Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:NADPH oxidase complex
go back to main search page
Accession:GO:0043020 term browser browse the term
Definition:A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
Synonyms:narrow_synonym: flavocytochrome b558
 related_synonym: respiratory-burst oxidase


show annotations for term's descendants           Sort by:
 
NADPH oxidase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain part_of
colocalizes_with
IDA
ISO
IBA
IMP
(MGI:5568138|PMID:24739962)
(PMID:1763037), (PMID:3305576)
PMID:21873635
PMID:8798532
(PMID:22423966)
RGD PMID:1763037 PMID:3305576 PMID:22423966 PMID:24739962, PMID:15322091, PMID:21873635, PMID:8798532, PMID:12241540 MGI:5568138, RGD:1580287, RGD:13792537, RGD:2317869, RGD:2291907 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain part_of IDA
ISO
IBA
(MGI:5568138|PMID:24739962)
PMID:21873635
(PMID:3305576)
RGD PMID:3305576 PMID:24739962, PMID:15322091, PMID:21873635, PMID:12241540 MGI:5568138, RGD:1580287, RGD:13792537, RGD:2291907 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Duox1 dual oxidase 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Duox2 dual oxidase 2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 part_of IDA
ISO
(PMID:2550933), (PMID:8280052) RGD PMID:2550933 PMID:8280052, PMID:12241540 RGD:2291907 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 part_of ISO (PMID:8280052) RGD PMID:8280052 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 part_of ISO
IBA
(PMID:8280052)
PMID:21873635
RGD PMID:8280052, PMID:21873635 RGD:13792537 NCBI chr 7:119,481,711...119,499,426
Ensembl chr 7:119,482,272...119,499,425
JBrowse link
G Nox1 NADPH oxidase 1 part_of IDA
IBA
ISO
IEA
PMID:21873635
(PMID:16636067)
GO_REF:0000107
RGD
Ensembl
PMID:16636067, PMID:15322091, PMID:21873635 GO_REF:0000107, RGD:1580287, RGD:13792537 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nox3 NADPH oxidase 3 part_of IBA
ISO
PMID:21873635
(MGI:3709963|PMID:17140397)
RGD PMID:17140397, PMID:21873635 MGI:3709963, RGD:13792537 NCBI chr 1:44,550,994...44,615,760
Ensembl chr 1:44,550,994...44,615,760
JBrowse link
G Nox4 NADPH oxidase 4 part_of IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:15322091, PMID:21873635 RGD:1580287, RGD:13792537 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Noxa1 NADPH oxidase activator 1 part_of ISO (PMID:16636067) RGD PMID:16636067 NCBI chr 3:2,299,676...2,309,491
Ensembl chr 3:2,299,691...2,309,179
JBrowse link
G Noxo1 NADPH oxidase organizer 1 part_of ISO (PMID:16636067) RGD PMID:16636067 NCBI chr10:14,062,331...14,066,918
Ensembl chr10:14,062,331...14,066,918
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20126
    protein-containing complex 6038
      catalytic complex 1420
        oxidoreductase complex 137
          NADPH oxidase complex 12
Path 2
Term Annotations click to browse term
  cellular_component 20126
    cellular anatomical entity 19825
      membrane 10001
        intrinsic component of membrane 6769
          intrinsic component of plasma membrane 1425
            integral component of plasma membrane 1344
              NADPH oxidase complex 12
paths to the root