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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleolar large rRNA transcription by RNA polymerase I
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Accession:GO:0042790 term browser browse the term
Definition:The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.
Synonyms:exact_synonym: transcription of nuclear large rRNA transcript from RNA polymerase I promoter;   transcription of nuclear rRNA large Pol I transcript;   transcription of nucleolar large rRNA by RNA polymerase I


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nucleolar large rRNA transcription by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLR1E RNA polymerase I subunit E involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:53,793,324...53,808,725
Ensembl chr11:53,793,042...53,808,724 		JBrowse link
G TAF1B TATA-box binding protein associated factor, RNA polymerase I subunit B involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:6,873,275...6,940,432
Ensembl chr17:6,873,360...6,937,789 		JBrowse link
G TCOF1 treacle ribosome biogenesis factor 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:15249688) MGI
GO_Central		 PMID:15249688 GO_REF:0000033 NCBI chr 4:58,699,069...58,738,677
Ensembl chr 4:58,699,069...58,738,681 		JBrowse link
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DEDD death effector domain containing acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr38:21,341,101...21,351,665
Ensembl chr38:21,342,534...21,351,972 		JBrowse link
G MACROH2A1 macroH2A.1 histone involved_in IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr11:23,369,957...23,448,235
Ensembl chr11:23,370,300...23,438,219 		JBrowse link
G MACROH2A2 macroH2A.2 histone involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:21,057,935...21,087,097
Ensembl chr 4:21,057,947...21,086,730 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495 		JBrowse link
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:26089203) UniProt PMID:26089203 NCBI chr27:42,067,845...42,102,699
Ensembl chr27:42,067,898...42,105,870 		JBrowse link
G IPPK inositol-pentakisphosphate 2-kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,760,104...98,800,891
Ensembl chr 1:98,759,976...98,800,833 		JBrowse link
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,588,503...1,606,752
Ensembl chr10:1,588,875...1,606,750 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
G NCL nucleolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:43,330,524...43,384,909
Ensembl chr25:43,330,799...43,384,258 		JBrowse link
G NOL11 nucleolar protein 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:12,817,669...12,845,632
Ensembl chr 9:12,818,714...12,846,484 		JBrowse link
G PIH1D1 PIH1 domain containing 1 involved_in ISO (PMID:24036451)
(PMID:22368283)		 UniProt PMID:22368283 PMID:24036451 NCBI chr 1:107,045,466...107,051,281
Ensembl chr 1:107,045,697...107,051,236 		JBrowse link
G PWP1 PWP1 homolog, endonuclein involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:31,121,411...31,146,791
Ensembl chr10:31,117,044...31,146,726 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,175,489...50,268,865
Ensembl chr20:50,175,687...50,268,836 		JBrowse link
G SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:28,692,610...28,728,778
Ensembl chr26:28,692,899...28,728,783 		JBrowse link
regulation of transcription of nucleolar large rRNA by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT7 sirtuin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:377,141...383,355
Ensembl chr 9:376,445...442,919 		JBrowse link
transcription elongation by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125 		JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO (PMID:23562818) MGI PMID:23562818 NCBI chr19:23,310,911...23,344,083
Ensembl chr19:23,310,986...23,337,683 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr28:1,358,383...1,432,276
Ensembl chr28:1,361,107...1,427,162 		JBrowse link
G GTF2H5 general transcription factor IIH subunit 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:47,669,196...47,681,370
Ensembl chr 1:47,669,248...47,681,368 		JBrowse link
G POLR1E RNA polymerase I subunit E involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:53,793,324...53,808,725
Ensembl chr11:53,793,042...53,808,724 		JBrowse link
G POLR1F RNA polymerase I subunit F involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:33,845,768...33,865,686
Ensembl chr14:33,845,995...33,865,720 		JBrowse link
G POLR2E RNA polymerase II, I and III subunit E involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:57,649,836...57,653,661
Ensembl chr20:57,649,868...57,654,199 		JBrowse link
G UBTF upstream binding transcription factor acts_upstream_of_or_within ISO (PMID:23562818) MGI PMID:23562818 NCBI chr 9:19,177,778...19,189,805
Ensembl chr 9:19,179,174...19,189,181 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      metabolic process 15401
        biosynthetic process 12137
          macromolecule biosynthetic process 11172
            gene expression 10747
              DNA-templated transcription 3314
                transcription by RNA polymerase I 62
                  nucleolar large rRNA transcription by RNA polymerase I 25
                    negative regulation of transcription of nucleolar large rRNA by RNA polymerase I 4
                    positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 10
                    regulation of transcription of nucleolar large rRNA by RNA polymerase I + 15
                    transcription elongation by RNA polymerase I + 8
Path 2
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      metabolic process 15401
        primary metabolic process 13974
          nucleobase-containing compound metabolic process 9600
            nucleobase-containing compound biosynthetic process 8558
              nucleic acid biosynthetic process 8266
                RNA biosynthetic process 8163
                  DNA-templated transcription 3314
                    rRNA transcription 37
                      nucleolar large rRNA transcription by RNA polymerase I 25
                        negative regulation of transcription of nucleolar large rRNA by RNA polymerase I 4
                        positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 10
                        regulation of transcription of nucleolar large rRNA by RNA polymerase I + 15
                        transcription elongation by RNA polymerase I + 8
paths to the root