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ONTOLOGY REPORT - ANNOTATIONS

Term:retinoic acid metabolic process
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Accession:GO:0042573 term browser browse the term
Definition:The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
Synonyms:exact_synonym: retinoic acid metabolism;   vitamin A1 acid metabolic process;   vitamin A1 acid metabolism

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retinoic acid metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1 (class I) ISO
IBA		 MGI:2180099|MGI:2180100|MGI:97876 (MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412), (MGI:3510590|PMID:15193143)
PMID:21873635		 RGD PMID:10358022 PMID:12851412 PMID:15193143, PMID:21873635 MGI:1338643 MGI:2675573 MGI:3510590, RGD:13792537 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:243,656,568...243,687,857
Ensembl chr 2:243,550,627...243,687,857 		JBrowse link
G Adh6a alcohol dehydrogenase 6A (class V) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:243,577,086...243,599,357
Ensembl chr 2:243,577,082...243,599,400 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
MGI:2180102 (MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668)		 Ensembl
RGD		 PMID:10358022 PMID:10402668, PMID:21873635 GO_REF:0000107 MGI:1338643 MGI:1340177, RGD:13792537 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISO MGI:1861722|MGI:2667220|MGI:3609477 (MGI:1336449|PMID:10191271), (MGI:2664447|PMID:12808103), (MGI:2675573|PMID:12851412), (MGI:3608158|PMID:16207763) RGD PMID:10191271 PMID:12808103 PMID:12851412 PMID:16207763 MGI:1336449 MGI:2664447 MGI:2675573 MGI:3608158 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 TAS
ISO
IDA		 MGI:1857891|MGI:2180721 (MGI:2681052|PMID:14623241), (MGI:3612223|PMID:16368932), (MGI:83148|PMID:8797830) RGD PMID:8797830 PMID:14623241 PMID:16368932, PMID:15205379, PMID:12547725 MGI:2681052 MGI:3612223 MGI:83148, RGD:1576366, RGD:1576367 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 ISO (PMID:11585737)
MGI:1353450|MGI:3043947|MGI:3512079 (MGI:3608158|PMID:16207763), (MGI:3701419|PMID:17207476)		 RGD PMID:11585737 PMID:16207763 PMID:17207476 MGI:3608158 MGI:3701419 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 ISO (PMID:11007799) RGD PMID:11007799 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 NAS
ISO		 (MGI:1313226|PMID:9826179) RGD PMID:9826179, PMID:7750498 MGI:1313226, RGD:61557 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 ISO (PMID:22020119), (PMID:9716180)
MGI:2183292 (MGI:1195386|PMID:9442090), (MGI:3522528|PMID:15531370), (MGI:894533|PMID:9250660)		 RGD PMID:9250660 PMID:9442090 PMID:9716180 PMID:15531370 PMID:22020119 MGI:1195386 MGI:3522528 MGI:894533 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 ISS
ISO		 GO_REF:0000024
(PMID:22020119)		 UniProt
RGD		 PMID:22020119 GO_REF:0000024 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 ISO (PMID:11093772) RGD PMID:11093772 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 ISO (PMID:11093772) RGD PMID:11093772 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 ISO (PMID:12711469) RGD PMID:12711469 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 ISO (PMID:11093772) RGD PMID:11093772 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 ISO (PMID:11093772) RGD PMID:11093772 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 NAS RGD PMID:12390888 RGD:633755 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325 		JBrowse link
G Rbp1 retinol binding protein 1 ISO MGI:2181412|MGI:87921 (MGI:3510590|PMID:15193143) RGD PMID:15193143 MGI:3510590 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842 		JBrowse link
G Rdh16 retinol dehydrogenase 16 IDA RGD PMID:7499345 RGD:1299624 NCBI chr 7:71,058,150...71,072,685
Ensembl chr 7:70,980,422...71,072,689 		JBrowse link
G Scpep1 serine carboxypeptidase 1 IEP RGD PMID:11447226 RGD:70518 NCBI chr10:76,230,371...76,263,866
Ensembl chr10:76,230,373...76,263,866 		JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IEA
ISO		 GO_REF:0000107
(MGI:2662611|PMID:11876656)		 Ensembl
RGD		 PMID:11876656 GO_REF:0000107 MGI:2662611 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD PMID:8765131 RGD:2306683 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 ISO
ISS		 (PMID:11304534)
GO_REF:0000024		 RGD
UniProt		 PMID:11304534 GO_REF:0000024 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325 		JBrowse link
G Rdh16 retinol dehydrogenase 16 ISO (MGI:2662611|PMID:11876656) RGD PMID:11876656 MGI:2662611 NCBI chr 7:71,058,150...71,072,685
Ensembl chr 7:70,980,422...71,072,689 		JBrowse link
9-cis-retinoic acid metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IDA RGD PMID:17167544 RGD:2306320 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 5:2,605,265...2,631,905
Ensembl chr 5:2,603,505...2,632,030 		JBrowse link
G Rdh16 retinol dehydrogenase 16 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 7:71,058,150...71,072,685
Ensembl chr 7:70,980,422...71,072,689 		JBrowse link
retinoic acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 IEP
ISO
ISS
IMP		 (PMID:29240402)
GO_REF:0000024		 RGD
UniProt		 PMID:29240402, PMID:15950969, PMID:21138835 GO_REF:0000024, RGD:6771322, RGD:6771354 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEP
ISO
ISS
IEA
IMP		 (MGI:1927016|PMID:11044606), (MGI:3042765|PMID:14623956), (MGI:3055622|PMID:11013254), (MGI:3692370|PMID:16241904)
GO_REF:0000024
(PMID:27759097)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11013254 PMID:11044606 PMID:14623956 PMID:16241904 PMID:27759097, PMID:15950969, PMID:21138835 GO_REF:0000024 GO_REF:0000107 MGI:1927016 MGI:3042765 MGI:3055622 MGI:3692370, RGD:6771322, RGD:6771354 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 IEP RGD PMID:15950969 RGD:6771322 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 IEP
IDA		 RGD PMID:15950969, PMID:21138835 RGD:6771322, RGD:6771354 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325 		JBrowse link
G Rbp1 retinol binding protein 1 IEP RGD PMID:15950969 RGD:6771322 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842 		JBrowse link
G Rdh10 retinol dehydrogenase 10 ISO (MGI:3709664|PMID:17473173) RGD PMID:17473173 MGI:3709664 NCBI chr 5:2,605,265...2,631,905
Ensembl chr 5:2,603,505...2,632,030 		JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crabp1 cellular retinoic acid binding protein 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:59,344,097...59,352,135
Ensembl chr 8:59,344,083...59,352,132 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 ISO (PMID:10823918)
(MGI:894533|PMID:9250660)		 RGD PMID:9250660 PMID:10823918 MGI:894533 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 IMP
ISO		 (PMID:10823918) RGD PMID:10823918, PMID:21138835 RGD:6771354 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615 		JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 ISO (PMID:14532297) RGD PMID:14532297 NCBI chr 1:256,369,410...256,380,649
Ensembl chr 1:256,370,850...256,378,335 		JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 ISO (PMID:26936974) RGD PMID:26936974 NCBI chr12:17,382,749...17,387,909
Ensembl chr12:17,383,159...17,387,879 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    metabolic process 12102
      cellular metabolic process 11041
        cellular hormone metabolic process 136
          retinoic acid metabolic process 26
            9-cis-retinoic acid metabolic process + 6
            retinoic acid biosynthetic process + 11
            retinoic acid catabolic process 5
            retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
Path 2
Term Annotations click to browse term
  biological_process 20045
    metabolic process 12102
      primary metabolic process 10848
        lipid metabolic process 1377
          cellular lipid metabolic process 1022
            isoprenoid metabolic process 119
              terpenoid metabolic process 94
                diterpenoid metabolic process 83
                  retinoid metabolic process 74
                    retinoic acid metabolic process 26
                      9-cis-retinoic acid metabolic process + 6
                      retinoic acid biosynthetic process + 11
                      retinoic acid catabolic process 5
                      retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
paths to the root