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ONTOLOGY REPORT - ANNOTATIONS

Term:retinoic acid metabolic process
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Accession:GO:0042573 term browser browse the term
Definition:The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
Synonyms:exact_synonym: retinoic acid metabolism;   vitamin A1 acid metabolic process;   vitamin A1 acid metabolism

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retinoic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide acts_upstream_of_or_within ISO (MGI:3510590|PMID:15193143)
(MGI:1338643|PMID:10358022), (MGI:2675573|PMID:12851412)		 MGI PMID:10358022 PMID:12851412 PMID:15193143 MGI:1338643 MGI:2675573 MGI:3510590 NCBI chrNW_004955496:8,136,279...8,149,496 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide acts_upstream_of_or_within ISO (MGI:1338643|PMID:10358022), (MGI:1340177|PMID:10402668) MGI PMID:10358022 PMID:10402668 MGI:1338643 MGI:1340177 NCBI chrNW_004955496:8,065,943...8,100,878
Ensembl chrNW_004955496:8,065,943...8,102,066 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within ISO (MGI:2681052|PMID:14623241)
(MGI:83148|PMID:8797830)
(MGI:3612223|PMID:16368932)		 RGD
MGI		 PMID:8797830 PMID:12547725 PMID:14623241 PMID:16368932 MGI:2681052 MGI:3612223 MGI:83148 RGD:1576367 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in
acts_upstream_of_or_within		 ISO (PMID:11585737)
(MGI:3701419|PMID:17207476)
(MGI:3608158|PMID:16207763)		 UniProt
MGI		 PMID:11585737 PMID:16207763 PMID:17207476 MGI:3608158 MGI:3701419 NCBI chrNW_004955416:27,823,611...27,858,112
Ensembl chrNW_004955416:27,823,611...27,858,173 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 involved_in ISO (PMID:11007799) UniProt PMID:11007799 NCBI chrNW_004955439:1,773,884...1,794,325
Ensembl chrNW_004955439:1,773,861...1,794,328 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 acts_upstream_of_or_within ISO (MGI:1313226|PMID:9826179) MGI PMID:9826179 MGI:1313226 NCBI chrNW_004955545:2,777,523...2,782,567
Ensembl chrNW_004955545:2,777,474...2,782,567 		JBrowse link
G LOC102010839 cytochrome P450 2S1 involved_in ISO (PMID:12711469) UniProt PMID:12711469 NCBI chrNW_004955555:167,634...183,572
Ensembl chrNW_004955555:168,139...182,196 		JBrowse link
G LOC102023166 cytochrome P450 26B1 involved_in ISO (PMID:22020119) UniProt PMID:22020119 NCBI chrNW_004955424:13,336,189...13,355,368
Ensembl chrNW_004955424:13,336,189...13,355,423 		JBrowse link
G Rbp1 retinol binding protein 1 acts_upstream_of_or_within ISO (MGI:3510590|PMID:15193143) MGI PMID:15193143 MGI:3510590 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288 		JBrowse link
G Scpep1 serine carboxypeptidase 1 ISO RGD PMID:11447226 RGD:70518 NCBI chrNW_004955451:5,847,371...5,876,286
Ensembl chrNW_004955451:5,846,552...5,876,851 		JBrowse link
9-cis-retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family member A1 acts_upstream_of_or_within ISO (MGI:2662611|PMID:11876656) MGI PMID:11876656 MGI:2662611 NCBI chrNW_004955439:1,773,884...1,794,325
Ensembl chrNW_004955439:1,773,861...1,794,328 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 involved_in ISO (PMID:11304534) UniProt PMID:11304534 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267 		JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO 9-cis- and all-trans-retinoic acid synthesized from 9-cis- and all-trans-retinal RGD PMID:8765131 RGD:2306683 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in ISO (PMID:33495566) UniProt PMID:33495566 NCBI chrNW_004955476:1,222,579...1,331,582
Ensembl chrNW_004955476:1,223,076...1,331,582 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 ISO RGD PMID:21138835 RGD:6771354 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421 		JBrowse link
retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 involved_in ISO (PMID:29240402) RGD
UniProt		 PMID:15950969 PMID:21138835 PMID:29240402 RGD:6771322 RGD:6771354 NCBI chrNW_004955450:16,406,578...16,453,048
Ensembl chrNW_004955450:16,406,436...16,453,180 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in
acts_upstream_of_or_within		 ISO (MGI:3042765|PMID:14623956)
(MGI:1927016|PMID:11044606), (MGI:3055622|PMID:11013254), (MGI:3692370|PMID:16241904)
(PMID:27759097)		 RGD
UniProt
MGI		 PMID:11013254 PMID:11044606 PMID:14623956 PMID:15950969 PMID:16241904 More... MGI:1927016 MGI:3042765 MGI:3055622 MGI:3692370 RGD:6771322 RGD:6771354 NCBI chrNW_004955416:27,823,611...27,858,112
Ensembl chrNW_004955416:27,823,611...27,858,173 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004955545:2,777,523...2,782,567
Ensembl chrNW_004955545:2,777,474...2,782,567 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 ISO RGD PMID:15950969 PMID:21138835 RGD:6771322 RGD:6771354 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267 		JBrowse link
G Rbp1 retinol binding protein 1 ISO RGD PMID:15950969 RGD:6771322 NCBI chrNW_004955508:6,046,738...6,072,202
Ensembl chrNW_004955508:6,046,316...6,072,288 		JBrowse link
G Rdh10 retinol dehydrogenase 10 acts_upstream_of_or_within ISO (MGI:3709664|PMID:17473173) MGI PMID:17473173 MGI:3709664 NCBI chrNW_004955444:6,878,722...6,909,421
Ensembl chrNW_004955444:6,878,722...6,909,421 		JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102016571 cytochrome P450 2W1 involved_in ISO (PMID:26936974) UniProt PMID:26936974 NCBI chrNW_004955460:8,705,068...8,711,266
Ensembl chrNW_004955460:8,705,068...8,712,121 		JBrowse link
G LOC102023166 cytochrome P450 26B1 involved_in ISO (PMID:10823918) RGD
BHF-UCL		 PMID:10823918 PMID:21138835 RGD:6771354 NCBI chrNW_004955424:13,336,189...13,355,368
Ensembl chrNW_004955424:13,336,189...13,355,423 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12270
    metabolic process 7820
      hormone metabolic process 167
        retinoic acid metabolic process 15
          9-cis-retinoic acid metabolic process + 4
          retinoic acid biosynthetic process + 9
          retinoic acid catabolic process 2
          retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
Path 2
Term Annotations click to browse term
  biological_process 12270
    metabolic process 7820
      primary metabolic process 6969
        lipid metabolic process 979
          cellular lipid metabolic process 725
            isoprenoid metabolic process 65
              terpenoid metabolic process 50
                diterpenoid metabolic process 45
                  retinoid metabolic process 37
                    retinoic acid metabolic process 15
                      9-cis-retinoic acid metabolic process + 4
                      retinoic acid biosynthetic process + 9
                      retinoic acid catabolic process 2
                      retinoic acid metabolic process in spinal cord anterior-posterior patterning 0
paths to the root