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ONTOLOGY REPORT - ANNOTATIONS


Term:retinoic acid metabolic process
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Accession:GO:0042573 term browser browse the term
Definition:The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
Synonyms:exact_synonym: retinoic acid metabolism;   vitamin A1 acid metabolic process;   vitamin A1 acid metabolism


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retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1 (class I) acts_upstream_of_or_within
involved_in
IMP
IBA
IGI
(MGI:3510590|PMID:15193143)
(MGI:6201960|PMID:21873635)
(MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412)
MGI
GO_Central
PMID:10358022 PMID:12851412 PMID:15193143 PMID:21873635 MGI:1338643 MGI:2675573 MGI:3510590 MGI:6201960 NCBI chr 3:138,277,585...138,290,698
Ensembl chr 3:138,260,991...138,290,698
JBrowse link
G Adh6a alcohol dehydrogenase 6A (class V) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:138,313,286...138,331,134
Ensembl chr 3:138,313,286...138,331,134
JBrowse link
G Adh6b alcohol dehydrogenase 6B (class V) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:138,341,412...138,358,859
Ensembl chr 3:138,341,775...138,358,861
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10358022 PMID:10402668 PMID:21873635 MGI:1338643 MGI:1340177 MGI:6201960 NCBI chr 3:138,198,064...138,232,042
Ensembl chr 3:138,217,760...138,233,382
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 acts_upstream_of_or_within IDA
IMP
IGI
(MGI:1336449|PMID:10191271)
(MGI:3608158|PMID:16207763)
(MGI:2664447|PMID:12808103), (MGI:2675573|PMID:12851412)
MGI PMID:10191271 PMID:12808103 PMID:12851412 PMID:16207763 MGI:1336449 MGI:2664447 MGI:2675573 MGI:3608158 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 acts_upstream_of_or_within IDA
ISO
IMP
(MGI:83148|PMID:8797830)
(MGI:3612223|PMID:16368932)
(MGI:2681052|PMID:14623241)
MGI PMID:8797830 PMID:14623241 PMID:16368932 GO_REF:0000096 MGI:2681052 MGI:3612223 MGI:4417868 MGI:83148 NCBI chr 9:71,215,789...71,296,243
Ensembl chr 9:71,215,789...71,296,243
JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 involved_in
acts_upstream_of_or_within
ISO
IMP
IGI
(PMID:11585737)
(MGI:3608158|PMID:16207763)
(MGI:3701419|PMID:17207476)
UniProt
MGI
PMID:11585737 PMID:16207763 PMID:17207476 GO_REF:0000096 MGI:3608158 MGI:3701419 MGI:4834177 NCBI chr 7:66,390,892...66,427,477
Ensembl chr 7:66,390,890...66,427,517
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 NOT|acts_upstream_of_or_within IDA (MGI:1336449|PMID:10191271) MGI PMID:10191271 MGI:1336449 NCBI chr19:20,692,953...20,727,556
Ensembl chr19:20,692,953...20,727,562
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 involved_in ISO (PMID:11007799) UniProt
MGI
PMID:11007799 GO_REF:0000096 MGI:4834177 NCBI chr10:21,377,300...21,396,578
Ensembl chr10:21,377,291...21,396,585
JBrowse link
G Bco2 beta-carotene oxygenase 2 involved_in NAS (MGI:2159483|PMID:11278918) UniProt PMID:11278918 MGI:2159483 NCBI chr 9:50,533,087...50,555,214
Ensembl chr 9:50,533,087...50,555,181
JBrowse link
G Crabp2 cellular retinoic acid binding protein II acts_upstream_of_or_within IDA (MGI:1313226|PMID:9826179) MGI PMID:9826179 MGI:1313226 NCBI chr 3:87,948,693...87,953,372
Ensembl chr 3:87,948,666...87,953,376
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within
ISO
IDA
IMP
(PMID:22020119), (PMID:9716180)
(MGI:1195386|PMID:9442090), (MGI:894533|PMID:9250660)
(MGI:3522528|PMID:15531370)
UniProt
UniProt
MGI
PMID:9250660 PMID:9442090 PMID:9716180 PMID:15531370 PMID:22020119 GO_REF:0000096 MGI:1195386 MGI:3522528 MGI:4834177 MGI:894533 NCBI chr19:37,697,738...37,701,536
Ensembl chr19:37,697,798...37,701,536
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in
acts_upstream_of_or_within
ISO
IC
(PMID:22020119)
(MGI:3037623|PMID:15030763)
UniProt
MGI
PMID:15030763 PMID:22020119 GO_REF:0000096 MGI:3037623 MGI:4834177 NCBI chr 6:84,571,414...84,593,908
Ensembl chr 6:84,571,414...84,593,908
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 involved_in ISO (PMID:11093772) UniProt PMID:11093772 NCBI chr19:39,287,044...39,330,713
Ensembl chr19:39,269,405...39,330,713
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 involved_in ISO (PMID:11093772) UniProt
MGI
PMID:11093772 GO_REF:0000096 MGI:4834177 NCBI chr19:39,006,940...39,042,690
Ensembl chr19:39,007,019...39,042,693
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in ISO (PMID:12711469) UniProt
MGI
PMID:12711469 GO_REF:0000096 MGI:4834177 NCBI chr 7:25,802,469...25,816,525
Ensembl chr 7:25,802,475...25,816,913
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 involved_in ISO (PMID:11093772) UniProt
MGI
PMID:11093772 GO_REF:0000096 MGI:4834177 NCBI chr 5:137,892,933...137,925,610
Ensembl chr 5:137,892,932...137,921,619
JBrowse link
G Cyp3a41a cytochrome P450, family 3, subfamily a, polypeptide 41A involved_in ISO (PMID:11093772) UniProt PMID:11093772 NCBI chr 5:145,694,049...145,720,136
Ensembl chr 5:145,694,049...145,720,136
JBrowse link
G Lcn5 lipocalin 5 acts_upstream_of_or_within TAS (MGI:1861869|PMID:10936050) MGI PMID:10936050 MGI:1861869 NCBI chr 2:25,657,932...25,662,230
Ensembl chr 2:25,657,952...25,661,977
JBrowse link
G Rbp1 retinol binding protein 1, cellular acts_upstream_of_or_within IGI
IMP
(MGI:3510590|PMID:15193143) MGI PMID:15193143 MGI:3510590 NCBI chr 9:98,422,961...98,446,551
Ensembl chr 9:98,422,961...98,446,575
JBrowse link
G Rdh16 retinol dehydrogenase 16 ISO RGD PMID:7499345 RGD:1299624 NCBI chr10:127,801,090...127,815,846
Ensembl chr10:127,801,152...127,846,565
JBrowse link
G Scpep1 serine carboxypeptidase 1 ISO RGD PMID:11447226 RGD:70518 NCBI chr11:88,924,020...88,955,442
Ensembl chr11:88,924,020...88,955,465
JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 acts_upstream_of_or_within IDA (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 acts_upstream_of_or_within IDA (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chr 9:71,215,789...71,296,243
Ensembl chr 9:71,215,789...71,296,243
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 acts_upstream_of_or_within IDA (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chr10:21,377,300...21,396,578
Ensembl chr10:21,377,291...21,396,585
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Dhrs9 dehydrogenase/reductase (SDR family) member 9 involved_in ISO (PMID:11304534) UniProt
MGI
PMID:11304534 GO_REF:0000096 MGI:4834177 NCBI chr 2:69,380,462...69,403,086
Ensembl chr 2:69,380,445...69,404,533
JBrowse link
G Rdh16 retinol dehydrogenase 16 acts_upstream_of_or_within IDA (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chr10:127,801,090...127,815,846
Ensembl chr10:127,801,152...127,846,565
JBrowse link
G Rdh9 retinol dehydrogenase 9 acts_upstream_of_or_within IDA (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chr10:127,776,405...127,792,697
Ensembl chr10:127,776,386...127,792,697
JBrowse link
9-cis-retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c18 aldo-keto reductase family 1, member C18 involved_in ISO (PMID:21851338) UniProt
MGI
PMID:21851338 GO_REF:0000096 MGI:4834177 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 (all-trans) acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 1:16,105,882...16,132,550
Ensembl chr 1:16,105,774...16,133,734
JBrowse link
G Rdh16 retinol dehydrogenase 16 ISO RGD PMID:21138835 RGD:6771354 NCBI chr10:127,801,090...127,815,846
Ensembl chr10:127,801,152...127,846,565
JBrowse link
retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 involved_in
acts_upstream_of_or_within
ISO (PMID:29240402) UniProt
MGI
PMID:29240402 GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 9:71,215,789...71,296,243
Ensembl chr 9:71,215,789...71,296,243
JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 involved_in
acts_upstream_of_or_within
ISO
IMP
IDA
(PMID:27759097)
(MGI:3042765|PMID:14623956)
(MGI:1927016|PMID:11044606), (MGI:3055622|PMID:11013254), (MGI:3692370|PMID:16241904)
UniProt
UniProt
MGI
PMID:11013254 PMID:11044606 PMID:14623956 PMID:16241904 PMID:27759097 GO_REF:0000096 MGI:1927016 MGI:3042765 MGI:3055622 MGI:3692370 MGI:4417868 MGI:4834177 NCBI chr 7:66,390,892...66,427,477
Ensembl chr 7:66,390,890...66,427,517
JBrowse link
G Crabp2 cellular retinoic acid binding protein II ISO RGD PMID:15950969 RGD:6771322 NCBI chr 3:87,948,693...87,953,372
Ensembl chr 3:87,948,666...87,953,376
JBrowse link
G Dhrs9 dehydrogenase/reductase (SDR family) member 9 acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:69,380,462...69,403,086
Ensembl chr 2:69,380,445...69,404,533
JBrowse link
G Rbp1 retinol binding protein 1, cellular involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 9:98,422,961...98,446,551
Ensembl chr 9:98,422,961...98,446,575
JBrowse link
G Rdh10 retinol dehydrogenase 10 (all-trans) acts_upstream_of_or_within IMP (MGI:3709664|PMID:17473173) MGI PMID:17473173 MGI:3709664 NCBI chr 1:16,105,882...16,132,550
Ensembl chr 1:16,105,774...16,133,734
JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crabp1 cellular retinoic acid binding protein I involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 9:54,764,748...54,773,110
Ensembl chr 9:54,764,748...54,773,110
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within
ISO
IDA
(PMID:10823918)
(MGI:894533|PMID:9250660)
(MGI:1350515|PMID:10588879)
BHF-UCL
MGI
PMID:9250660 PMID:10588879 PMID:10823918 GO_REF:0000096 MGI:1350515 MGI:4834177 MGI:894533 NCBI chr19:37,697,738...37,701,536
Ensembl chr19:37,697,798...37,701,536
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in
acts_upstream_of_or_within
ISO
IC
(PMID:10823918)
(MGI:5466369|PMID:22366455)
BHF-UCL
MGI
PMID:10823918 PMID:22366455 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:5466369 NCBI chr 6:84,571,414...84,593,908
Ensembl chr 6:84,571,414...84,593,908
JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily c, polypeptide 1 involved_in ISO (PMID:14532297) BHF-UCL
MGI
PMID:14532297 GO_REF:0000096 MGI:4834177 NCBI chr19:37,685,112...37,693,320
Ensembl chr19:37,685,581...37,693,398
JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 involved_in ISO (PMID:26936974) UniProt
MGI
PMID:26936974 GO_REF:0000096 MGI:4834177 NCBI chr 5:139,352,616...139,359,607
Ensembl chr 5:139,352,617...139,357,033
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23340
    metabolic process 11120
      cellular metabolic process 10066
        cellular hormone metabolic process 125
          retinoic acid metabolic process 30
            9-cis-retinoic acid metabolic process + 7
            retinoic acid biosynthetic process + 12
            retinoic acid catabolic process 5
            retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
Path 2
Term Annotations click to browse term
  biological_process 23340
    metabolic process 11120
      primary metabolic process 9804
        lipid metabolic process 1353
          cellular lipid metabolic process 989
            isoprenoid metabolic process 104
              terpenoid metabolic process 82
                diterpenoid metabolic process 73
                  retinoid metabolic process 64
                    retinoic acid metabolic process 30
                      9-cis-retinoic acid metabolic process + 7
                      retinoic acid biosynthetic process + 12
                      retinoic acid catabolic process 5
                      retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
paths to the root