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ONTOLOGY REPORT - ANNOTATIONS

Term:retinoic acid metabolic process
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Accession:GO:0042573 term browser browse the term
Definition:The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
Synonyms:exact_synonym: retinoic acid metabolism;   vitamin A1 acid metabolic process;   vitamin A1 acid metabolism

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retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10358022), (PMID:10402668) Ensembl
MGI
TreeGrafter		 PMID:10358022 PMID:10402668 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936520:3,467,003...3,489,754
Ensembl chrNW_004936520:3,467,003...3,490,997 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family member A1 acts_upstream_of_or_within ISO (PMID:10191271)
(PMID:16207763)
(PMID:12808103), (PMID:12851412)		 MGI PMID:10191271 PMID:12808103 PMID:12851412 PMID:16207763 NCBI chrNW_004936503:8,869,073...8,953,726
Ensembl chrNW_004936503:8,868,961...8,918,532 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16368932)
(PMID:8797830)
(PMID:14623241)		 RGD
MGI
Ensembl		 PMID:8797830 PMID:12547725 PMID:14623241 PMID:16368932 GO_REF:0000107 RGD:1576367 NCBI chrNW_004936471:19,175,997...19,263,335
Ensembl chrNW_004936471:19,175,992...19,263,335 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16207763)
(PMID:17207476)		 Ensembl
MGI		 PMID:16207763 PMID:17207476 GO_REF:0000107 NCBI chrNW_004936483:2,930,781...2,967,309
Ensembl chrNW_004936483:2,930,789...2,967,346 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936560:2,562,394...2,580,261
Ensembl chrNW_004936560:2,562,748...2,580,201 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9826179) Ensembl
MGI		 PMID:9826179 GO_REF:0000107 NCBI chrNW_004936580:5,861,051...5,866,818
Ensembl chrNW_004936580:5,860,562...5,866,856 		JBrowse link
G LOC101965278 retinol dehydrogenase 16 ISO RGD PMID:7499345 RGD:1299624 NCBI chrNW_004936646:1,195,200...1,200,778
Ensembl chrNW_004936646:1,194,547...1,200,897 		JBrowse link
G LOC101967606 cytochrome P450 2S1-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936661:3,642,674...3,652,697
Ensembl chrNW_004936661:3,642,707...3,651,774 		JBrowse link
G LOC101970102 cytochrome P450 27C1 involved_in ISO (PMID:27059013) UniProt PMID:27059013 NCBI chrNW_004936469:44,016,925...44,042,569 JBrowse link
G LOC101975674 cytochrome P450 26B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:16,010,394...16,028,852
Ensembl chrNW_004936491:16,010,070...16,028,895 		JBrowse link
G LOC101976546 alcohol dehydrogenase E chain involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936520:3,508,821...3,552,938 JBrowse link
G LOC101976827 alcohol dehydrogenase 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936520:3,651,829...3,677,841 JBrowse link
G LOC101977861 cytochrome P450 26A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15531370) Ensembl
MGI		 PMID:15531370 GO_REF:0000107 NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074 		JBrowse link
G Rbp1 retinol binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15193143) Ensembl
MGI		 PMID:15193143 GO_REF:0000107 NCBI chrNW_004936540:1,600,673...1,626,573
Ensembl chrNW_004936540:1,600,398...1,626,652 		JBrowse link
G Scpep1 serine carboxypeptidase 1 ISO RGD PMID:11447226 RGD:70518 NCBI chrNW_004936490:5,903,884...5,939,953
Ensembl chrNW_004936490:5,904,396...5,939,915 		JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family member A1 acts_upstream_of_or_within ISO (PMID:11876656) MGI PMID:11876656 NCBI chrNW_004936503:8,869,073...8,953,726
Ensembl chrNW_004936503:8,868,961...8,918,532 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11876656) Ensembl
MGI		 PMID:11876656 GO_REF:0000107 NCBI chrNW_004936471:19,175,997...19,263,335
Ensembl chrNW_004936471:19,175,992...19,263,335 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11876656) Ensembl
MGI		 PMID:11876656 GO_REF:0000107 NCBI chrNW_004936560:2,562,394...2,580,261
Ensembl chrNW_004936560:2,562,748...2,580,201 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:10,465,701...10,487,534
Ensembl chrNW_004936469:10,465,701...10,487,534 		JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD PMID:8765131 RGD:2306683 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332 		JBrowse link
9-cis-retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family member A1 ISO RGD PMID:17167544 RGD:2306320 NCBI chrNW_004936503:8,869,073...8,953,726
Ensembl chrNW_004936503:8,868,961...8,918,532 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936654:1,336,546...1,464,959
Ensembl chrNW_004936654:1,336,429...1,461,476 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101965278 retinol dehydrogenase 16 ISO RGD PMID:21138835 RGD:6771354 NCBI chrNW_004936646:1,195,200...1,200,778
Ensembl chrNW_004936646:1,194,547...1,200,897 		JBrowse link
G Rdh10 retinol dehydrogenase 10 ISO RGD PMID:21138835 RGD:6771354 NCBI chrNW_004936648:2,060,131...2,088,021
Ensembl chrNW_004936648:2,060,125...2,088,833 		JBrowse link
retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family member A1 ISO RGD PMID:21138835 RGD:6771354 NCBI chrNW_004936503:8,869,073...8,953,726
Ensembl chrNW_004936503:8,868,961...8,918,532 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15950969 PMID:21138835 GO_REF:0000107 RGD:6771322 RGD:6771354 NCBI chrNW_004936471:19,175,997...19,263,335
Ensembl chrNW_004936471:19,175,992...19,263,335 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11013254), (PMID:11044606), (PMID:16241904) RGD
MGI
Ensembl		 PMID:11013254 PMID:11044606 PMID:15950969 PMID:16241904 PMID:21138835 GO_REF:0000107 RGD:6771322 RGD:6771354 NCBI chrNW_004936483:2,930,781...2,967,309
Ensembl chrNW_004936483:2,930,789...2,967,346 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004936580:5,861,051...5,866,818
Ensembl chrNW_004936580:5,860,562...5,866,856 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 ISO RGD PMID:15950969 PMID:21138835 RGD:6771322 RGD:6771354 NCBI chrNW_004936469:10,465,701...10,487,534
Ensembl chrNW_004936469:10,465,701...10,487,534 		JBrowse link
G Rbp1 retinol binding protein 1 involved_in ISO
IEA		 RGD
InterPro		 PMID:15950969 GO_REF:0000002 RGD:6771322 NCBI chrNW_004936540:1,600,673...1,626,573
Ensembl chrNW_004936540:1,600,398...1,626,652 		JBrowse link
G Rdh10 retinol dehydrogenase 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17473173) Ensembl
MGI		 PMID:17473173 GO_REF:0000107 NCBI chrNW_004936648:2,060,131...2,088,021
Ensembl chrNW_004936648:2,060,125...2,088,833 		JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101970215 cytochrome P450 2W1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:1,203,004...1,208,131
Ensembl chrNW_004936754:1,203,017...1,208,131 		JBrowse link
G LOC101975674 cytochrome P450 26B1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21138835 GO_REF:0000107 RGD:6771354 NCBI chrNW_004936491:16,010,394...16,028,852
Ensembl chrNW_004936491:16,010,070...16,028,895 		JBrowse link
G LOC101977861 cytochrome P450 26A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074 		JBrowse link
G LOC101978131 cytochrome P450 26C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:1,818,037...1,828,400
Ensembl chrNW_004936601:1,817,983...1,828,185 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    metabolic process 9527
      hormone metabolic process 209
        retinoic acid metabolic process 21
          9-cis-retinoic acid metabolic process + 5
          retinoic acid biosynthetic process + 11
          retinoic acid catabolic process 4
          retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
Path 2
Term Annotations click to browse term
  biological_process 15871
    metabolic process 9527
      primary metabolic process 8310
        lipid metabolic process 1279
          cellular lipid metabolic process 957
            isoprenoid metabolic process 101
              terpenoid metabolic process 73
                diterpenoid metabolic process 63
                  retinoid metabolic process 55
                    retinoic acid metabolic process 21
                      9-cis-retinoic acid metabolic process + 5
                      retinoic acid biosynthetic process + 11
                      retinoic acid catabolic process 4
                      retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
paths to the root