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ONTOLOGY REPORT - ANNOTATIONS


Term:pteridine-containing compound biosynthetic process
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Accession:GO:0042559 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
Synonyms:exact_synonym: pteridine and derivative biosynthesis;   pteridine and derivative biosynthetic process;   pteridine-containing compound anabolism;   pteridine-containing compound biosynthesis;   pteridine-containing compound formation;   pteridine-containing compound synthesis
 narrow_synonym: pterin biosynthesis;   pterin biosynthetic process



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pteridine-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:15721862), (PMID:2463916), (PMID:3753653) RGD PMID:2463916 PMID:3753653 PMID:15721862 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
RGD PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO (PMID:12937168) RGD PMID:12937168 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
JBrowse link
7,8-dihydroneopterin 3'-triphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089
JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO (PMID:23707606)
(MGI:5645206|PMID:19666465)
RGD PMID:19666465 PMID:23707606 MGI:5645206 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in TAS
IBA
ISO
PMID:21873635
(PMID:17101830), (PMID:19666465), (PMID:7678411), (PMID:9445252)
RGD PMID:7678411 PMID:9445252 PMID:17101830 PMID:19666465 PMID:12051753 More... RGD:625450, RGD:13792537 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292
JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:8,845,161...8,896,343 JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase acts_upstream_of_or_within
involved_in
TAS
ISO
IEA
(MGI:1328867|PMID:9894812)
GO_REF:0000041
RGD
UniProt
PMID:9894812 PMID:1939130 GO_REF:0000041 MGI:1328867, RGD:68294 NCBI chr 8:50,870,838...50,877,878
Ensembl chr 8:50,870,841...50,877,869
JBrowse link
G Qdpr quinoid dihydropteridine reductase involved_in TAS
IBA
IMP
IDA
PMID:21873635
PMID:1898002
RGD
GO_Central
UniProt
PMID:3680258 PMID:21873635 PMID:1898002 PMID:9235988 PMID:660556 RGD:729701, RGD:13792537, RGD:8553309, RGD:5128582, RGD:4139903 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G RGD1560795 similar to Sepiapterin reductase (SPR) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:117,689,458...117,693,286
Ensembl chr 4:117,689,458...117,692,891
JBrowse link
G Spr sepiapterin reductase involved_in TAS
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:2201030 PMID:21873635 PMID:2179471 RGD:70022, RGD:13792537, RGD:1600056 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 TAS RGD PMID:14729668 RGD:1547843 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:7057182 RGD:2301991 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:2303423)
UniProt
RGD
PMID:2303423 PMID:11502523 PMID:21873635 GO_REF:0000041, RGD:1298877, RGD:13792537 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase IDA RGD PMID:4078017 RGD:2301990 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000041
(PMID:3619447)
(PMID:25164808)
UniProt
RGD
PMID:3619447 PMID:25164808 PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    metabolic process 11798
      biosynthetic process 6072
        cellular biosynthetic process 5914
          heterocycle biosynthetic process 3803
            pteridine-containing compound biosynthetic process 15
              7,8-dihydroneopterin 3'-triphosphate biosynthetic process 1
              folic acid-containing compound biosynthetic process + 9
              methanopterin-containing compound biosynthetic process + 0
              pteridine biosynthetic process 0
              tatiopterin biosynthetic process + 0
              tetrahydrobiopterin biosynthetic process 8
paths to the root