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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasmic sequestering of transcription factor
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Accession:GO:0042994 term browser browse the term
Definition:The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic retention of transcription factor;   cytoplasmic sequestration of transcription factor;   cytoplasmic storage of transcription factor;   maintenance of transcription factor protein location in cytoplasm;   retention of transcription factor in cytoplasm;   sequestering of transcription factor in cytoplasm;   sequestration of transcription factor in cytoplasm;   storage of transcription factor in cytoplasm;   transcription factor binding, cytoplasmic sequestering



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cytoplasmic sequestering of transcription factor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB3 cAMP responsive element binding protein 3 involved_in ISO (PMID:20091349) UniProt PMID:20091349 NCBI chr 1:236,450,573...236,456,381
Ensembl chr 1:236,450,342...236,456,373
JBrowse link
G KEAP1 kelch like ECH associated protein 1 involved_in IBA
ISO
(PMID:21873635) GO_Central
GO_Central
RGD
PMID:11439354 PMID:21873635 RGD:727319 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,297,835
JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in ISS
IEA
AgBase
AgBase
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:39,849,579...39,899,455
Ensembl chr 3:39,849,609...39,899,455
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:131,002,973...131,058,932
Ensembl chr 8:131,005,407...131,058,932
JBrowse link
G SRI sorcin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:68,492,235...68,515,247
Ensembl chr 9:68,493,008...68,515,322
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3608582|PMID:16316410)
GO_Central
Ensembl
GO_Central
MGI
PMID:16316410 PMID:21873635 GO_REF:0000107 MGI:3608582 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,614,517
JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 acts_upstream_of_or_within ISO (MGI:1926513|PMID:11025203) MGI PMID:11025203 MGI:1926513 NCBI chr 8:825,433...835,425
Ensembl chr 8:824,999...837,322
JBrowse link
G THRA thyroid hormone receptor alpha acts_upstream_of_or_within ISO (MGI:3619869|PMID:16322094) MGI PMID:16322094 MGI:3619869 NCBI chr12:22,270,506...22,296,684
Ensembl chr12:22,270,062...22,296,618
JBrowse link
cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCDC22 coiled-coil domain containing 22 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:43,285,232...43,303,865
Ensembl chr  X:43,285,246...43,307,204
JBrowse link
G FAF1 Fas associated factor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:161,173,915...161,603,731
Ensembl chr 6:161,166,996...161,603,725
JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:9343439 PMID:9918814 PMID:10620707 PMID:16580131 GO_REF:0000107 RGD:2298880 RGD:2298882 RGD:2298908 RGD:2298917 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G NFKBIB NFKB inhibitor beta involved_in IBA
ISO
(PMID:21873635) GO_Central
GO_Central
RGD
PMID:9343439 PMID:16580131 PMID:21873635 RGD:2298908 RGD:2298917 NCBI chr 6:47,703,644...47,712,661
Ensembl chr 6:47,703,636...47,712,664
JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:88,540,261...88,548,593
Ensembl chr  X:88,540,376...88,548,560
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in ISO (PMID:21343177) CAFA PMID:21343177 NCBI chr  X:9,649,516...9,651,662
Ensembl chr  X:9,650,179...9,651,661
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16975
    biological regulation 12437
      regulation of molecular function 2880
        regulation of DNA-binding transcription factor activity 438
          negative regulation of DNA-binding transcription factor activity 174
            cytoplasmic sequestering of transcription factor 14
              cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 16975
    metabolic process 10639
      cellular metabolic process 9655
        cellular aromatic compound metabolic process 5211
          nucleobase-containing compound metabolic process 5009
            nucleic acid metabolic process 4591
              RNA metabolic process 4096
                RNA biosynthetic process 3221
                  nucleic acid-templated transcription 3205
                    transcription, DNA-templated 3203
                      regulation of transcription, DNA-templated 3104
                        regulation of DNA-binding transcription factor activity 438
                          negative regulation of DNA-binding transcription factor activity 174
                            cytoplasmic sequestering of transcription factor 14
                              cytoplasmic sequestering of NF-kappaB 6
paths to the root