ONTOLOGY REPORT - ANNOTATIONS
Term: tRNA aminoacylation
Accession: GO:0043039
browse the term
Definition: The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
Synonyms: exact_synonym: aminoacyl-tRNA biosynthesis; aminoacyl-tRNA biosynthetic process; tRNA charging
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DARS2
aspartyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:149,342,301...149,375,979
Ensembl chr 1:153,045,886...153,080,461
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YARS2
tyrosyl-tRNA synthetase 2
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr12:53,463,086...53,493,352
Ensembl chr12:56,065,505...56,076,026
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AARS1
alanyl-tRNA synthetase 1
involved_in acts_upstream_of_or_within
ISO IEA
(PMID:16906134)
RGD TreeGrafter MGI InterPro Ensembl
PMID:2040280 PMID:16906134
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2302982
NCBI chr16:54,727,601...54,763,458
Ensembl chr16:70,086,735...70,121,902
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AARS2
alanyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 6:43,895,255...43,909,347
Ensembl chr 6:45,176,773...45,191,505
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AARSD1
alanyl-tRNA synthetase domain containing 1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr17:14,358,207...14,372,668
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PTGES3L
prostaglandin E synthase 3 like
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr17:14,344,870...14,355,271
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DALRD3
DALR anticodon binding domain containing 3
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 3:48,940,126...48,945,717
Ensembl chr 3:50,021,669...50,024,522
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RARS1
arginyl-tRNA synthetase 1
involved_in
ISO IEA
RGD TreeGrafter InterPro Ensembl
PMID:7082655
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2303394
NCBI chr 5:163,851,644...163,884,787
Ensembl chr 5:170,616,819...170,649,655
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RARS2
arginyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 6:85,391,061...85,466,888
Ensembl chr 6:88,665,543...88,741,371
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NARS1
asparaginyl-tRNA synthetase 1
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr18:50,991,047...51,011,628
Ensembl chr18:54,326,053...54,346,454
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NARS2
asparaginyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr11:73,496,423...73,634,623
Ensembl chr11:77,117,668...77,255,037
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DARS1
aspartyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr2B:23,876,931...23,956,032
Ensembl chr2B:139,977,483...140,056,836
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DARS2
aspartyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 1:149,342,301...149,375,979
Ensembl chr 1:153,045,886...153,080,461
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CARS1
cysteinyl-tRNA synthetase 1
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr11:3,026,787...3,083,170
Ensembl chr11:3,053,551...3,109,509
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CARS2
cysteinyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr13:91,776,774...91,843,262
Ensembl chr13:110,892,948...110,957,000
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LARS1
leucyl-tRNA synthetase 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:141,562,798...141,631,388
Ensembl chr 5:147,578,042...147,646,834
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QARS1
glutaminyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112
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USP19
ubiquitin specific peptidase 19
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112
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GATB
glutamyl-tRNA amidotransferase subunit B
involved_in
IEA
UniProt Ensembl TreeGrafter
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr 4:144,005,127...144,095,552
Ensembl chr 4:155,657,600...155,747,679
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GATC
glutamyl-tRNA amidotransferase subunit C
involved_in
IEA
UniProt TreeGrafter Ensembl
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr12:118,028,042...118,045,403
Ensembl chr12:121,402,532...121,419,628
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QRSL1
glutaminyl-tRNA amidotransferase subunit QRSL1
involved_in
IEA
UniProt TreeGrafter Ensembl
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr 6:104,444,646...104,481,732
Ensembl chr 6:108,315,270...108,353,505
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EARS2
glutamyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr16:14,552,664...14,588,022
Ensembl chr16:23,774,123...23,809,873
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EPRS1
glutamyl-prolyl-tRNA synthetase 1
involved_in
IEA
InterPro Ensembl
GO_REF:0000002 GO_REF:0000107
NCBI chr 1:195,537,319...195,618,257
Ensembl chr 1:200,575,259...200,656,197
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GARS1
glycyl-tRNA synthetase 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:19470612)
Ensembl MGI InterPro
PMID:19470612
GO_REF:0000002 GO_REF:0000107
NCBI chr 7:31,208,351...31,247,841
Ensembl chr 7:31,329,456...31,368,582
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HARS1
histidyl-tRNA synthetase 1
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 5:136,038,575...136,056,400
Ensembl chr 5:142,154,552...142,172,371
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LOC100969951
histidine--tRNA ligase, mitochondrial
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 5:136,056,060...136,065,588
Ensembl chr 5:142,172,081...142,179,950
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IARS1
isoleucyl-tRNA synthetase 1
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:8052601)
MGI TreeGrafter Ensembl InterPro
PMID:8052601
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 9:63,332,030...63,415,567
Ensembl chr 9:91,406,008...91,489,167
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IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 1:195,666,995...195,720,661
Ensembl chr 1:200,703,711...200,757,648
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LARS1
leucyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 5:141,562,798...141,631,388
Ensembl chr 5:147,578,042...147,646,834
G
LARS2
leucyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 3:45,296,129...45,455,836
Ensembl chr 3:46,405,636...46,564,994
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KARS1
lysyl-tRNA synthetase 1
involved_in
ISO IEA
RGD TreeGrafter Ensembl InterPro
PMID:7082655 PMID:7372681
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2303393 RGD:2303394
NCBI chr16:56,196,867...56,216,909
Ensembl chr16:75,545,002...75,565,043
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MARS1
methionyl-tRNA synthetase 1
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr12:31,410,231...31,438,015
Ensembl chr12:31,668,708...31,693,839
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MARS2
methionyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr2B:84,954,833...84,957,871
Ensembl chr2B:202,847,478...202,849,259
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AARS2
alanyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:43,895,255...43,909,347
Ensembl chr 6:45,176,773...45,191,505
G
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:149,342,301...149,375,979
Ensembl chr 1:153,045,886...153,080,461
G
GARS1
glycyl-tRNA synthetase 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 7:31,208,351...31,247,841
Ensembl chr 7:31,329,456...31,368,582
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SARS2
seryl-tRNA synthetase 2, mitochondrial
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr19:36,015,983...36,037,404
Ensembl chr19:44,565,214...44,568,594 Ensembl chr19:44,565,214...44,568,594 Ensembl chr19:44,565,214...44,568,594
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WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 1:83,405,595...83,515,718
Ensembl chr 1:118,402,385...118,516,099
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YARS2
tyrosyl-tRNA synthetase 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr12:53,463,086...53,493,352
Ensembl chr12:56,065,505...56,076,026
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FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 6:5,096,453...5,608,362
Ensembl chr 6:5,387,291...5,792,749
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FARSA
phenylalanyl-tRNA synthetase subunit alpha
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr19:12,484,607...12,496,160
Ensembl chr19:13,227,193...13,238,244
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FARSB
phenylalanyl-tRNA synthetase subunit beta
involved_in
IEA
Ensembl TreeGrafter UniProt InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118
NCBI chr2B:109,813,000...109,897,159
Ensembl chr2B:228,394,238...228,478,345
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LRRC47
leucine rich repeat containing 47
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 1:2,451,747...2,468,043
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EPRS1
glutamyl-prolyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 1:195,537,319...195,618,257
Ensembl chr 1:200,575,259...200,656,197
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PARS2
prolyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 1:54,032,594...54,040,274
Ensembl chr 1:55,622,726...55,624,750
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SARS1
seryl-tRNA synthetase 1
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 1:111,590,850...111,615,068
Ensembl chr 1:110,755,054...110,779,704
G
SARS2
seryl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr19:36,015,983...36,037,404
Ensembl chr19:44,565,214...44,568,594 Ensembl chr19:44,565,214...44,568,594 Ensembl chr19:44,565,214...44,568,594
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TARS1
threonyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 5:76,874,096...76,901,208
Ensembl chr 5:82,256,706...82,286,179
G
TARS2
threonyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 1:125,832,693...125,852,918
Ensembl chr 1:129,480,824...129,501,639
G
TARS3
threonyl-tRNA synthetase 3
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr15:80,394,050...80,463,568
Ensembl chr15:99,667,608...99,737,300
G
EARS2
glutamyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr16:14,552,664...14,588,022
Ensembl chr16:23,774,123...23,809,873
G
CARS2
cysteinyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr13:91,776,774...91,843,262
Ensembl chr13:110,892,948...110,957,000
G
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 1:149,342,301...149,375,979
Ensembl chr 1:153,045,886...153,080,461
G
EPRS1
glutamyl-prolyl-tRNA synthetase 1
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chr 1:195,537,319...195,618,257
Ensembl chr 1:200,575,259...200,656,197
G
GARS1
glycyl-tRNA synthetase 1
involved_in
IEA
Ensembl UniProt
GO_REF:0000107 GO_REF:0000117
NCBI chr 7:31,208,351...31,247,841
Ensembl chr 7:31,329,456...31,368,582
G
HARS1
histidyl-tRNA synthetase 1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 5:136,038,575...136,056,400
Ensembl chr 5:142,154,552...142,172,371
G
NARS2
asparaginyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr11:73,496,423...73,634,623
Ensembl chr11:77,117,668...77,255,037
G
PARS2
prolyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chr 1:54,032,594...54,040,274
Ensembl chr 1:55,622,726...55,624,750
G
QARS1
glutaminyl-tRNA synthetase 1
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112
G
TARS1
threonyl-tRNA synthetase 1
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chr 5:76,874,096...76,901,208
Ensembl chr 5:82,256,706...82,286,179
G
TARS2
threonyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chr 1:125,832,693...125,852,918
Ensembl chr 1:129,480,824...129,501,639
G
TARS3
threonyl-tRNA synthetase 3
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chr15:80,394,050...80,463,568
Ensembl chr15:99,667,608...99,737,300
G
USP19
ubiquitin specific peptidase 19
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112
G
WARS1
tryptophanyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr14:80,954,852...80,996,316
Ensembl chr14:100,268,845...100,310,662
G
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr 1:83,405,595...83,515,718
Ensembl chr 1:118,402,385...118,516,099
G
YARS1
tyrosyl-tRNA synthetase 1
involved_in
IEA
InterPro Ensembl
GO_REF:0000002 GO_REF:0000107
NCBI chr 1:32,068,202...32,108,664
Ensembl chr 1:33,232,905...33,294,558
G
YARS2
tyrosyl-tRNA synthetase 2
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr12:53,463,086...53,493,352
Ensembl chr12:56,065,505...56,076,026
G
VARS1
valyl-tRNA synthetase 1
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 6:31,438,663...31,456,926
Ensembl chr 6:32,325,931...32,343,276
G
VARS2
valyl-tRNA synthetase 2, mitochondrial
involved_in
IEA
InterPro TreeGrafter
GO_REF:0000002 GO_REF:0000118
NCBI chr 6:30,659,346...30,671,678
Ensembl chr 6:31,527,372...31,539,814
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all