Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:hydrogen peroxide metabolic process
go back to main search page
Accession:GO:0042743 term browser browse the term
Definition:The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms:exact_synonym: H2O2 metabolic process;   hydrogen peroxide metabolism



show annotations for term's descendants           Sort by:
hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOXA1 dual oxidase maturation factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23770197) Ensembl
MGI
PMID:23770197 GO_REF:0000107 NCBI chr15:24,064,967...24,077,641
Ensembl chr15:42,418,234...42,430,749
JBrowse link
G DUOXA2 dual oxidase maturation factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23770197) Ensembl
MGI
PMID:23770197 GO_REF:0000107 NCBI chr15:24,061,922...24,066,016
Ensembl chr15:42,415,195...42,418,974
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:21258655 RGD:5131481 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G LOC100986481 cytochrome c acts_upstream_of_or_within ISO (PMID:16757556) MGI PMID:16757556 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549
JBrowse link
G NOX1 NADPH oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:90,046,023...90,076,968
Ensembl chr  X:100,182,398...100,215,192
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17766438) Ensembl
MGI
PMID:17766438 GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271
JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:15259009), (PMID:17325201) MGI PMID:15259009 PMID:17325201 NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369
JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:16716903 RGD:1580833 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
cellular detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G TXN thioredoxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:81,399,056...81,411,607
Ensembl chr 9:109,565,557...109,578,311
JBrowse link
detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271
JBrowse link
hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:69,890,817...69,928,342
Ensembl chr17:75,445,923...75,479,571
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14980704) Ensembl
MGI
PMID:14980704 GO_REF:0000107 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14980704) Ensembl
MGI
PMID:14980704 GO_REF:0000107 NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447
JBrowse link
G DUOX1 dual oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:24,077,557...24,113,206
Ensembl chr15:42,431,595...42,467,943
JBrowse link
G DUOX2 dual oxidase 2 involved_in ISO (PMID:16651268), (PMID:19339556), (PMID:22814254), (PMID:25761904) UniProt PMID:16651268 PMID:19339556 PMID:22814254 PMID:25761904 NCBI chr15:24,040,513...24,061,758
Ensembl chr15:42,395,135...42,414,281
JBrowse link
G LOC100982531 cytochrome b-245 heavy chain acts_upstream_of_or_within ISO (PMID:15258578) MGI PMID:15258578 NCBI chr  X:30,230,394...30,267,379
Ensembl chr  X:37,939,704...37,973,183
JBrowse link
G LOC100986914 cytochrome b-245 light chain involved_in ISO PMID:8798532 BHF-UCL PMID:8798532 RGD:2317869 NCBI chr16:69,356,396...69,364,225
Ensembl chr16:89,016,349...89,024,719
JBrowse link
G NCF1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (PMID:15258578) MGI PMID:15258578 Ensembl chr 7:81,917,167...81,932,589 JBrowse link
G SOD1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in
ISO (PMID:14679182)
(PMID:15544046)
RGD
MGI
UniProt
PMID:10640619 PMID:12514262 PMID:14679182 PMID:15544046 PMID:15880490 RGD:1581090 RGD:1601266 RGD:634854 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15642720 RGD:2291946 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382
JBrowse link
G CAT catalase involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:10617683), (PMID:17275685), (PMID:9600348)
(PMID:642030)
(PMID:15178682)
RGD
TreeGrafter
MGI
InterPro
UniProt
Ensembl
PMID:642030 PMID:9600348 PMID:10617683 PMID:14713308 PMID:15178682 More... GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:1358492 RGD:2292202 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G DUOX1 dual oxidase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr15:24,077,557...24,113,206
Ensembl chr15:42,431,595...42,467,943
JBrowse link
G DUOX2 dual oxidase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr15:24,040,513...24,061,758
Ensembl chr15:42,395,135...42,414,281
JBrowse link
G GPX1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10754271)
(PMID:10915565), (PMID:11545230), (PMID:15182862), (PMID:9788901)
(PMID:15827346)
Ensembl
TreeGrafter
MGI
PMID:9788901 PMID:10754271 PMID:10915565 PMID:11545230 PMID:15182862 More... GO_REF:0000107 GO_REF:0000118 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826
JBrowse link
G GPX3 glutathione peroxidase 3 acts_upstream_of_or_within ISO (PMID:10617683) MGI PMID:10617683 NCBI chr 5:146,447,939...146,456,476 JBrowse link
G HBA1 hemoglobin subunit alpha 1 involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 Ensembl chr16:164,618...165,476 JBrowse link
G HBE1 hemoglobin subunit epsilon 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:5,417,347...5,419,147
Ensembl chr11:5,085,677...5,087,483
JBrowse link
G HBM hemoglobin subunit mu involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr16:157,767...158,559 JBrowse link
G HBQ1 hemoglobin subunit theta 1 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr16:170,684...171,524 JBrowse link
G LOC100970029 peroxiredoxin-2-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:11,574,364...11,575,820 JBrowse link
G LOC100976465 hemoglobin subunit beta involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr11:5,374,486...5,376,111
Ensembl chr11:5,043,095...5,044,826
JBrowse link
G LOC100977135 hemoglobin subunit delta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:5,381,854...5,383,637
Ensembl chr11:5,050,308...5,052,243
JBrowse link
G LOC100982657 hemoglobin subunit gamma-1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:5,397,268...5,399,048 JBrowse link
G LOC100984160 hemoglobin subunit alpha involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 Ensembl chr16:164,724...167,873 JBrowse link
G LOC100987590 glutathione peroxidase 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:5,986,126...5,987,229 JBrowse link
G LOC117978663 hemoglobin subunit zeta involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr16:153,991...155,872 JBrowse link
G MPO myeloperoxidase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11907569)
(PMID:10085024)
MGI
Ensembl
PMID:10085024 PMID:11907569 GO_REF:0000107 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G PRDX1 peroxiredoxin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11986303) MGI
TreeGrafter
Ensembl
PMID:11986303 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:44,813,508...44,824,430
Ensembl chr 1:46,171,453...46,182,018
JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15902258) MGI
TreeGrafter
PMID:15902258 GO_REF:0000118 NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369
JBrowse link
G PRDX3 peroxiredoxin 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:7733872) MGI
TreeGrafter
Ensembl
PMID:7733872 GO_REF:0000107 GO_REF:0000118 NCBI chr10:115,738,346...115,749,482
Ensembl chr10:119,162,714...119,173,845
JBrowse link
G PRDX4 peroxiredoxin 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:16,266,501...16,285,458
Ensembl chr  X:23,641,701...23,660,267
JBrowse link
G PRDX5 peroxiredoxin 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:59,675,138...59,678,804
Ensembl chr11:63,020,097...63,023,624
JBrowse link
G PRDX6 peroxiredoxin 6 ISO RGD PMID:8641418 RGD:729495 NCBI chr 1:148,988,836...149,000,345 JBrowse link
G PXDN peroxidasin involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:1,584,901...1,699,675
Ensembl chr2A:1,582,193...1,692,033
JBrowse link
G TPO thyroid peroxidase involved_in IEA UniProt GO_REF:0000043 NCBI chr2A:1,364,083...1,491,284
Ensembl chr2A:1,335,556...1,493,055
JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO RGD PMID:10849437 RGD:634378 NCBI chr12:101,862,703...101,925,104
Ensembl chr12:105,187,128...105,321,112
JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter ISO RGD PMID:26482480 RGD:12910938 NCBI chr17:3,686,903...3,711,857
Ensembl chr17:3,683,575...3,708,253
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISO PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451
JBrowse link
G LOC100986481 cytochrome c ISO RGD PMID:21410437 RGD:7349317 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549
JBrowse link
G MPV17L MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) BHF-UCL PMID:22306510
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100972567 haptoglobin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:52,907,739...52,912,781
Ensembl chr16:71,901,278...71,905,998
JBrowse link
G LOC103782687 haptoglobin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:52,942,214...52,947,034
Ensembl chr16:71,901,278...71,905,998
JBrowse link
G LOC103783441 haptoglobin-related protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:52,926,044...52,940,038
Ensembl chr16:71,901,278...71,905,998
JBrowse link
G MT3 metallothionein 3 ISO RGD PMID:12058024 RGD:625483 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093
JBrowse link
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 involved_in ISO (PMID:18606987) BHF-UCL PMID:18606987 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642
JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOXA1 dual oxidase maturation factor 1 involved_in ISO (PMID:22814254) UniProt PMID:22814254 NCBI chr15:24,064,967...24,077,641
Ensembl chr15:42,418,234...42,430,749
JBrowse link
G DUOXA2 dual oxidase maturation factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:24,061,922...24,066,016
Ensembl chr15:42,415,195...42,418,974
JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077
JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:27279484 RGD:151347625 NCBI chr11:84,330,362...84,496,755 JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G ZNF205 zinc finger protein 205 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,054,056...2,061,992
Ensembl chr16:3,233,794...3,241,216
JBrowse link
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NNT nicotinamide nucleotide transhydrogenase ISO RGD PMID:24722990 RGD:13513981 NCBI chr 5:66,662,249...66,772,352
Ensembl chr 5:71,719,257...71,823,242
JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600
JBrowse link
regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSR insulin receptor ISO in cerebellar granule neurons RGD PMID:17919343 RGD:2290474 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G NOXA1 NADPH oxidase activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,490,455...108,503,555
Ensembl chr 9:137,455,874...137,468,196
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:17325201) MGI PMID:17325201 NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19444
    cellular process 18997
      metabolic process 12930
        reactive oxygen species metabolic process 268
          hydrogen peroxide metabolic process 60
            detoxification of hydrogen peroxide + 3
            hydrogen peroxide biosynthetic process + 21
            hydrogen peroxide catabolic process + 33
            negative regulation of hydrogen peroxide metabolic process + 11
            positive regulation of hydrogen peroxide metabolic process + 8
            regulation of hydrogen peroxide metabolic process + 23
paths to the root