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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of macrophage activation
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Accession:GO:0043030 term browser browse the term
Definition:Any process that modulates the frequency or rate of macrophage activation.
Synonyms:exact_synonym: regulation of macrophage polarization



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regulation of macrophage activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd84 CD84 molecule involved_in ISO (MGI:5700297|PMID:20628063) RGD PMID:20628063 MGI:5700297 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in ISO (MGI:6378134|PMID:30595385) RGD PMID:30595385 MGI:6378134 NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28471450) RGD PMID:28471450 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743
JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming acts_upstream_of_or_within ISO MGI:5576290 (MGI:5554612|PMID:24317696) RGD PMID:24317696 MGI:5554612 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
JBrowse link
G Myo18a myosin XVIIIa involved_in ISO
IEA
(PMID:25965346)
(MGI:5810252|PMID:25965346)
GO_REF:0000107
RGD
Ensembl
PMID:25965346 GO_REF:0000107 MGI:5810252 NCBI chr10:62,654,218...62,755,464
Ensembl chr10:62,654,281...62,755,468
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO (PMID:28471450) RGD PMID:28471450 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783
JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO
GO_REF:0000107
(PMID:18511424)
Ensembl
RGD
PMID:18511424 GO_REF:0000107 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g5 phospholipase A2, group V acts_upstream_of_or_within ISO MGI:3042209 (MGI:5605113|PMID:24910243) RGD PMID:24910243 MGI:5605113 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO MGI:1857035 (MGI:50752|PMID:1565842) RGD PMID:1565842 MGI:50752 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Shpk sedoheptulokinase involved_in ISO (MGI:5428058|PMID:22682222) RGD PMID:22682222 MGI:5428058 NCBI chr10:57,817,551...57,841,981
Ensembl chr10:57,817,629...57,841,980
JBrowse link
G Slc7a2 solute carrier family 7 member 2 involved_in ISO (MGI:3774232|PMID:16670299) RGD PMID:16670299 MGI:3774232 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:2389489 (MGI:3664828|PMID:17035541) RGD PMID:17035541 MGI:3664828 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
negative regulation of macrophage activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrf5 adhesion G protein-coupled receptor F5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5547987 (MGI:5644084|PMID:25778400)
Ensembl
RGD
PMID:25778400 GO_REF:0000107 MGI:5644084 NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968
JBrowse link
G Bpi bactericidal/permeability-increasing protein involved_in IBA
ISO
PMID:21873635
(PMID:8409400)
RGD PMID:8409400 PMID:21873635 RGD:13792537 NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221
JBrowse link
G Cd200 Cd200 molecule involved_in IEA
ISO
GO_REF:0000002
(MGI:1927692|PMID:11099416)
InterPro
RGD
PMID:11099416 GO_REF:0000002 MGI:1927692 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Il4 interleukin 4 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:20623539 PMID:21873635 RGD:5128562, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Lrfn5 leucine rich repeat and fibronectin type III domain containing 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:6140757|PMID:27152329)
UniProt
RGD
PMID:27152329 GO_REF:0000024 MGI:6140757 NCBI chr 6:79,466,403...79,822,821
Ensembl chr 6:79,467,961...79,822,815
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:5009771|PMID:21187453)
Ensembl
RGD
PMID:21187453 GO_REF:0000107 MGI:5009771 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Tff2 trefoil factor 2 acts_upstream_of_or_within ISO MGI:2179101 (MGI:3694595|PMID:17101660) RGD PMID:17101660 MGI:3694595 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619
JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212
JBrowse link
negative regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5910746 (MGI:5904382|PMID:28251676)
RGD PMID:28251676 PMID:21873635 MGI:5904382, RGD:13792537 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IDA PMID:19627440 ARUK-UCL PMID:19627440 RGD:13673772 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Grn granulin precursor involved_in ISS
ISO
GO_REF:0000024
(MGI:5440302|PMID:23041626)
UniProt
RGD
PMID:23041626 GO_REF:0000024 MGI:5440302 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (MGI:4415751|PMID:20005821)
Ensembl
RGD
PMID:20005821 GO_REF:0000107 MGI:4415751 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6283959|PMID:30792350)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30792350 GO_REF:0000024 GO_REF:0000107 MGI:6283959 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO RNAcentral:URS000024A59E_10090 (MGI:6270781|PMID:30412727) RGD PMID:30412727 MGI:6270781 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Syt11 synaptotagmin 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:5913303|PMID:28686317)
UniProt
RGD
PMID:28686317 GO_REF:0000024 MGI:5913303 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5621218|PMID:25595455)
RGD PMID:25595455 PMID:21873635 MGI:5621218, RGD:13792537 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019
JBrowse link
positive regulation of macrophage activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO (MGI:5004747|PMID:21460847) RGD PMID:21460847 MGI:5004747 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha involved_in IEA
ISO
GO_REF:0000107
(MGI:6189371|PMID:21131957)
Ensembl
RGD
PMID:21131957 GO_REF:0000107 MGI:6189371 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (MGI:5490210|PMID:22383698) RGD PMID:22383698 MGI:5490210 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO UniProtKB:O08573 (MGI:4839671|PMID:20937702) RGD PMID:20937702 MGI:4839671 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:17164250) RGD PMID:17164250 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il10 interleukin 10 IDA RGD PMID:25837415 RGD:11049473 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 involved_in ISO (MGI:4430159|PMID:19841166) RGD PMID:19841166 MGI:4430159 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:4430159|PMID:19841166)
Ensembl
RGD
PMID:19841166 GO_REF:0000107 MGI:4430159 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:19841166)
(MGI:4430159|PMID:19841166)
(MGI:6414704|PMID:26936882)
GO_REF:0000107
RGD
Ensembl
PMID:19841166 PMID:26936882 GO_REF:0000107 MGI:4430159 MGI:6414704 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4r interleukin 4 receptor involved_in ISO (MGI:4430159|PMID:19841166) RGD PMID:19841166 MGI:4430159 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:18443593 RGD:2293336 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kars lysyl-tRNA synthetase involved_in IBA
ISO
PMID:21873635
(PMID:15851690)
RGD PMID:15851690 PMID:21873635 RGD:13792537 NCBI chr19:39,957,846...39,976,886
Ensembl chr19:39,957,846...39,977,632
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in IDA
IBA
ISO
IEA
PMID:21873635
(PMID:8409400)
GO_REF:0000107
RGD
Ensembl
PMID:8409400 PMID:10733550 PMID:21873635 GO_REF:0000107, RGD:9685188, RGD:13792537 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q8VIM0 (MGI:4839671|PMID:20937702) RGD PMID:20937702 MGI:4839671 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in IEA
ISO
GO_REF:0000107
(MGI:1100762|PMID:9403692), (MGI:1100763|PMID:9403693)
Ensembl
RGD
PMID:9403692 PMID:9403693 GO_REF:0000107 MGI:1100762 MGI:1100763 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18757424) RGD PMID:18757424 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:Q9Y2C9 (MGI:4438693|PMID:20037584)
Ensembl
RGD
PMID:20037584 GO_REF:0000107 MGI:4438693 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:O00206 (MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:4438693 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) RGD PMID:16633345 MGI:3656197 NCBI chr14:76,228,283...76,246,609
Ensembl chr14:76,228,371...76,275,265
JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (MGI:2450811|PMID:12645935) RGD PMID:12645935 MGI:2450811 NCBI chr 1:1,694,255...1,716,160 JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA
(PMID:18174455)
GO_REF:0000107
RGD
Ensembl
PMID:18174455 GO_REF:0000107 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
positive regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO (MGI:5904382|PMID:28251676) RGD PMID:28251676 MGI:5904382 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:22302802 RGD:13462052 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IEA
ISO
GO_REF:0000107
(MGI:6201889|PMID:25049354)
Ensembl
RGD
PMID:25049354 GO_REF:0000107 MGI:6201889 NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5621218|PMID:25595455)
RGD PMID:25595455 PMID:21873635 MGI:5621218, RGD:13792537 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IBA
ISO
PMID:21873635
(MGI:5606096|PMID:24990881), (MGI:6284411|PMID:29752066), (MGI:6304666|PMID:25631124), (MGI:6313424|PMID:30617257), (MGI:6391511|PMID:31370707)
(PMID:24990881)
RGD PMID:24990881 PMID:25631124 PMID:29752066 PMID:30617257 PMID:31370707 More... MGI:5606096 MGI:6284411 MGI:6304666 MGI:6313424 MGI:6391511, RGD:13792537 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:19118186) RGD PMID:19118186 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774
JBrowse link
regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase IMP RGD PMID:28007901 RGD:12879399 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6158194|PMID:29662056)
UniProt
RGD
PMID:29662056 GO_REF:0000024 MGI:6158194 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    immune system process 2805
      leukocyte activation 1070
        regulation of leukocyte activation 704
          regulation of macrophage activation 57
            negative regulation of macrophage activation + 16
            positive regulation of macrophage activation + 28
            regulation of microglial cell activation + 16
Path 2
Term Annotations click to browse term
  biological_process 19504
    biological regulation 13513
      regulation of biological process 12770
        regulation of cellular process 12230
          regulation of cell activation 751
            regulation of leukocyte activation 704
              regulation of macrophage activation 57
                negative regulation of macrophage activation + 16
                positive regulation of macrophage activation + 28
                regulation of microglial cell activation + 16
paths to the root