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ONTOLOGY REPORT - ANNOTATIONS

Term:very long-chain fatty acid biosynthetic process
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Accession:GO:0042761 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:exact_synonym: very-long-chain fatty acid anabolism;   very-long-chain fatty acid biosynthesis;   very-long-chain fatty acid formation;   very-long-chain fatty acid synthesis
 xref: MetaCyc:PWY-5080


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very long-chain fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO
IBA		 (PMID:20166112), (PMID:20937905)
GO_REF:0000033		 RGD
GO_Central		 PMID:20166112 PMID:20937905 GO_REF:0000033 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 involved_in ISO
IEA
IBA		 (PMID:12371743), (PMID:20937905)
(MGI:4939101|PMID:21106902), (MGI:4943668|PMID:12371743)
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:12371743 PMID:20937905 PMID:21106902 GO_REF:0000033 GO_REF:0000104 MGI:4939101 MGI:4943668 NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in ISO
IBA		 (PMID:20937905)
(MGI:3033509|PMID:14581464)
GO_REF:0000033		 RGD
GO_Central		 PMID:14581464 PMID:20937905 GO_REF:0000033 MGI:3033509 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in ISO
IBA		 (PMID:20937905)
GO_REF:0000033		 RGD
GO_Central		 PMID:20937905 GO_REF:0000033 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IDA
ISO
IEA
IBA		 PMID:12005057
(PMID:20427700), (PMID:20937905)
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:20427700 PMID:20937905 PMID:12005057 GO_REF:0000033 GO_REF:0000104, RGD:8554529 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in ISO
IEA
IBA		 (PMID:19826053), (PMID:20937905)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19826053 PMID:20937905 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Fads2 fatty acid desaturase 2 TAS RGD PMID:11988075 RGD:70542 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 involved_in ISO
IBA		 (PMID:18554506)
GO_REF:0000033		 RGD
GO_Central		 PMID:18554506 GO_REF:0000033 NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073 		JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 involved_in ISO
IBA		 (PMID:18554506)
GO_REF:0000033		 RGD
GO_Central		 PMID:18554506 GO_REF:0000033 NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 involved_in ISO
IBA		 (PMID:18554506)
GO_REF:0000033		 RGD
GO_Central		 PMID:18554506 GO_REF:0000033 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 involved_in ISO
IBA		 (PMID:18554506)
GO_REF:0000033		 RGD
GO_Central		 PMID:18554506 GO_REF:0000033 NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase involved_in ISO
ISS
IEA
IBA		 (PMID:12482854), (PMID:24220030)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:12482854 PMID:24220030 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Tecrl trans-2,3-enoyl-CoA reductase-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:24,732,241...24,805,272
Ensembl chr14:24,732,241...24,805,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      biosynthetic process 8418
        lipid biosynthetic process 734
          fatty acid biosynthetic process 168
            very long-chain fatty acid biosynthetic process 14
Path 2
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      cellular metabolic process 10293
        organic acid metabolic process 1033
          oxoacid metabolic process 1022
            carboxylic acid metabolic process 1007
              monocarboxylic acid metabolic process 730
                fatty acid metabolic process 454
                  very long-chain fatty acid metabolic process 34
                    very long-chain fatty acid biosynthetic process 14
paths to the root