:16906134 PMID:27622773 PMID:28493438 PMID:33909043 MGI:5905209 RGD:2302982 NCBI chrNW_004955484:3,090,678...3,115,224
Ensembl chrNW_004955484:3,089,235...3,115,230 		JBrowse link
arginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rars1 arginyl-tRNA synthetase 1 involved_in ISO (MGI:3055639|PMID:12060739)
(PMID:25288775)		 RGD
CAFA
UniProt		 PMID:7082655 PMID:12060739 PMID:25288775 MGI:3055639 RGD:2303394 NCBI chrNW_004955408:21,536,426...21,574,683 JBrowse link
asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nars1 asparaginyl-tRNA synthetase 1 involved_in ISO (PMID:9421509) UniProt PMID:9421509 NCBI chrNW_004955402:41,947,592...41,967,136
Ensembl chrNW_004955402:41,946,098...41,967,644 		JBrowse link
cysteinyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cars1 cysteinyl-tRNA synthetase 1 involved_in ISO (PMID:10908348), (PMID:11347887), (PMID:17303165) UniProt PMID:10908348 PMID:11347887 PMID:17303165 NCBI chrNW_004955422:14,685,356...14,738,420
Ensembl chrNW_004955422:14,682,178...14,738,428 		JBrowse link
G Cars2 cysteinyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:29079736) UniProt PMID:29079736 NCBI chrNW_004955404:2,008,980...2,027,672
Ensembl chrNW_004955404:1,996,400...2,027,563 		JBrowse link
glutaminyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:26869582) UniProt PMID:26869582 NCBI chrNW_004955415:7,923,292...7,983,757
Ensembl chrNW_004955415:7,923,059...7,983,757 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO (PMID:24656866), (PMID:26869582) UniProt PMID:24656866 PMID:26869582 NCBI chrNW_004955532:1,093,444...1,100,591
Ensembl chrNW_004955532:1,092,125...1,100,603 		JBrowse link
glutaminyl-tRNAGln biosynthesis via transamidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gatb glutamyl-tRNA amidotransferase subunit B involved_in ISO (PMID:19805282) UniProt PMID:19805282 NCBI chrNW_004955471:6,230,027...6,313,655
Ensembl chrNW_004955471:6,230,027...6,313,706 		JBrowse link
G Gatc glutamyl-tRNA amidotransferase subunit C involved_in ISO (PMID:19805282) UniProt PMID:19805282 NCBI chrNW_004955455:11,184,400...11,195,398
Ensembl chrNW_004955455:11,184,693...11,195,340 		JBrowse link
G Qrsl1 glutaminyl-tRNA amidotransferase subunit QRSL1 involved_in ISO (PMID:19805282) UniProt PMID:19805282 NCBI chrNW_004955411:31,950,727...31,981,522
Ensembl chrNW_004955411:31,950,828...31,981,468 		JBrowse link
glutamyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:19805282) UniProt PMID:19805282 NCBI chrNW_004955493:2,083,272...2,113,403
Ensembl chrNW_004955493:2,090,940...2,113,843 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in ISO (PMID:3290852) UniProt PMID:3290852 NCBI chrNW_004955520:3,550,558...3,606,015
Ensembl chrNW_004955520:3,550,558...3,606,697 		JBrowse link
glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gars1 glycyl-tRNA synthetase 1 acts_upstream_of_or_within ISO (PMID:19470612) MGI PMID:19470612 NCBI chrNW_004955410:31,778,654...31,819,287
Ensembl chrNW_004955410:31,779,543...31,819,113 		JBrowse link
histidyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hars1 histidyl-tRNA synthetase 1 involved_in ISO (PMID:29235198) UniProt PMID:29235198 NCBI chrNW_004955418:19,346...30,514
Ensembl chrNW_004955418:19,346...30,514 		JBrowse link
G Hars2 histidyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:21464306) WB PMID:21464306 NCBI chrNW_004955418:12,550...19,282
Ensembl chrNW_004955418:12,550...19,282 		JBrowse link
isoleucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iars1 isoleucyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:8052601)
(MGI:3055639|PMID:12060739)		 MGI
CAFA		 PMID:8052601 PMID:12060739 MGI:3055639 NCBI chrNW_004955515:5,506,064...5,558,075
Ensembl chrNW_004955515:5,498,231...5,557,629 		JBrowse link
leucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (MGI:3055639|PMID:12060739)
(PMID:25051973)		 CAFA
UniProt		 PMID:12060739 PMID:25051973 MGI:3055639 NCBI chrNW_004955415:7,923,292...7,983,757
Ensembl chrNW_004955415:7,923,059...7,983,757 		JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:10684970) HGNC PMID:10684970 NCBI chrNW_004955420:26,342,129...26,446,959
Ensembl chrNW_004955420:26,343,649...26,441,736 		JBrowse link
lysyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kars1 lysyl-tRNA synthetase 1 involved_in ISO (PMID:10952987), (PMID:23159739), (PMID:9278442)
PMID:6315704		 RGD
UniProt		 PMID:6315704 PMID:7082655 PMID:7372681 PMID:9278442 PMID:10952987 More... RGD:12911009 RGD:2303393 RGD:2303394 NCBI chrNW_004955484:1,924,523...1,939,777
Ensembl chrNW_004955484:1,924,523...1,940,552 		JBrowse link
methionyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mars1 methionyl-tRNA synthetase 1 involved_in ISO (PMID:11714285)
(PMID:33909043)
(MGI:3055639|PMID:12060739)		 UniProt
CAFA		 PMID:11714285 PMID:12060739 PMID:33909043 MGI:3055639 NCBI chrNW_004955458:5,215,853...5,233,037
Ensembl chrNW_004955458:5,215,853...5,233,037 		JBrowse link
G Mars2 methionyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:15274629) UniProt PMID:15274629 NCBI chrNW_004955403:2,967,541...2,970,443
Ensembl chrNW_004955403:2,968,574...2,970,387 		JBrowse link
mitochondrial alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:21549344) BHF-UCL PMID:21549344 NCBI chrNW_004955437:9,915,371...9,924,886
Ensembl chrNW_004955437:9,913,867...9,924,886 		JBrowse link
mitochondrial asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dars2 aspartyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:23275545) UniProt PMID:23275545 NCBI chrNW_004955406:13,964,087...13,991,691
Ensembl chrNW_004955406:13,964,087...13,991,691 		JBrowse link
mitochondrial tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Yars2 tyrosyl-tRNA synthetase 2 involved_in ISO (PMID:20598274) BHF-UCL PMID:20598274 NCBI chrNW_004955505:3,004,084...3,011,003
Ensembl chrNW_004955505:3,004,146...3,010,735 		JBrowse link
phenylalanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:10329163) UniProt PMID:10329163 NCBI chrNW_004955465:7,878,115...8,345,749
Ensembl chrNW_004955465:7,877,824...8,241,742 		JBrowse link
G Farsa phenylalanyl-tRNA synthetase subunit alpha involved_in ISO (PMID:20223217) UniProt PMID:20223217 NCBI chrNW_004955415:31,972,888...31,981,424
Ensembl chrNW_004955415:31,968,980...31,981,424 		JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta involved_in ISO (PMID:20223217) UniProt PMID:20223217 NCBI chrNW_004955453:11,176,481...11,237,243
Ensembl chrNW_004955453:11,176,432...11,240,780 		JBrowse link
prolyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in ISO (PMID:24100331)
(MGI:3055639|PMID:12060739)		 UniProt
CAFA		 PMID:12060739 PMID:24100331 MGI:3055639 NCBI chrNW_004955520:3,550,558...3,606,015
Ensembl chrNW_004955520:3,550,558...3,606,697 		JBrowse link
seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sars1 seryl-tRNA synthetase 1 involved_in ISO (PMID:24095058), (PMID:36041817)
(PMID:28236339), (PMID:34570399)		 UniProt PMID:24095058 PMID:28236339 PMID:34570399 PMID:36041817 NCBI chrNW_004955435:12,642,485...12,659,833
Ensembl chrNW_004955435:12,641,776...12,660,682 		JBrowse link
threonyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tars1 threonyl-tRNA synthetase 1 involved_in ISO (PMID:25824639)
(MGI:3055639|PMID:12060739), (MGI:6164765|PMID:29579307)		 UniProt PMID:12060739 PMID:25824639 PMID:29579307 MGI:3055639 MGI:6164765 NCBI chrNW_004955426:19,086,817...19,110,609
Ensembl chrNW_004955426:19,087,389...19,110,609 		JBrowse link
G Tars3 threonyl-tRNA synthetase 3 involved_in ISO (MGI:6164765|PMID:29579307) UniProt PMID:29579307 MGI:6164765 NCBI chrNW_004955416:28,509,229...28,554,050
Ensembl chrNW_004955416:28,510,217...28,553,979 		JBrowse link
tRNA aminoacylation for mitochondrial protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:19805282) UniProt PMID:19805282 NCBI chrNW_004955493:2,083,272...2,113,403
Ensembl chrNW_004955493:2,090,940...2,113,843 		JBrowse link
tRNA aminoacylation for protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gars1 glycyl-tRNA synthetase 1 involved_in ISO (PMID:28675565) UniProt PMID:28675565 NCBI chrNW_004955410:31,778,654...31,819,287
Ensembl chrNW_004955410:31,779,543...31,819,113 		JBrowse link
tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wars1 tryptophanyl-tRNA synthetase 1 involved_in ISO (MGI:3055639|PMID:12060739), (PMID:19941862) MGI PMID:12060739 PMID:19941862 MGI:3055639 NCBI chrNW_004955438:21,414,878...21,445,417
Ensembl chrNW_004955438:21,414,815...21,445,042 		JBrowse link
tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Yars1 tyrosyl-tRNA synthetase 1 involved_in ISO (PMID:25533949) UniProt PMID:25533949 NCBI chrNW_004955452:11,046,047...11,078,016
Ensembl chrNW_004955452:11,046,047...11,078,016 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7924
      primary metabolic process 6989
        amino acid metabolic process 209
          amino acid activation 32
            tRNA aminoacylation 31
              asparaginyl-tRNAAsn biosynthesis via transamidation 0
              glutaminyl-tRNAGln biosynthesis via transamidation 3
              tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
              tRNA aminoacylation for protein translation + 28
Path 2
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7924
      primary metabolic process 6989
        nucleobase-containing compound metabolic process 3897
          nucleic acid metabolic process 3517
            RNA metabolic process 3058
              tRNA metabolic process 116
                tRNA aminoacylation 31
                  asparaginyl-tRNAAsn biosynthesis via transamidation 0
                  glutaminyl-tRNAGln biosynthesis via transamidation 3
                  tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
                  tRNA aminoacylation for protein translation + 28
paths to the root