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ONTOLOGY REPORT - ANNOTATIONS

Term:benzene-containing compound metabolic process
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Accession:GO:0042537 term browser browse the term
Definition:The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
Synonyms:exact_synonym: benzene and derivative metabolic process;   benzene and derivative metabolism;   benzene-containing compound metabolism


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benzene-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in
acts_upstream_of_or_within		 IDA
IMP
IEA
ISO		 benzo[a]pyrene
GO_REF:0000107
MGI:2154690 (PMID:10051580), (PMID:1910294), (PMID:9367523), (PMID:9377560)		 Ensembl
RGD		 PMID:1910294 PMID:9367523 PMID:9377560 PMID:10051580 PMID:9806168 More... GO_REF:0000107, RGD:7800739, RGD:7829724 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IDA 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) RGD PMID:20345183 RGD:5133728 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
4-chlorobiphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
anthranilate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in ISO
IBA
IEA		 (PMID:11985583)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:11985583 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
biphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP PCB126
Aroclor 1254		 RGD PMID:20356859 PMID:19071209 RGD:4448154, RGD:4768197 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP PCB126 RGD PMID:20356859 RGD:4448154 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP PCB 126, 138, 153, 180 RGD PMID:19464308 RGD:4890403 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 IDA RGD PMID:9310344 RGD:1626420 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP Aroclor 1254 RGD PMID:18502095 RGD:4783624 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP Aroclor 1254 RGD PMID:19071209 RGD:4768197 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP Aroclor 1254 RGD PMID:16938428 RGD:4891899 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP Aroclor 1254 RGD PMID:19071209 RGD:4768197 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
homogentisate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
ISS
IEA		 (PMID:18620547)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18620547 GO_REF:0000024 GO_REF:0000107 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in ISO
IBA
IDA		 (PMID:10672018), (PMID:26752518), (PMID:29208702), (PMID:29429898)
(PMID:26752518)
GO_REF:0000033
(MGI:5780894|PMID:26752518)		 RGD
GO_Central		 PMID:10672018 PMID:26752518 PMID:29208702 PMID:29429898 PMID:26752518 GO_REF:0000033 MGI:5780894, RGD:11342439 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 involved_in ISO
IEA
ISS		 (PMID:19338303)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19338303 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19029248)
(MGI:3835225|PMID:19029248)		 UniProt
RGD		 PMID:19029248 GO_REF:0000024 MGI:3835225 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
L-kynurenine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kyat1 kynurenine aminotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
L-kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase IDA RGD PMID:23690293 RGD:13513904 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 IDA RGD PMID:7796908 RGD:9685040 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
mandelate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hao2 hydroxyacid oxidase 2 IDA RGD PMID:8508789 RGD:70759 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
nitrobenzene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:2034681), (PMID:8373352) RGD PMID:2034681 PMID:8373352 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 acts_upstream_of_or_within ISO (PMID:12069689) RGD PMID:12069689 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
phthalate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 IEP di-(2-ethylhexyl)phthalate RGD PMID:16400681 RGD:5133250 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP di(n-butyl) phthalate RGD PMID:18923996 RGD:2317622 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:16809437 RGD:1601046 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP di-(2-ethylhexyl) phthalate RGD PMID:20920559 RGD:4890045 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:20954080 RGD:4891498 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:16809437 RGD:1601046 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Th tyrosine hydroxylase IEP mono-(2-ethylhexyl) phthalate RGD PMID:21145954 RGD:5128805 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
stilbene catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx2 epoxide hydrolase 2 involved_in ISO
IEA		 (PMID:8342951)
GO_REF:0000107		 RGD
Ensembl		 PMID:8342951 GO_REF:0000107 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
toluene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:19110042 RGD:4766784 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000041
(PMID:15866519)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15866519 GO_REF:0000033 GO_REF:0000041 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
IBA		 GO_REF:0000104
(PMID:11751753), (PMID:2419335)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:2419335 PMID:11751753 PMID:10719243 PMID:11513477 GO_REF:0000033 GO_REF:0000104, RGD:2290190, RGD:2290543 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:17671174)
GO_REF:0000104
(PMID:17499941), (PMID:17671174)
GO_REF:0000033
GO_REF:0000041		 RGD
UniProt
GO_Central		 PMID:17499941 PMID:17671174 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kynu kynureninase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27762317)
GO_REF:0000041		 UniProt
RGD		 PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        benzene-containing compound metabolic process 36
          (+)-pinoresinol metabolic process + 0
          (-)-pinoresinol metabolic process + 0
          1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process + 0
          1,2,4-trichlorobenzene catabolic process 0
          1,4-dichlorobenzene catabolic process 0
          1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process + 0
          2,4,5-trichlorophenoxyacetic acid metabolic process + 0
          2,4-dichlorobenzoate metabolic process + 0
          2,4-dichlorophenoxyacetic acid metabolic process + 0
          2-aminobenzenesulfonate metabolic process + 0
          2-chloro-N-isopropylacetanilide metabolic process + 0
          3,4-dihydroxybenzoate metabolic process + 0
          3-chlorocatechol metabolic process + 0
          3-phenylpropionate metabolic process + 0
          4-carboxy-4'-sulfoazobenzene metabolic process 0
          4-chlorobiphenyl metabolic process 1
          4-toluenecarboxylate metabolic process + 0
          anthranilate metabolic process + 3
          benzene metabolic process + 0
          benzoate metabolic process + 0
          benzonitrile metabolic process 0
          biphenyl metabolic process + 10
          bromoxynil metabolic process 0
          chlorobenzene catabolic process 0
          cinnamic acid metabolic process + 0
          ethylbenzene catabolic process + 0
          eugenol metabolic process + 0
          gallate catabolic process + 0
          gerfelin metabolic process + 0
          homogentisate metabolic process + 1
          iprodione metabolic process 0
          kynurenine metabolic process + 9
          mandelate metabolic process + 1
          methylgallate metabolic process + 0
          monodictyphenone metabolic process + 0
          nitrobenzene metabolic process + 5
          o-orsellinic acid metabolic process + 0
          olivetolic acid biosynthetic process 0
          p-cumate metabolic process + 0
          para-aminobenzoic acid metabolic process + 0
          pentachlorophenol metabolic process + 0
          phenylacetate catabolic process 3
          phenylmercury acetate metabolic process + 0
          phthalate metabolic process + 7
          salicylic acid metabolic process + 0
          sinapate metabolic process + 0
          stilbene metabolic process + 1
          styrene metabolic process + 0
          toluene-containing compound metabolic process + 1
          vanillin metabolic process + 0
          xylene metabolic process + 0
paths to the root