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ONTOLOGY REPORT - ANNOTATIONS


Term:hormone binding
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Accession:GO:0042562 term browser browse the term
Definition:Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.


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hormone binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase ISO (PMID:26989199) UniProtKB PMID:26989199 NCBI chrNW_004936483:14,974,053...15,079,824 JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 ISO (PMID:14750901) UniProtKB PMID:14750901 NCBI chrNW_004936512:10,706,043...10,712,797 JBrowse link
G Calr calreticulin ISO RGD PMID:12603316 RGD:2326186 NCBI chrNW_004936659:1,994,695...1,999,070 JBrowse link
G Crym crystallin mu ISO (MGI:3703173|PMID:17264173) MGI PMID:17264173 MGI:3703173 NCBI chrNW_004936501:6,441,968...6,457,814 JBrowse link
G Esr1 estrogen receptor 1 ISO 17-beta-estradiol (E2) RGD PMID:15105439 PMID:17928626 RGD:1580331 RGD:5128669 NCBI chrNW_004936489:4,616,839...4,887,179 JBrowse link
G Esr2 estrogen receptor 2 ISO 17-beta-estradiol (E2) RGD PMID:15105439 PMID:17928626 RGD:1580331 RGD:5128669 NCBI chrNW_004936495:7,956,168...8,018,356 JBrowse link
G Ghsr growth hormone secretagogue receptor ISO PMID:10604470 UniProt PMID:10604470 RGD:625505 NCBI chrNW_004936593:268,736...273,623 JBrowse link
G Hk3 hexokinase 3 ISO RGD PMID:11068878 RGD:2302674 NCBI chrNW_004936597:1,122,648...1,143,342 JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:15131016 RGD:10053635 NCBI chrNW_004936469:10,245,001...10,438,933 JBrowse link
G Mc1r melanocortin 1 receptor ISO RGD PMID:16454799 RGD:1626221 NCBI chrNW_004936641:193,885...198,730 JBrowse link
G Mc4r melanocortin 4 receptor ISO RGD PMID:21527895 RGD:6478803 NCBI chrNW_004936497:4,636,370...4,638,205 JBrowse link
G Mc5r melanocortin 5 receptor ISO RGD PMID:8179577 PMID:16454799 RGD:1626221 RGD:729030 NCBI chrNW_004936626:3,203,437...3,204,743 JBrowse link
G Mchr1 melanin concentrating hormone receptor 1 ISO RGD PMID:12505154 RGD:628540 NCBI chrNW_004936492:1,153,895...1,156,980 JBrowse link
G Mlnr motilin receptor ISO (PMID:10381885) GO_Central PMID:10381885 NCBI chrNW_004936565:2,321,799...2,326,871 JBrowse link
G Mtnr1a melatonin receptor 1A ISO (PMID:10531408) BHF-UCL PMID:10531408 NCBI chrNW_004936554:3,013,106...3,047,171 JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO (PMID:12547834) UniProtKB PMID:12547834 NCBI chrNW_004936580:3,479,858...3,496,896 JBrowse link
G Npr2 natriuretic peptide receptor 2 ISO (PMID:1672777) UniProtKB PMID:1672777 NCBI chrNW_004936524:3,779,398...3,798,074 JBrowse link
G Npr3 natriuretic peptide receptor 3 ISO (PMID:16870210) CAFA PMID:16870210 NCBI chrNW_004936518:8,093,111...8,158,862 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:21325249 RGD:5686350 NCBI chrNW_004936504:10,960,069...11,056,834 JBrowse link
G Pgr progesterone receptor ISO RGD PMID:11113338 RGD:1601290 NCBI chrNW_004936551:6,498,553...6,573,212 JBrowse link
G Rxfp1 relaxin family peptide receptor 1 ISO (MGI:2159399|PMID:11809971) MGI PMID:11809971 MGI:2159399 NCBI chrNW_004936576:4,996,203...5,131,485 JBrowse link
G Serpina7 serpin family A member 7 ISO RGD PMID:1520259 RGD:1600135 NCBI chrNW_004936499:8,568,309...8,573,764 JBrowse link
G Ttr transthyretin ISO RGD PMID:11995998 RGD:737655 NCBI chrNW_004936682:1,628,489...1,635,495 JBrowse link
G Ucn2 urocortin 2 ISO (PMID:11329063) UniProtKB PMID:11329063 NCBI chrNW_004936529:347,411...348,040 JBrowse link
adiponectin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 ISO (PMID:12802337)
(MGI:3043961|PMID:12802337)
UniProtKB
MGI
PMID:12802337 MGI:3043961 NCBI chrNW_004936567:1,658,405...1,674,794 JBrowse link
G Adipor2 adiponectin receptor 2 ISO (PMID:12802337)
(MGI:3043961|PMID:12802337)
UniProtKB
MGI
PMID:12802337 MGI:3043961 NCBI chrNW_004936606:1,911,104...2,007,109 JBrowse link
G Cdh13 cadherin 13 ISO (MGI:3055457|PMID:15210937) BHF-UCL PMID:15210937 MGI:3055457 NCBI chrNW_004936641:3,925,185...4,223,421 JBrowse link
adrenomedullin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcrl calcitonin receptor like receptor ISO (PMID:20074556), (PMID:22102369) UniProtKB PMID:20074556 PMID:22102369 NCBI chrNW_004936506:10,191,789...10,292,355 JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO (PMID:22102369) UniProtKB PMID:22102369 NCBI chrNW_004936490:17,479,899...17,481,788 JBrowse link
androgen binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO (PMID:12799378), (PMID:25091737), (PMID:3353726) UniProt
RGD
PMID:2341409 PMID:3353726 PMID:12799378 PMID:25091737 RGD:1298681 NCBI chrNW_004936635:485,903...647,820 JBrowse link
G Tspo translocator protein ISO RGD PMID:8918981 RGD:2317178 NCBI chrNW_004936718:992,301...995,172 JBrowse link
calcitonin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor NOT ISO (PMID:15563840)
(PMID:8078488)
(PMID:7588285)
(PMID:7769107), (PMID:8078488)
UniProtKB
RGD
PMID:7588285 PMID:7723741 PMID:7769107 PMID:8078488 PMID:15563840 RGD:2303052 NCBI chrNW_004936803:423,558...466,762 JBrowse link
calcitonin gene-related peptide binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ramp1 receptor activity modifying protein 1 ISO (PMID:9620797) UniProtKB PMID:9620797 NCBI chrNW_004936525:503,119...540,159 JBrowse link
choriogonadotropin hormone binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO (MGI:5318037|PMID:10493819) BHF-UCL PMID:10493819 MGI:5318037 NCBI chrNW_004936508:3,928,467...3,983,481 JBrowse link
corticotropin-releasing hormone binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhbp corticotropin releasing hormone binding protein ISO (MGI:74926|PMID:7556876)
(MGI:5315362|PMID:12895416)
(PMID:18234674)
(PMID:1846945)
RGD
MGI
UniProt
UniProtKB
PMID:1846945 PMID:7556876 PMID:11572971 PMID:12895416 PMID:18234674 MGI:5315362 MGI:74926 RGD:5508795 RGD:69816 NCBI chrNW_004936549:64,866...78,272 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:12942143 RGD:1358326 NCBI chrNW_004936541:2,288,847...2,333,129 JBrowse link
epidermal growth factor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO (MGI:52273|PMID:7678348) RGD
MGI
PMID:7678348 PMID:15486316 MGI:52273 RGD:1581908 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Sec61b SEC61 translocon subunit beta ISO (PMID:19602593) UniProtKB PMID:19602593 NCBI chrNW_004936524:7,731,033...7,739,410 JBrowse link
G Shc1 SHC adaptor protein 1 ISO (MGI:3057041|PMID:15467833) UniProt PMID:15467833 MGI:3057041 NCBI chrNW_004936580:4,511,560...4,522,003 JBrowse link
insulin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd2l C2CD2 like ISO (MGI:5522601|PMID:24012759) MGI PMID:24012759 MGI:5522601 NCBI chrNW_004936542:4,058,945...4,068,187 JBrowse link
G Ide insulin degrading enzyme ISO (PMID:17051221)
(PMID:20082125)
UniProtKB
RGD
PMID:15749695 PMID:17051221 PMID:20082125 RGD:1626704 NCBI chrNW_004936601:2,230,477...2,318,562 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO (PMID:8452530) BHF-UCL PMID:8452530 NCBI chrNW_004936483:4,563,995...4,860,231 JBrowse link
G Insr insulin receptor ISO (PMID:8440175)
(PMID:8452530)
associated with streptozocin;protein:altered activity:liver (rat)
UniProtKB
BHF-UCL
RGD
PMID:2180315 PMID:3275643 PMID:8440175 PMID:8452530 PMID:12850498 PMID:17023527 RGD:14981592 RGD:1580595 RGD:1600765 RGD:2293184 NCBI chrNW_004936588:4,345,306...4,453,380 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO (PMID:8440175) UniProtKB PMID:8440175 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
peptide hormone binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 ISO RGD PMID:1386737 RGD:7241860 NCBI chrNW_004936662:926,302...959,964 JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:12942143 RGD:1358326 NCBI chrNW_004936545:1,788,995...1,795,842 JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:7624319 PMID:19047484 RGD:2312649 RGD:61542 NCBI chrNW_004936557:6,415,544...6,423,863 JBrowse link
G Cckar cholecystokinin A receptor ISO (PMID:8503909) GO_Central PMID:8503909 NCBI chrNW_004936477:3,306,898...3,314,659 JBrowse link
G Cckbr cholecystokinin B receptor ISO (PMID:7681836) GO_Central PMID:7681836 NCBI chrNW_004936842:329,551...341,491 JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19334530 RGD:5130955 NCBI chrNW_004936478:6,901,098...6,947,719 JBrowse link
G Ednrb endothelin receptor type B ISO (PMID:1713452) BHF-UCL PMID:1713452 NCBI chrNW_004936511:3,446,864...3,478,434 JBrowse link
G Fshr follicle stimulating hormone receptor ISO RGD PMID:16899567 RGD:4140424 NCBI chrNW_004936508:3,601,205...3,754,234 JBrowse link
G Galr1 galanin receptor 1 ISO (PMID:24517231) UniProtKB PMID:24517231 NCBI chrNW_004936616:2,007,339...2,020,737 JBrowse link
G Galr2 galanin receptor 2 ISO (PMID:24517231)
(PMID:9832121)
UniProtKB
GO_Central
PMID:9832121 PMID:24517231 NCBI chrNW_004936594:1,236,281...1,239,213 JBrowse link
G Galr3 galanin receptor 3 ISO (PMID:24517231)
(PMID:9832121)
UniProtKB
GO_Central
PMID:9832121 PMID:24517231 NCBI chrNW_004936492:3,301,409...3,303,512 JBrowse link
G Gcgr glucagon receptor ISO RGD PMID:8552628 PMID:15687107 PMID:17010343 RGD:1625210 RGD:2315004 RGD:2315020 NCBI chrNW_004936594:5,347,789...5,351,852 JBrowse link
G Ghr growth hormone receptor ISO (PMID:1549776), (PMID:2825030), (PMID:8943276), (PMID:9571026)
(MGI:1347647|PMID:10556780)
BHF-UCL
MGI
PMID:1549776 PMID:2825030 PMID:8943276 PMID:9571026 PMID:10556780 MGI:1347647 NCBI chrNW_004936518:235,996...380,225 JBrowse link
G Ghrhr growth hormone releasing hormone receptor ISO (PMID:7680413)
(MGI:3833824|PMID:11773624)
BHF-UCL PMID:7680413 PMID:11773624 MGI:3833824 NCBI chrNW_004936478:7,188,826...7,202,854 JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:17109695 RGD:1624382 NCBI chrNW_004936593:268,736...273,623 JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO RGD PMID:8958204 RGD:2312537 NCBI chrNW_004936706:2,052,069...2,062,722 JBrowse link
G Glp1r glucagon like peptide 1 receptor ISO RGD PMID:1326760 RGD:727535 NCBI chrNW_004936476:20,541,812...20,580,454 JBrowse link
G Hcrtr1 hypocretin receptor 1 ISO RGD PMID:12890892 RGD:1642020 NCBI chrNW_004936474:14,735,654...14,744,112 JBrowse link
G Hcrtr2 hypocretin receptor 2 ISO RGD PMID:12890892 RGD:1642020 NCBI chrNW_004936476:5,838,663...5,933,174 JBrowse link
G Ide insulin degrading enzyme ISO RGD PMID:15494400 RGD:1626705 NCBI chrNW_004936601:2,230,477...2,318,562 JBrowse link
G Inhba inhibin subunit beta A ISO (PMID:16198295) UniProtKB PMID:16198295 NCBI chrNW_004936478:16,878,725...16,884,065 JBrowse link
G Lepr leptin receptor ISO RGD PMID:9070213 PMID:17023527 RGD:1600765 RGD:2290293 NCBI chrNW_004936591:5,771,371...5,846,177 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO human chorionic gonadotropin
binding is to the hCG alpha subunit; beta subunit included in complex via interaction with alpha
RGD PMID:1714448 PMID:2601325 PMID:2925659 PMID:3782111 PMID:15901736 RGD:2292553 RGD:2292578 RGD:2292580 RGD:2292582 RGD:2292594 NCBI chrNW_004936508:3,928,467...3,983,481 JBrowse link
G Mc3r melanocortin 3 receptor ISO RGD PMID:17023527 RGD:1600765 NCBI chrNW_004936875:172,764...174,446 JBrowse link
G Mc4r melanocortin 4 receptor ISO RGD PMID:17023527 RGD:1600765 NCBI chrNW_004936497:4,636,370...4,638,205 JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO (PMID:1660465) UniProtKB PMID:1660465 NCBI chrNW_004936580:3,479,858...3,496,896 JBrowse link
G Npr2 natriuretic peptide receptor 2 ISO (PMID:1660465), (PMID:26980729) RGD
UniProtKB
PMID:1660465 PMID:16537417 PMID:26980729 RGD:1601488 NCBI chrNW_004936524:3,779,398...3,798,074 JBrowse link
G Npr3 natriuretic peptide receptor 3 ISO PMID:9843699
(PMID:1660465)
BHF-UCL
UniProtKB
RGD
PMID:1660465 PMID:8702617 PMID:9843699 RGD:1601497 RGD:8554308 NCBI chrNW_004936518:8,093,111...8,158,862 JBrowse link
G Oxtr oxytocin receptor ISO RGD PMID:15821089 RGD:1579892 NCBI chrNW_004936602:4,241,743...4,259,866 JBrowse link
G Prlhr prolactin releasing hormone receptor ISO RGD PMID:15854142 RGD:1641829 NCBI chrNW_004936486:8,177,111...8,181,663 JBrowse link
G Prlr prolactin receptor ISO (PMID:7984244) BHF-UCL PMID:7984244 NCBI chrNW_004936518:6,352,133...6,495,242 JBrowse link
G Pth1r parathyroid hormone 1 receptor ISO PMID:19608645
(PMID:19674967)
BHF-UCL
UniProtKB
RGD
PMID:9054374 PMID:9642250 PMID:19608645 PMID:19674967 RGD:7207454 RGD:7207455 RGD:8553376 NCBI chrNW_004936596:674,088...693,191 JBrowse link
G Rxfp2 relaxin family peptide receptor 2 ISO RGD PMID:15956681 RGD:1600172 NCBI chrNW_004936472:26,425,829...26,487,700 JBrowse link
G Sctr secretin receptor ISO (PMID:7612008) GO_Central PMID:7612008 NCBI chrNW_004936469:50,851,569...50,916,183 JBrowse link
G Slc40a1 solute carrier family 40 member 1 ISO (PMID:22682227)
(MGI:3521561|PMID:15514116)
BHF-UCL PMID:15514116 PMID:22682227 MGI:3521561 NCBI chrNW_004936506:8,396,593...8,415,069 JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO (PMID:8390245) GO_Central PMID:8390245 NCBI chrNW_004936695:2,564,917...2,597,009 JBrowse link
steroid hormone binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO (PMID:14742675) BHF-UCL PMID:14742675 NCBI chrNW_004936627:1,555,151...1,584,370 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO (PMID:19931550) UniProtKB PMID:19931550 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G LOC101966570 sodium/potassium-transporting ATPase subunit alpha-2 ISO PMID:17442282
(PMID:14742675)
BHF-UCL PMID:14742675 PMID:17442282 RGD:6903343 NCBI chrNW_004936740:489,357...514,235 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO (PMID:17635946) UniProtKB PMID:17635946 NCBI chrNW_004936504:10,960,069...11,056,834 JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 ISO (PMID:12923182) CAFA PMID:12923182 NCBI chrNW_004936664:2,626,810...2,655,290 JBrowse link
thyroid hormone binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 ISO (MGI:3692370|PMID:16241904) MGI PMID:16241904 MGI:3692370 NCBI chrNW_004936483:2,930,781...2,967,309 JBrowse link
G Crym crystallin mu ISO (PMID:16740909)
(PMID:9328354)
UniProtKB PMID:9328354 PMID:16740909 NCBI chrNW_004936501:6,441,968...6,457,814 JBrowse link
G Ctsh cathepsin H ISO (PMID:21217776) UniProtKB PMID:21217776 NCBI chrNW_004936471:37,135,200...37,156,081 JBrowse link
G Pkm pyruvate kinase M1/2 ISO PMID:1883388 CAFA PMID:1883388 RGD:12793012 NCBI chrNW_004936471:31,589,322...31,617,891 JBrowse link
G Thra thyroid hormone receptor alpha ISO (PMID:15466465), (PMID:8710870)
(PMID:2879243)
UniProtKB
MGI
PMID:2879243 PMID:8710870 PMID:15466465 NCBI chrNW_004936490:15,188,341...15,206,032 JBrowse link
G Thrb thyroid hormone receptor beta ISO (PMID:15466465) UniProtKB PMID:15466465 NCBI chrNW_004936473:15,766,214...15,986,389 JBrowse link
G Ttr transthyretin ISO (PMID:21147258) AgBase PMID:21147258 NCBI chrNW_004936682:1,628,489...1,635,495 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14080
    binding 13352
      hormone binding 82
        abscisic acid binding 0
        adiponectin binding 3
        androgen binding 2
        auxin binding 0
        choriogonadotropin hormone binding 1
        cytokinin binding 0
        ecdysone binding 0
        epidermal growth factor binding 3
        estrogen binding 0
        gibberellin binding 0
        juvenile hormone binding 0
        peptide hormone binding + 46
        steroid hormone binding + 5
        thyroid hormone binding 7
paths to the root