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ONTOLOGY REPORT - ANNOTATIONS


Term:pteridine-containing compound metabolic process
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Accession:GO:0042558 term browser browse the term
Definition:The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
Synonyms:exact_synonym: pteridine and derivative metabolic process;   pteridine and derivative metabolism;   pteridine-containing compound metabolism
 narrow_synonym: pterin metabolic process;   pterin metabolism
 alt_id: GO:0019721


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pteridine-containing compound metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 17 66,210,444 66,295,014 RGD:1600115
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:1601535
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC680432 similar to methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase JBrowse link 3 121,490,787 121,493,932 RGD:13792537
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1624291
RGD:13792537
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like JBrowse link 1 40,529,092 40,719,232 RGD:1624291
RGD:13792537
10-formyltetrahydrofolate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 JBrowse link 4 123,516,553 123,564,067 RGD:1600115
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 JBrowse link 7 26,375,866 26,425,838 RGD:1600115
10-formyltetrahydrofolate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like JBrowse link 14 18,640,274 18,721,298 RGD:7244288
7,8-dihydroneopterin 3'-triphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:1600115
dihydrobiopterin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:2298653
RGD:2298654
RGD:728623
dihydrofolate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase JBrowse link 9 78,862,013 78,882,061 RGD:5144056
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:1298877
RGD:13792537
RGD:1624291
RGD:2300196
folic acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mthfs methenyltetrahydrofolate synthetase JBrowse link 8 96,564,877 96,614,386 RGD:1624291
G Pm20d2 peptidase M20 domain containing 2 JBrowse link 5 48,416,005 48,437,054 RGD:13792537
folic acid metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:10054082
RGD:13792537
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Gnmt glycine N-methyltransferase JBrowse link 9 16,565,274 16,568,626 RGD:728472
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 1 37,743,089 37,774,485 RGD:1624291
RGD:1600115
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:13792537
folic acid-containing compound biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fpgs folylpolyglutamate synthase JBrowse link 3 11,717,667 11,729,694 RGD:13792537
G Mthfs methenyltetrahydrofolate synthetase JBrowse link 8 96,564,877 96,614,386 RGD:13792537
folic acid-containing compound metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Folh1 folate hydrolase 1 JBrowse link 1 150,323,768 150,395,415 RGD:1624291
RGD:1600115
G Fpgs folylpolyglutamate synthase JBrowse link 3 11,717,667 11,729,694 RGD:1624291
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like JBrowse link 1 40,529,092 40,719,232 RGD:1624291
pteridine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spr sepiapterin reductase JBrowse link 4 116,912,343 116,916,073 RGD:1624291
pteridine-containing compound biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:1624291
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:1624291
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:625450
RGD:13792537
RGD:1624291
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 JBrowse link 20 30,689,690 30,696,465 RGD:1600115
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 JBrowse link 17 8,929,675 8,980,712 RGD:1600115
G Pts 6-pyruvoyl-tetrahydropterin synthase JBrowse link 8 54,954,261 54,961,271 RGD:68294
RGD:1600115
RGD:1624291
G Qdpr quinoid dihydropteridine reductase JBrowse link 14 70,164,682 70,178,284 RGD:729701
RGD:13792537
RGD:8553309
RGD:5128582
RGD:4139903
G RGD1560795 similar to Sepiapterin reductase (SPR) JBrowse link 4 116,933,277 116,936,466 RGD:13792537
G Spr sepiapterin reductase JBrowse link 4 116,912,343 116,916,073 RGD:70022
RGD:13792537
RGD:1600056
tetrahydrobiopterin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:1601535
G Spr sepiapterin reductase JBrowse link 4 116,912,343 116,916,073 RGD:1624291
tetrahydrofolate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 JBrowse link 4 123,516,553 123,564,067 RGD:1547843
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase JBrowse link 9 78,862,013 78,882,061 RGD:2301991
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:1298877
RGD:13792537
RGD:1624291
RGD:1600115
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase JBrowse link 11 31,780,477 31,805,728 RGD:2301990
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:1600115
tetrahydrofolate interconversion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmgdh dimethylglycine dehydrogenase JBrowse link 2 23,289,376 23,370,360 RGD:7245485
G Ftcd formimidoyltransferase cyclodeaminase JBrowse link 20 12,806,957 12,820,466 RGD:1600115
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1600115
RGD:1624291
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase JBrowse link 4 115,004,433 115,015,965 RGD:13792537
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like JBrowse link 14 18,640,274 18,721,298 RGD:7244288
RGD:13792537
RGD:1600115
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:1600115
RGD:13792537
RGD:1624291
G Mthfs methenyltetrahydrofolate synthetase JBrowse link 8 96,564,877 96,614,386 RGD:1624291
RGD:13792537
G Sardh sarcosine dehydrogenase JBrowse link 3 5,737,203 5,802,153 RGD:7245485
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
RGD:1600115
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:1600115
G Tyms thymidylate synthetase JBrowse link 9 121,918,875 121,931,564 RGD:1624291
tetrahydrofolate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:1600115
RGD:1624291
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1299513
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase JBrowse link 4 115,004,433 115,015,965 RGD:1624291
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:1601423
G Mthfs methenyltetrahydrofolate synthetase JBrowse link 8 96,564,877 96,614,386 RGD:1624291
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 17 66,210,444 66,295,014 RGD:1601423
RGD:7207080
G Pipox pipecolic acid and sarcosine oxidase JBrowse link 10 64,951,986 64,964,865 RGD:1600115
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:1624291
RGD:13792537
G Tyms thymidylate synthetase JBrowse link 9 121,918,875 121,931,564 RGD:5133451
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fpgs folylpolyglutamate synthase JBrowse link 3 11,717,667 11,729,694 RGD:1624291
RGD:13792537
tetrahydrofolylpolyglutamate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ggh gamma-glutamyl hydrolase JBrowse link 5 34,040,258 34,063,369 RGD:13792537

Term paths to the root
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Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      cellular metabolic process 10639
        cellular aromatic compound metabolic process 5503
          pteridine-containing compound metabolic process 35
            dihydrobiopterin metabolic process + 1
            dihydropteridine metabolic process 0
            folic acid-containing compound metabolic process + 28
            methanopterin-containing compound metabolic process + 0
            pteridine metabolic process + 1
            pteridine-containing compound biosynthetic process + 16
            pteridine-containing compound catabolic process + 4
            tatiopterin metabolic process + 0
            tetrahydrobiopterin metabolic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.