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ONTOLOGY REPORT - ANNOTATIONS

Term:pteridine-containing compound metabolic process
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Accession:GO:0042558 term browser browse the term
Definition:The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
Synonyms:exact_synonym: pteridine and derivative metabolic process;   pteridine and derivative metabolism;   pteridine-containing compound metabolism
 narrow_synonym: pterin metabolic process;   pterin metabolism
 alt_id: GO:0019721


show annotations for term's descendants           Sort by:
pteridine-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(PMID:23704330) 		RGD PMID:1881876 PMID:23704330 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO
IEA
IBA 		(PMID:12937168)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12937168 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
10-formyltetrahydrofolate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase acts_upstream_of_positive_effect ISO
IEA 		(PMID:19933275), (PMID:21238436)
GO_REF:0000107 		RGD
Ensembl		 PMID:19933275 PMID:21238436 GO_REF:0000107 NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in ISO
IEA
IMP
IDA 		(PMID:19933275)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
(PMID:31624291)
GO_REF:0000117
PMID:10585460
PMID:1848231 		RGD
Ensembl
InterPro
UniProt		 PMID:19933275 PMID:31624291 PMID:10585460 PMID:1848231 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117, RGD:150521656, RGD:632027 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO
IEA 		(PMID:21238436)
GO_REF:0000107
GO_REF:0000117
GO_REF:0000002
GO_REF:0000104
(PMID:33168096) 		RGD
Ensembl
UniProt
InterPro		 PMID:21238436 PMID:33168096 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
10-formyltetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IDA RGD PMID:21163947 RGD:7244288 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
dihydrobiopterin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 IDA RGD PMID:2557335 PMID:8486153 PMID:8702680 RGD:2298653, RGD:2298654, RGD:728623 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
dihydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:8948466 RGD:5144056 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889 		JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IBA
ISO 		GO_REF:0000033
(PMID:2303423), (PMID:23707606) 		GO_Central
RGD		 PMID:2303423 PMID:23707606 PMID:11502523 PMID:3970530 GO_REF:0000033, RGD:1298877, RGD:2300196 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 NOT|involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212 		JBrowse link
folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IDA PMID:1848231 UniProt PMID:1848231 RGD:632027 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO
IEA 		(PMID:33168096)
GO_REF:0000107 		RGD
Ensembl		 PMID:33168096 GO_REF:0000107 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IBA 		PMID:20424322
GO_REF:0000033 		GO_Central PMID:20424322 GO_REF:0000033, RGD:10054082 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Folr1 folate receptor alpha acts_upstream_of_or_within ISO
IEA 		MGI:2383986 (PMID:12854656)
GO_REF:0000107 		RGD
Ensembl		 PMID:12854656 GO_REF:0000107 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISS
ISO 		GO_REF:0000024
(PMID:24074862)
(PMID:11466310) 		UniProt
RGD		 PMID:11466310 PMID:24074862 GO_REF:0000024 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:11278996) RGD PMID:11278996 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase involved_in IEA GO_REF:0000117
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000117 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563 		JBrowse link
folic acid-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folh1 folate hydrolase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:11210180)
GO_REF:0000107 		RGD
Ensembl		 PMID:11210180 GO_REF:0000107 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
G Fpgs folylpolyglutamate synthase involved_in ISO (PMID:3619447) RGD PMID:3619447 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO
IEA 		(PMID:12937168)
GO_REF:0000107 		RGD
Ensembl		 PMID:12937168 GO_REF:0000107 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
pteridine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:119,229,447...119,233,320
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
pteridine-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:15721862), (PMID:2463916), (PMID:3753653) RGD PMID:2463916 PMID:3753653 PMID:15721862 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07068905.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 8:817,915...819,124 JBrowse link
G Dhfr dihydrofolate reductase involved_in ISO (PMID:23707606)
(PMID:19666465), (PMID:21402147) 		RGD PMID:19666465 PMID:21402147 PMID:23707606 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO
IBA
IEA 		(PMID:17101830), (PMID:19666465), (PMID:7678411), (PMID:9445252)
GO_REF:0000033
GO_REF:0000043 		RGD
GO_Central
UniProt		 PMID:7678411 PMID:9445252 PMID:17101830 PMID:19666465 GO_REF:0000033 GO_REF:0000043 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000043
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr20:29,573,362...29,587,181
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000043
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr17:8,850,349...8,902,420
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase acts_upstream_of_or_within
involved_in 		TAS
IEA
ISO 		GO_REF:0000107
GO_REF:0000043
GO_REF:0000002
(PMID:9894812)
GO_REF:0000041 		Ensembl
UniProt
InterPro
RGD		 PMID:9894812 PMID:1939130 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107, RGD:68294 NCBI chr 8:59,767,234...59,774,265
Ensembl chr 8:50,870,841...50,877,869 		JBrowse link
G Qdpr quinoid dihydropteridine reductase involved_in TAS
IBA
IEA
IMP
IDA 		GO_REF:0000033
GO_REF:0000043
PMID:1898002 		GO_Central
UniProt
RGD		 PMID:3680258 PMID:1898002 PMID:9235988 PMID:660556 GO_REF:0000033 GO_REF:0000043, RGD:729701, RGD:8553309, RGD:5128582, RGD:4139903 NCBI chr14:69,882,776...69,896,378
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Spr sepiapterin reductase involved_in TAS
IEA
ISO
IBA
IMP 		GO_REF:0000002
(PMID:23640889)
GO_REF:0000033 		InterPro
RGD
GO_Central		 PMID:23640889 PMID:2201030 PMID:2179471 GO_REF:0000002 GO_REF:0000033, RGD:70022, RGD:1600056 NCBI chr 4:119,229,447...119,233,320
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
G Spr-ps1 sepiapterin reductase, pseudogene 1 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:119,246,947...119,250,774
Ensembl chr 4:117,689,458...117,692,891 		JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in IEA GO_REF:0000043
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr17:8,903,248...8,915,714
Ensembl chr17:8,845,084...8,910,539
Ensembl chr 7:8,845,084...8,910,539 		JBrowse link
tetrahydrobiopterin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 involved_in ISO MGI:1856903 (PMID:19286659), (PMID:7524491) RGD PMID:7524491 PMID:19286659 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase involved_in ISO
IEA 		MGI:2669870 (PMID:11517215)
GO_REF:0000107 		RGD
Ensembl		 PMID:11517215 GO_REF:0000107 NCBI chr 8:59,767,234...59,774,265
Ensembl chr 8:50,870,841...50,877,869 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within
involved_in 		ISO MGI:3757641 (PMID:16532389)
MGI:3528977 (PMID:23647001) 		RGD PMID:16532389 PMID:23647001 NCBI chr 4:119,229,447...119,233,320
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 TAS RGD PMID:14729668 RGD:1547843 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:7057182 RGD:2301991 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889 		JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IEA
ISO
IBA 		GO_REF:0000002
(PMID:360074), (PMID:730776)
GO_REF:0000033
(PMID:2303423)
GO_REF:0000041 		InterPro
RGD
GO_Central
UniProt		 PMID:360074 PMID:730776 PMID:2303423 PMID:11502523 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041, RGD:1298877 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO
IEA 		MGI:2383986 (PMID:10508523)
GO_REF:0000107 		RGD
Ensembl		 PMID:10508523 GO_REF:0000107 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Slc46a1 solute carrier family 46 member 1 involved_in ISO
IEA 		(PMID:17962486)
GO_REF:0000107 		RGD
Ensembl		 PMID:17962486 GO_REF:0000107 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848 		JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in ISO
IEA 		(PMID:7972060)
GO_REF:0000107 		RGD
Ensembl		 PMID:7972060 GO_REF:0000107 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Dhfr dihydrofolate reductase involved_in ISO (PMID:360074) RGD PMID:360074 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528 		JBrowse link
G ENSRNOG00000065410 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 Ensembl chr 2:178,497,468...178,499,169 JBrowse link
G LOC134479019 bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISO
IBA
ISS 		GO_REF:0000041
(PMID:15611115), (PMID:16150419), (PMID:23704330)
GO_REF:0000033
GO_REF:0000024
(PMID:10828945), (PMID:1881876) 		UniProt
RGD
GO_Central		 PMID:1881876 PMID:10828945 PMID:15611115 PMID:16150419 PMID:23704330 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1-ps1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, pseudogene 1 involved_in IEA
ISS
IBA 		GO_REF:0000041
GO_REF:0000024
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:116,195,791...116,198,973 JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in IEA
ISO 		GO_REF:0000041
GO_REF:0000107
MGI:5470152 (PMID:23267094) 		UniProt
Ensembl
RGD		 PMID:23267094 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:2180800 (PMID:12024029), (PMID:16150419), (PMID:19948730) 		GO_Central
Ensembl
RGD		 PMID:12024029 PMID:16150419 PMID:19948730 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IDA
IBA
IEA 		GO_REF:0000033
PMID:24733394
GO_REF:0000041 		GO_Central
UniProt
RGD		 PMID:21163947 PMID:24733394 GO_REF:0000033 GO_REF:0000041, RGD:7244288, RGD:150521648 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEA
ISO
IBA 		GO_REF:0000041
GO_REF:0000107
(PMID:11181567)
GO_REF:0000033
UniProtKB:P53128 (PMID:10551815), (PMID:12673793), (PMID:25736335), (PMID:29891918) 		UniProt
Ensembl
RGD
GO_Central		 PMID:10551815 PMID:11181567 PMID:12673793 PMID:25736335 PMID:29891918 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IEA
ISO 		GO_REF:0000041
GO_REF:0000002
MGI:1277989 (PMID:19513116)
(PMID:24698160) 		UniProt
InterPro
RGD		 PMID:19513116 PMID:24698160 GO_REF:0000002 GO_REF:0000041 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IEA
ISO 		GO_REF:0000041
GO_REF:0000002
GO_REF:0000107
MGI:98299 (PMID:19513116), (PMID:34383924) 		UniProt
InterPro
Ensembl
RGD		 PMID:19513116 PMID:34383924 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Tyms thymidylate synthetase involved_in ISO
IEA 		(PMID:15093541)
GO_REF:0000107
(PMID:22057276) 		RGD
Ensembl		 PMID:15093541 PMID:22057276 GO_REF:0000107 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
tetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO
ISS 		(PMID:12096917), (PMID:21876184)
GO_REF:0000024 		RGD
UniProt		 PMID:12096917 PMID:21876184 GO_REF:0000024 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G ENSRNOG00000065410 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:178,497,468...178,499,169 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 TAS RGD PMID:2186031 RGD:1299513 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in ISO
IEA 		(PMID:8218174)
GO_REF:0000107 		RGD
Ensembl		 PMID:8218174 GO_REF:0000107 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase IDA RGD PMID:11730351 RGD:1601423 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:19738041), (PMID:7766710) RGD PMID:7766710 PMID:19738041 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in IDA
IBA
IMP 		GO_REF:0000033 GO_Central
RGD		 PMID:11730351 PMID:21121936 GO_REF:0000033, RGD:1601423, RGD:7207080 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO
IBA 		(PMID:24698160)
GO_REF:0000033 		RGD
GO_Central		 PMID:24698160 GO_REF:0000033 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO
IEA
IBA 		(PMID:24075985), (PMID:25619277)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:24075985 PMID:25619277 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Tyms thymidylate synthetase IEP 5-formyltetrahydrofolate RGD PMID:7503782 RGD:5133451 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase involved_in IEA
ISO
IBA 		GO_REF:0000041
(PMID:24532667), (PMID:9054377)
GO_REF:0000033
(PMID:3619447), (PMID:8408020)
(PMID:25164808) 		UniProt
RGD
GO_Central		 PMID:3619447 PMID:8408020 PMID:9054377 PMID:24532667 PMID:25164808 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563 		JBrowse link
tetrahydrofolylpolyglutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggh gamma-glutamyl hydrolase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        pteridine-containing compound metabolic process 36
          dihydrobiopterin metabolic process 1
          dihydropteridine metabolic process 0
          folic acid-containing compound metabolic process + 28
          methanopterin-containing compound metabolic process + 0
          pteridine metabolic process + 1
          pteridine-containing compound biosynthetic process + 17
          pteridine-containing compound catabolic process + 5
          tatiopterin metabolic process + 0
          tetrahydrobiopterin metabolic process + 10
paths to the root