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ONTOLOGY REPORT - ANNOTATIONS


Term:pteridine-containing compound biosynthetic process
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Accession:GO:0042559 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
Synonyms:exact_synonym: pteridine and derivative biosynthesis;   pteridine and derivative biosynthetic process;   pteridine-containing compound anabolism;   pteridine-containing compound biosynthesis;   pteridine-containing compound formation;   pteridine-containing compound synthesis
 narrow_synonym: pterin biosynthesis;   pterin biosynthetic process


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pteridine-containing compound biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 ISO (PMID:15721862), (PMID:2463916), (PMID:3753653) RGD PMID:2463916, PMID:3753653, PMID:15721862 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (MGI:MGI:5503248|PMID:23704330)
(PMID:1881876)
RGD PMID:1881876, PMID:23704330 MGI:MGI:5503248 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like ISO (PMID:12937168) RGD PMID:12937168 NCBI chr 1:40,529,092...40,719,232
Ensembl chr 1:40,529,045...40,719,391
JBrowse link
7,8-dihydroneopterin 3'-triphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:11,717,667...11,729,694
Ensembl chr 3:11,717,667...11,723,327
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:96,564,877...96,614,386
Ensembl chr 8:96,564,877...96,614,348
JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase ISO (PMID:23707606)
(MGI:MGI:5645206|PMID:19666465)
RGD PMID:19666465, PMID:23707606 MGI:MGI:5645206 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Gch1 GTP cyclohydrolase 1 TAS
IBA
ISO
PMID:21873635
(PMID:17101830), (PMID:19666465), (PMID:7678411), (PMID:9445252)
RGD PMID:7678411, PMID:9445252, PMID:17101830, PMID:19666465, PMID:12051753, PMID:21873635 RGD:625450, RGD:13792537 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:30,689,690...30,696,465
Ensembl chr20:30,690,810...30,696,476
JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:8,929,675...8,980,712
Ensembl chr17:8,929,810...8,980,571
JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase TAS
IEA
ISO
GO_REF:0000041
(MGI:MGI:1328867|PMID:9894812)
UniProt
RGD
PMID:9894812, PMID:1939130 GO_REF:0000041, MGI:MGI:1328867, RGD:68294 NCBI chr 8:54,954,261...54,961,271
Ensembl chr 8:54,954,226...54,961,265
JBrowse link
G Qdpr quinoid dihydropteridine reductase TAS
IBA
IMP
IDA
PMID:21873635
PMID:1898002
RGD
GO_Central
UniProt
PMID:3680258, PMID:21873635, PMID:1898002, PMID:9235988, PMID:660556 RGD:729701, RGD:13792537, RGD:8553309, RGD:5128582, RGD:4139903 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284
JBrowse link
G RGD1560795 similar to Sepiapterin reductase (SPR) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:116,933,277...116,936,466
Ensembl chr 4:116,933,341...116,936,066
JBrowse link
G Spr sepiapterin reductase TAS
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:2201030, PMID:21873635, PMID:2179471 RGD:70022, RGD:13792537, RGD:1600056 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 TAS RGD PMID:14729668 RGD:1547843 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:7057182 RGD:2301991 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060
JBrowse link
G Dhfr dihydrofolate reductase IDA
IBA
ISO
IEA
PMID:21873635
(PMID:2303423)
GO_REF:0000041
RGD
UniProt
PMID:2303423, PMID:11502523, PMID:21873635 GO_REF:0000041, RGD:1298877, RGD:13792537 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase IDA RGD PMID:4078017 RGD:2301990 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728
JBrowse link
G Gch1 GTP cyclohydrolase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase ISO
IBA
IEA
(PMID:25164808), (PMID:3619447)
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:3619447, PMID:25164808, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:11,717,667...11,729,694
Ensembl chr 3:11,717,667...11,723,327
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      biosynthetic process 6222
        cellular biosynthetic process 6060
          heterocycle biosynthetic process 3959
            pteridine-containing compound biosynthetic process 15
              7,8-dihydroneopterin 3'-triphosphate biosynthetic process 1
              folic acid-containing compound biosynthetic process + 9
              methanopterin-containing compound biosynthetic process + 0
              pteridine biosynthetic process 0
              tatiopterin biosynthetic process + 0
              tetrahydrobiopterin biosynthetic process 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.