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ONTOLOGY REPORT - ANNOTATIONS


Term:fibrinolysis
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Accession:GO:0042730 term browser browse the term
Definition:A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
Synonyms:xref: Wikipedia:Fibrinolysis


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fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3027337|PMID:14702107) Ensembl
MGI
PMID:14702107 GO_REF:0000107 MGI:3027337 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G CPB2 carboxypeptidase B2 involved_in IBA
ISO
IEA
(PMID:21873635) GO_Central
RGD
InterPro
PMID:11848438 PMID:21873635 GO_REF:0000002 RGD:632532 NCBI chr13:46,053,066...46,105,033
Ensembl chr13:46,053,186...46,105,033
JBrowse link
G F12 coagulation factor XII involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:177,402,138...177,409,564
Ensembl chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,141...177,409,564
JBrowse link
G F2 coagulation factor II, thrombin involved_in IDA (PMID:12855810) UniProt PMID:12855810 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FGA fibrinogen alpha chain involved_in IDA
IBA
(PMID:16846481)
(PMID:21873635)
UniProt
GO_Central
PMID:16846481 PMID:21873635 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FGB fibrinogen beta chain involved_in IDA (PMID:16846481) UniProt PMID:16846481 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGG fibrinogen gamma chain involved_in IDA (PMID:16846481) UniProt PMID:16846481 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha involved_in IDA (PMID:12855810) UniProt PMID:12855810 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023
JBrowse link
G HRG histidine rich glycoprotein involved_in TAS Reactome Reactome:R-HSA-75205 NCBI chr 3:186,665,975...186,678,235
Ensembl chr 3:186,660,216...186,678,234
Ensembl chr 3:186,660,216...186,678,234
JBrowse link
G KLKB1 kallikrein B1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:186,215,714...186,258,477
Ensembl chr 4:186,208,979...186,258,471
JBrowse link
G KRT1 keratin 1 involved_in NAS (PMID:11290596) UniProt PMID:11290596 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
JBrowse link
G PLAT plasminogen activator, tissue type involved_in TAS Reactome Reactome:R-HSA-75205 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,676
Ensembl chr 8:42,174,718...42,207,676
JBrowse link
G PLAU plasminogen activator, urokinase involved_in
acts_upstream_of_or_within
TAS
ISO
IBA
(MGI:1277054|PMID:9733098)
(PMID:21873635)
Reactome
MGI
GO_Central
PMID:9733098 PMID:21873635 MGI:1277054 Reactome:R-HSA-75205 NCBI chr10:73,909,182...73,917,497
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in TAS Reactome Reactome:R-HSA-75205 NCBI chr19:43,646,095...43,670,197
Ensembl chr19:43,646,095...43,670,547
JBrowse link
G PLG plasminogen involved_in TAS
IDA
(PMID:14688145), (PMID:17307854), (PMID:22025510) Reactome
CAFA
PMID:14688145 PMID:17307854 PMID:22025510 Reactome:R-HSA-75205 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G PROS1 protein S involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:93,873,051...93,973,896
Ensembl chr 3:93,873,051...93,980,003
Ensembl chr 3:93,873,051...93,980,003
JBrowse link
G SERPINB2 serpin family B member 2 involved_in TAS Reactome Reactome:R-HSA-75205 NCBI chr18:63,887,705...63,903,890
Ensembl chr18:63,871,692...63,903,888
JBrowse link
G SERPINE1 serpin family E member 1 involved_in TAS Reactome Reactome:R-HSA-75205 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SERPINF2 serpin family F member 2 involved_in TAS Reactome Reactome:R-HSA-75205 NCBI chr17:1,742,808...1,755,265
Ensembl chr17:1,742,836...1,755,265
Ensembl chr17:1,742,836...1,755,265
JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,614,848
Ensembl chr11:57,597,387...57,614,848
Ensembl chr11:57,597,387...57,614,848
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IDA (PMID:14726399) BHF-UCL PMID:14726399 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
JBrowse link
G CPB2 carboxypeptidase B2 involved_in IEA
ISO
Ensembl
RGD
PMID:17002650 GO_REF:0000107 RGD:2313647 NCBI chr13:46,053,066...46,105,033
Ensembl chr13:46,053,186...46,105,033
JBrowse link
G F2 coagulation factor II, thrombin involved_in TAS (PMID:17379830) BHF-UCL PMID:17379830 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G HRG histidine rich glycoprotein involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3789419|PMID:15869579)
GO_Central
MGI
PMID:15869579 PMID:21873635 MGI:3789419 NCBI chr 3:186,665,975...186,678,235
Ensembl chr 3:186,660,216...186,678,234
Ensembl chr 3:186,660,216...186,678,234
JBrowse link
G PLG plasminogen involved_in IDA (PMID:14726399) BHF-UCL PMID:14726399 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
G SERPINE1 serpin family E member 1 involved_in IDA (PMID:2503541) BHF-UCL PMID:2503541 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SERPINF2 serpin family F member 2 involved_in IDA
IEA
ISO
(PMID:134998) BHF-UCL
Ensembl
RGD
PMID:134998 PMID:6506034 GO_REF:0000107 RGD:1625541 NCBI chr17:1,742,808...1,755,265
Ensembl chr17:1,742,836...1,755,265
Ensembl chr17:1,742,836...1,755,265
JBrowse link
G THBD thrombomodulin involved_in TAS (PMID:17379830) BHF-UCL PMID:17379830 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G THBS1 thrombospondin 1 involved_in IDA (PMID:6438154) BHF-UCL PMID:6438154 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G USF1 upstream transcription factor 1 involved_in IC (PMID:18234320) BHF-UCL PMID:18234320 NCBI chr 1:161,039,251...161,045,977
Ensembl chr 1:161,039,251...161,045,977
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in IDA (PMID:89876) BHF-UCL PMID:89876 NCBI chr 4:186,265,964...186,290,727
Ensembl chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681
JBrowse link
G F12 coagulation factor XII involved_in IDA (PMID:89876) BHF-UCL PMID:89876 NCBI chr 5:177,402,138...177,409,564
Ensembl chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,141...177,409,564
JBrowse link
G KLKB1 kallikrein B1 involved_in IDA (PMID:89876) BHF-UCL PMID:89876 NCBI chr 4:186,215,714...186,258,477
Ensembl chr 4:186,208,979...186,258,471
JBrowse link
G PLG plasminogen involved_in IDA (PMID:26667841), (PMID:6438154) BHF-UCL PMID:6438154 PMID:26667841 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,238...160,754,097
Ensembl chr 6:160,702,238...160,754,097
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IDA (PMID:16480936) BHF-UCL PMID:16480936 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
JBrowse link
G FAP fibroblast activation protein alpha involved_in IC (PMID:17317851) BHF-UCL PMID:17317851 NCBI chr 2:162,170,684...162,243,472
Ensembl chr 2:162,170,684...162,245,151
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18673
    negative regulation of biological process 6262
      negative regulation of hemostasis 60
        negative regulation of blood coagulation 59
          fibrinolysis 26
            negative regulation of fibrinolysis 10
            positive regulation of fibrinolysis 4
            regulation of fibrinolysis + 14
Path 2
Term Annotations click to browse term
  biological_process 18673
    biological regulation 13349
      regulation of biological process 12687
        regulation of response to stimulus 4644
          regulation of response to stress 1710
            regulation of response to wounding 187
              regulation of wound healing 143
                regulation of blood coagulation 76
                  negative regulation of blood coagulation 59
                    fibrinolysis 26
                      negative regulation of fibrinolysis 10
                      positive regulation of fibrinolysis 4
                      regulation of fibrinolysis + 14
paths to the root