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ONTOLOGY REPORT - ANNOTATIONS
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Term:
auditory receptor cell fate specification
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Accession:
GO:0042667
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Definition:
The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Synonyms:
exact_synonym:
auditory hair cell fate specification
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Rat (2)
Mouse (2)
Human (2)
Chinchilla (2)
Bonobo (2)
Dog (2)
Squirrel (2)
Pig (2)
Green Monkey (2)
Naked Mole-rat (2)
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Genes (2)
auditory receptor cell fate specification
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Atoh1
atonal bHLH transcription factor 1
acts_upstream_of_or_within
IMP
(PMID:10364557)
MGI
PMID:10364557
NCBI chr 6:64,706,109...64,708,229
Ensembl chr 6:64,706,109...64,708,229
regulation of inner ear auditory receptor cell fate specification
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Esrp1
epithelial splicing regulatory protein 1
involved_in
IMP
(PMID:29107558)
UniProt
PMID:29107558
NCBI chr 4:11,331,933...11,386,783
Ensembl chr 4:11,331,933...11,386,783
Term paths to the root
one shortest
all shortest
one longest
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one shortest and longest
all
Path 1
Term
Annotations
biological_process
28636
cellular process
18394
cellular developmental process
5150
cell fate specification
117
neuron fate specification
42
auditory receptor cell fate specification
2
negative regulation of auditory receptor cell fate specification
0
regulation of inner ear auditory receptor cell fate specification
+
1
Path 2
Term
Annotations
biological_process
28636
developmental process
7494
anatomical structure development
6964
multicellular organism development
5540
system development
4764
nervous system development
2923
neurogenesis
2149
generation of neurons
1841
neuron differentiation
1761
mechanoreceptor differentiation
103
inner ear receptor cell differentiation
95
inner ear auditory receptor cell differentiation
66
auditory receptor cell fate commitment
6
auditory receptor cell fate specification
2
negative regulation of auditory receptor cell fate specification
0
regulation of inner ear auditory receptor cell fate specification
+
1