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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasmic sequestering of transcription factor
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Accession:GO:0042994 term browser browse the term
Definition:The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
Synonyms:exact_synonym: cytoplasmic retention of transcription factor;   cytoplasmic sequestration of transcription factor;   cytoplasmic storage of transcription factor;   maintenance of transcription factor protein location in cytoplasm;   retention of transcription factor in cytoplasm;   sequestering of transcription factor in cytoplasm;   sequestration of transcription factor in cytoplasm;   storage of transcription factor in cytoplasm;   transcription factor binding, cytoplasmic sequestering



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cytoplasmic sequestering of transcription factor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:20091349) RGD PMID:20091349 NCBI chr 5:57,817,835...57,823,171
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:11439354 PMID:21873635 RGD:727319, RGD:13792537 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:1493333) RGD PMID:1493333 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (MGI:5315699|PMID:16311606) RGD PMID:16311606 MGI:5315699 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16311606) RGD PMID:16311606 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Sri sorcin involved_in ISO (MGI:5487506|PMID:22338092) RGD PMID:22338092 MGI:5487506 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:95727|MGI:95728 (MGI:3608582|PMID:16316410)
RGD PMID:16316410 PMID:21873635 MGI:3608582, RGD:13792537 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 acts_upstream_of_or_within ISO (MGI:1926513|PMID:11025203) RGD PMID:11025203 MGI:1926513 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
JBrowse link
G Thra thyroid hormone receptor alpha acts_upstream_of_or_within ISO (MGI:3619869|PMID:16322094) RGD PMID:16322094 MGI:3619869 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc22 coiled-coil domain containing 22 involved_in ISO (PMID:23563313) RGD PMID:23563313 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244
JBrowse link
G Faf1 Fas associated factor 1 involved_in ISO
ISS
IEA
(PMID:14600157)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:14600157 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in IMP
ISO
(PMID:16938301) RGD PMID:16938301 PMID:9918814 PMID:16580131 PMID:10620707 PMID:9343439 RGD:2298880, RGD:2298917, RGD:2298882, RGD:2298908 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:9343439 PMID:21873635 PMID:16580131 RGD:2298908, RGD:13792537, RGD:2298917 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS
(PMID:18040287)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18040287 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:104,656,809...104,665,126 JBrowse link
G Tmsb4x thymosin beta 4, X-linked involved_in ISO (PMID:21343177) RGD PMID:21343177 NCBI chr  X:27,144,677...27,146,667
Ensembl chr  X:27,128,610...27,146,667
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of molecular function 3095
        negative regulation of molecular function 1184
          negative regulation of DNA-binding transcription factor activity 178
            cytoplasmic sequestering of transcription factor 14
              cytoplasmic sequestering of NF-kappaB 6
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        cellular aromatic compound metabolic process 5635
          nucleobase-containing compound metabolic process 5410
            nucleic acid metabolic process 4926
              RNA metabolic process 4397
                RNA biosynthetic process 3408
                  nucleic acid-templated transcription 3391
                    transcription, DNA-templated 3389
                      regulation of transcription, DNA-templated 3275
                        regulation of DNA-binding transcription factor activity 445
                          negative regulation of DNA-binding transcription factor activity 178
                            cytoplasmic sequestering of transcription factor 14
                              cytoplasmic sequestering of NF-kappaB 6
paths to the root