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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleolar large rRNA transcription by RNA polymerase I
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Accession:GO:0042790 term browser browse the term
Definition:The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.
Synonyms:exact_synonym: transcription of nuclear large rRNA transcript from RNA polymerase I promoter;   transcription of nuclear rRNA large Pol I transcript;   transcription of nucleolar large rRNA by RNA polymerase I


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nucleolar large rRNA transcription by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLR1E RNA polymerase I subunit E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:37,331,149...37,348,652
Ensembl chr 9:38,255,067...38,272,498 		JBrowse link
G TAF1B TATA-box binding protein associated factor, RNA polymerase I subunit B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:9,834,385...9,927,129
Ensembl chr2A:9,996,146...10,087,740 		JBrowse link
G TCOF1 treacle ribosome biogenesis factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15249688) MGI
TreeGrafter		 PMID:15249688 GO_REF:0000118 NCBI chr 5:145,781,915...145,824,312
Ensembl chr 5:151,786,944...151,825,549 		JBrowse link
negative regulation of transcription of nucleolar large rRNA by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DEDD death effector domain containing acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:136,533,756...136,545,107
Ensembl chr 1:140,447,011...140,457,876 		JBrowse link
G LOC100974647 core histone macro-H2A.2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:66,526,013...66,585,568
Ensembl chr10:69,077,456...69,114,194 		JBrowse link
G LOC100974858 core histone macro-H2A.1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,727,065...130,791,932
Ensembl chr 5:136,868,521...136,933,834 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27729611) UniProt PMID:27729611 NCBI chr19:44,739,739...44,751,303 JBrowse link
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX11 DEAD/H-box helicase 11 involved_in ISO (PMID:26089203) UniProt PMID:26089203 NCBI chr12:55,176,165...55,207,123 JBrowse link
G IPPK inositol-pentakisphosphate 2-kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:63,737,324...63,793,348
Ensembl chr 9:91,808,757...91,864,773 		JBrowse link
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,410,231...31,438,015
Ensembl chr12:31,668,708...31,693,839 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841 		JBrowse link
G NCL nucleolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:118,703,148...118,712,893
Ensembl chr2B:237,490,378...237,500,193 		JBrowse link
G NOL11 nucleolar protein 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:61,650,662...61,676,657
Ensembl chr17:66,849,998...66,875,775 		JBrowse link
G PIH1D1 PIH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,459,855...46,465,882
Ensembl chr19:55,381,803...55,387,664 		JBrowse link
G PWP1 PWP1 homolog, endonuclein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:105,255,755...105,282,519
Ensembl chr12:108,652,024...108,679,503 		JBrowse link
G SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952 		JBrowse link
G SMARCB1 SWI/SNF related BAF chromatin remodeling complex subunit B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:4,542,764...4,589,461
Ensembl chr22:22,627,982...22,673,921 		JBrowse link
regulation of transcription of nucleolar large rRNA by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT7 sirtuin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:76,317,560...76,323,761
Ensembl chr17:82,020,077...82,026,289 		JBrowse link
transcription elongation by RNA polymerase I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819 		JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO (PMID:23562818) MGI PMID:23562818 NCBI chr2B:32,983,492...33,020,492
Ensembl chr2B:127,922,483...127,959,372 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:44,703,720...44,784,948 JBrowse link
G GTF2H5 general transcription factor IIH subunit 5 acts_upstream_of_or_within ISO (PMID:23562818) MGI PMID:23562818 Ensembl chr 6:158,126,665...158,153,663 JBrowse link
G LOC103786072 DNA-directed RNA polymerases I and III subunit RPAC2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:8,910,717...8,913,420
Ensembl chr13:27,256,567...27,373,830 		JBrowse link
G POLR1F RNA polymerase I subunit F involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:20,369,819...20,383,414
Ensembl chr 7:19,692,639...19,703,338 		JBrowse link
G POLR2E RNA polymerase II, I and III subunit E involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:32,263...41,992
Ensembl chr19:1,065,421...1,073,379 		JBrowse link
G UBTF upstream binding transcription factor acts_upstream_of_or_within ISO (PMID:23562818) MGI PMID:23562818 NCBI chr17:13,176,228...13,191,283
Ensembl chr17:13,343,349...13,356,836 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18871
      metabolic process 12800
        biosynthetic process 9705
          macromolecule biosynthetic process 8781
            gene expression 8371
              DNA-templated transcription 3281
                transcription by RNA polymerase I 61
                  nucleolar large rRNA transcription by RNA polymerase I 26
                    negative regulation of transcription of nucleolar large rRNA by RNA polymerase I 4
                    positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 10
                    regulation of transcription of nucleolar large rRNA by RNA polymerase I + 15
                    transcription elongation by RNA polymerase I + 8
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18871
      metabolic process 12800
        primary metabolic process 11201
          nucleobase-containing compound metabolic process 7087
            nucleobase-containing compound biosynthetic process 6202
              nucleic acid biosynthetic process 5954
                RNA biosynthetic process 5850
                  DNA-templated transcription 3281
                    rRNA transcription 38
                      nucleolar large rRNA transcription by RNA polymerase I 26
                        negative regulation of transcription of nucleolar large rRNA by RNA polymerase I 4
                        positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 10
                        regulation of transcription of nucleolar large rRNA by RNA polymerase I + 15
                        transcription elongation by RNA polymerase I + 8
paths to the root