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ONTOLOGY REPORT - ANNOTATIONS


Term:muscle cell fate commitment
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Accession:GO:0042693 term browser browse the term
Definition:The process in which the cellular identity of muscle cells is acquired and determined.



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muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:3629660 (MGI:3578606|PMID:15800000) RGD PMID:15800000 MGI:3578606 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2179190 (MGI:3809316|PMID:18816853)
UniProt
RGD
PMID:18816853 GO_REF:0000024 MGI:3809316 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:3040116|PMID:15109497)
Ensembl
RGD
PMID:15109497 GO_REF:0000107 MGI:3040116 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wnt8a Wnt family member 8A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr18:26,137,690...26,143,283
Ensembl chr18:26,137,690...26,143,283
JBrowse link
cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:19506109)
GO_REF:0000107
RGD
Ensembl
PMID:19506109 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:2143322 (MGI:5295932|PMID:21554246) RGD PMID:21554246 MGI:5295932 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wt1 WT1 transcription factor involved_in ISO (MGI:5285454|PMID:21654746) RGD PMID:21654746 MGI:5285454 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
muscle cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:3718323 (MGI:3763703|PMID:17786239) RGD PMID:17786239 MGI:3763703 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Tbx2 T-box transcription factor 2 acts_upstream_of_or_within ISO MGI:3505715 (MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:3487212 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
muscle cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO (MGI:67939|PMID:1379240) RGD PMID:1379240 MGI:67939 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (MGI:5432296|PMID:22711842) RGD PMID:22711842 MGI:5432296 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular developmental process 4543
        cell fate commitment 282
          muscle cell fate commitment 15
            cardiac muscle cell fate commitment + 10
            muscle cell fate determination + 2
            muscle cell fate specification + 1
            vascular associated smooth muscle cell fate commitment + 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular developmental process 4543
        cell differentiation 4448
          muscle cell differentiation 439
            muscle cell fate commitment 15
              cardiac muscle cell fate commitment + 10
              muscle cell fate determination + 2
              muscle cell fate specification + 1
              vascular associated smooth muscle cell fate commitment + 0
paths to the root