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ONTOLOGY REPORT - ANNOTATIONS


Term:circadian sleep/wake cycle
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Accession:GO:0042745 term browser browse the term
Definition:The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.



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circadian sleep/wake cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase ISO RGD PMID:8330191 RGD:1598901 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767
JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (MGI:6503588|PMID:32889171) MGI PMID:32889171 MGI:6503588 NCBI chr16:2,239,953...4,208,718
Ensembl chr16:2,243,918...4,208,416
JBrowse link
G NLGN3 neuroligin 3 ISO RGD PMID:28958035 RGD:126790492 NCBI chr  X:55,510,729...55,532,396
Ensembl chr  X:55,513,626...55,531,371
JBrowse link
G NPAS2 neuronal PAS domain protein 2 acts_upstream_of_or_within ISO (MGI:2667759|PMID:12843397) MGI PMID:12843397 MGI:2667759 NCBI chr10:41,846,766...42,005,058
Ensembl chr10:41,847,625...42,005,469
JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:20980612 RGD:5128829 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
circadian sleep/wake cycle process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCRTR2 hypocretin receptor 2 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr12:22,517,482...22,623,358
Ensembl chr12:22,517,482...22,623,358
JBrowse link
circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTBD9 BTB domain containing 9 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5436392|PMID:22678064) MGI
Ensembl
PMID:22678064 GO_REF:0000107 MGI:5436392 NCBI chr12:7,154,805...7,564,050
Ensembl chr12:7,154,925...7,564,017
JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:17537840 RGD:2289986 NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712
JBrowse link
circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 acts_upstream_of_or_within ISO (MGI:2445919|PMID:12419540) MGI PMID:12419540 MGI:2445919 NCBI chr 3:33,878,948...34,101,987
Ensembl chr 3:33,878,904...34,097,764
JBrowse link
G LOC607874 cystatin-C-like ISO RGD PMID:17027151 RGD:2306498 NCBI chr23:49,562...53,618 JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:20844122 RGD:13515123 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669
JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO deprivation RGD PMID:12597996 RGD:4891963 NCBI chr34:7,118,814...7,144,828
Ensembl chr34:7,118,814...7,144,828
JBrowse link
G STAR steroidogenic acute regulatory protein ISO deprivation RGD PMID:12597996 RGD:4891963 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025
JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:19066225 RGD:5128864 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:19491711 RGD:2317916 NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051
JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:18466985 RGD:6480669 NCBI chr28:5,438,872...5,524,385
Ensembl chr28:5,440,388...5,524,191
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358
JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051
JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12944496 RGD:1581422 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:12944496 RGD:1581422 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
negative regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 6:74,932,789...74,986,573 JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin ISO RGD PMID:9748091 RGD:1625449 NCBI chr13:62,133,747...62,169,349
Ensembl chr13:62,053,814...62,294,709
JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:19889861 PMID:20237285 RGD:10401262 RGD:2325188 NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712
JBrowse link
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:20237285 RGD:10401262 NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753
JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510
JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:19429170 PMID:22171046 RGD:9588660 RGD:9588665 NCBI chr21:7,639,532...7,643,534
Ensembl chr21:7,640,317...7,641,498
JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO RGD PMID:16378653 RGD:1642507 NCBI chr15:52,790,136...52,797,785
Ensembl chr15:52,794,671...52,795,818
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358
JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRH growth hormone releasing hormone NOT|involved_in ISO (PMID:15538933) BHF-UCL PMID:15538933 NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712
JBrowse link
G PMCH pro-melanin concentrating hormone ISO RGD PMID:12964948 RGD:1642489 NCBI chr15:41,036,428...41,037,571
Ensembl chr15:41,036,428...41,037,553
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 5:61,503,268...61,508,146 JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598
JBrowse link
G OPN4 opsin 4 acts_upstream_of_or_within ISO (MGI:5925970|PMID:26320947) MGI PMID:26320947 MGI:5925970 NCBI chr 4:34,350,058...34,365,410
Ensembl chr 4:34,355,128...34,365,215
JBrowse link
positive regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLGN1 neuroligin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177
JBrowse link
G NPS neuropeptide S ISO RGD PMID:22300983 RGD:9831203 NCBI chr28:36,488,430...36,492,524
Ensembl chr28:36,488,500...36,492,090
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 5:61,503,268...61,508,146 JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844
regulation of circadian sleep/wake cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:22,461,556...22,469,243
Ensembl chr 9:22,461,705...22,469,053
JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722
JBrowse link
G IL6 interleukin 6 ISO RGD PMID:12667648 RGD:1358315 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:41,405,453...41,415,727
Ensembl chr 6:41,407,070...41,408,823
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (MGI:6874638|PMID:34798058) UniProt PMID:34798058 MGI:6874638 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722
JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:11038259 RGD:631747 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G ADRB1 adrenoceptor beta 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr28:24,908,224...24,909,684
Ensembl chr28:24,908,224...24,909,684
JBrowse link
G CSF2 colony stimulating factor 2 ISO RGD PMID:12047622 RGD:10449529 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:15913875 RGD:1625069 NCBI chr33:18,369,362...18,414,465
Ensembl chr33:18,372,865...18,412,277
JBrowse link
G LOC611347 uncharacterized LOC611347 involved_in ISO PMID:20233222 UniProt PMID:20233222 RGD:12911001 NCBI chr13:47,865,037...48,047,697
Ensembl chr13:47,865,002...47,893,921
JBrowse link
G PER3 period circadian regulator 3 involved_in ISO (PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630)
(MGI:5300112|PMID:21957163)
UniProt PMID:17346965 PMID:19716732 PMID:21957163 PMID:24439663 PMID:24577121 More... MGI:5300112 NCBI chr 5:61,445,580...61,499,393
Ensembl chr 5:61,445,461...61,498,499
JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 ISO RGD PMID:11145837 RGD:724610 NCBI chr 1:109,614,404...109,618,242
Ensembl chr 1:109,614,437...109,618,242
JBrowse link
G PTGDS prostaglandin D2 synthase involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 9:48,647,334...48,650,608
Ensembl chr 9:48,646,255...48,669,814
JBrowse link
regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCRTR2 hypocretin receptor 2 involved_in IMP (PMID:11282968) UniProt
UniProt
PMID:11282968 NCBI chr12:22,517,482...22,623,358
Ensembl chr12:22,517,482...22,623,358
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17343
    rhythmic process 403
      circadian rhythm 272
        circadian behavior 69
          circadian sleep/wake cycle 44
            circadian sleep/wake cycle process + 38
            regulation of circadian sleep/wake cycle + 33
Path 2
Term Annotations click to browse term
  biological_process 17343
    multicellular organismal process 7902
      behavior 803
        rhythmic behavior 72
          circadian behavior 69
            circadian sleep/wake cycle 44
              circadian sleep/wake cycle process + 38
              regulation of circadian sleep/wake cycle + 33
paths to the root