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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of circadian rhythm
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Accession:GO:0042754 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
Synonyms:exact_synonym: down regulation of circadian rhythm;   downregulation of circadian rhythm
 narrow_synonym: inhibition of circadian rhythm


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negative regulation of circadian rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cipc CLOCK-interacting pacemaker involved_in ISO (MGI:5532917|PMID:17310242) RGD PMID:17310242 MGI:5532917 NCBI chr 6:106,595,011...106,613,732
Ensembl chr 6:106,595,105...106,613,723 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4410413|PMID:19605937), (MGI:5532917|PMID:17310242)		 UniProt
RGD		 PMID:17310242 PMID:19605937 GO_REF:0000024 MGI:4410413 MGI:5532917 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4410413|PMID:19605937)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19605937 GO_REF:0000024 GO_REF:0000107 MGI:4410413 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965 		JBrowse link
G Pasd1 PAS domain containing repressor 1 involved_in ISO (PMID:25936801) RGD PMID:25936801 NCBI chr  X:149,617,933...149,639,214
Ensembl chr  X:149,620,972...149,638,675 		JBrowse link
G Per2 period circadian regulator 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4410413|PMID:19605937)		 UniProt
RGD		 PMID:19605937 GO_REF:0000024 MGI:4410413 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 involved_in ISO (PMID:28903391)
(MGI:6285118|PMID:28903391)		 RGD PMID:28903391 MGI:6285118 NCBI chr15:45,431,402...45,498,034
Ensembl chr15:45,431,703...45,497,702 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (MGI:5014424|PMID:21680841) RGD PMID:21680841 MGI:5014424 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (MGI:5014424|PMID:21680841) RGD PMID:21680841 MGI:5014424 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase involved_in ISO (MGI:5569417|PMID:24413057) RGD PMID:24413057 MGI:5569417 NCBI chr  X:14,421,028...14,434,216
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 involved_in ISO (MGI:5569417|PMID:24413057) RGD PMID:24413057 MGI:5569417 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Suv39h2 SUV39H2 histone lysine methyltransferase involved_in ISO (MGI:5569417|PMID:24413057) RGD PMID:24413057 MGI:5569417 NCBI chr17:74,756,290...74,775,332
Ensembl chr17:74,756,306...74,775,332 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:19066225 RGD:5128864 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19491711 RGD:2317916 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA RGD PMID:18466985 RGD:6480669 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:12944496 RGD:1581422 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12944496 RGD:1581422 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
negative regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
negative regulation of locomotor rhythm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:16982424 RGD:10412019 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    negative regulation of biological process 5826
      negative regulation of circadian rhythm 20
        negative regulation of circadian sleep/wake cycle, sleep + 7
        negative regulation of circadian sleep/wake cycle, wakefulness 1
        negative regulation of locomotor rhythm 1
Path 2
Term Annotations click to browse term
  biological_process 19898
    biological regulation 13573
      regulation of biological process 13161
        regulation of circadian rhythm 139
          negative regulation of circadian rhythm 20
            negative regulation of circadian sleep/wake cycle, sleep + 7
            negative regulation of circadian sleep/wake cycle, wakefulness 1
            negative regulation of locomotor rhythm 1
paths to the root