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ONTOLOGY REPORT - ANNOTATIONS


Term:benzene-containing compound metabolic process
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Accession:GO:0042537 term browser browse the term
Definition:The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
Synonyms:exact_synonym: benzene and derivative metabolic process;   benzene and derivative metabolism;   benzene-containing compound metabolism


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benzene-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IDA
IMP
benzo[a]pyrene RGD PMID:9806168, PMID:24025706 RGD:7800739, RGD:7829724 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Txnrd1 thioredoxin reductase 1 IDA 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) RGD PMID:20345183 RGD:5133728 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
4-chlorobiphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
anthranilate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase involved_in IBA
ISO
PMID:21873635
(PMID:11985583)
RGD PMID:11985583, PMID:21873635 RGD:13792537 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
biphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP PCB126
Aroclor 1254
RGD PMID:20356859, PMID:19071209 RGD:4448154, RGD:4768197 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP PCB126 RGD PMID:20356859 RGD:4448154 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP PCB 126, 138, 153, 180 RGD PMID:19464308 RGD:4890403 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 IDA RGD PMID:9310344 RGD:1626420 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP Aroclor 1254 RGD PMID:18502095 RGD:4783624 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP Aroclor 1254 RGD PMID:19071209 RGD:4768197
G Srd5a2 steroid 5 alpha-reductase 2 IEP Aroclor 1254 RGD PMID:16938428 RGD:4891899 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein IEP Aroclor 1254 RGD PMID:19071209 RGD:4768197 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
homogentisate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261
JBrowse link
kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
ISS
(PMID:18620547)
GO_REF:0000024
RGD
UniProt
PMID:18620547 GO_REF:0000024 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in ISO
IBA
IDA
(PMID:10672018), (PMID:26752518), (PMID:29208702), (PMID:29429898)
(MGI:5780894|PMID:26752518)
PMID:21873635
RGD PMID:10672018 PMID:26752518 PMID:29208702 PMID:29429898, PMID:21873635, PMID:26752518 MGI:5780894, RGD:13792537, RGD:11342439 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kyat1 kynurenine aminotransferase 1 involved_in ISO
ISS
(PMID:19338303)
GO_REF:0000024
RGD
UniProt
PMID:19338303 GO_REF:0000024 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3835225|PMID:19029248)
UniProt
RGD
PMID:19029248 GO_REF:0000024 MGI:3835225 NCBI chr 2:248,644,473...248,690,289
Ensembl chr 2:248,649,441...248,690,089
JBrowse link
L-kynurenine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kyat1 kynurenine aminotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:248,644,473...248,690,289
Ensembl chr 2:248,649,441...248,690,089
JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
L-kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Kmo kynurenine 3-monooxygenase IDA RGD PMID:23690293 RGD:13513904 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kyat1 kynurenine aminotransferase 1 involved_in IDA
IEA
GO_REF:0000108 GOC PMID:7796908 GO_REF:0000108, RGD:9685040 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
mandelate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hao2 hydroxyacid oxidase 2 IDA RGD PMID:8508789 RGD:70759 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
nitrobenzene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO
IEA
(PMID:2034681), (PMID:8373352)
GO_REF:0000107
RGD
Ensembl
PMID:2034681 PMID:8373352 GO_REF:0000107 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm3 glutathione S-transferase mu 3 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm4 glutathione S-transferase mu 4 acts_upstream_of_or_within ISO (MGI:2387281|PMID:12069689) RGD PMID:12069689 MGI:2387281 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
phthalate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 IEP di-(2-ethylhexyl)phthalate RGD PMID:16400681 RGD:5133250 NCBI chr 5:133,759,722...133,786,452
Ensembl chr 5:133,759,735...133,786,452
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP di(n-butyl) phthalate RGD PMID:18923996 RGD:2317622 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:16809437 RGD:1601046 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP di-(2-ethylhexyl) phthalate RGD PMID:20920559 RGD:4890045 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:20954080 RGD:4891498 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:16809437 RGD:1601046 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Th tyrosine hydroxylase IEP mono-(2-ethylhexyl) phthalate RGD PMID:21145954 RGD:5128805 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
stilbene catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx2 epoxide hydrolase 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:8342951)
Ensembl
RGD
PMID:8342951 GO_REF:0000107 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
toluene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:19110042 RGD:4766784
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3587527|PMID:15866519)
GO_REF:0000041
RGD
UniProt
PMID:15866519, PMID:21873635 GO_REF:0000041 MGI:3587527, RGD:13792537 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
IBA
GO_REF:0000002
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635
InterPro
RGD
PMID:2419335 PMID:11751753, PMID:10719243, PMID:21873635, PMID:11513477 GO_REF:0000002 MGI:2151782 MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
(PMID:17671174)
GO_REF:0000041
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17499941 PMID:17671174, PMID:21873635 GO_REF:0000041 GO_REF:0000107 MGI:3712725 MGI:3719924, RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kynu kynureninase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:27762317)
GO_REF:0000041
UniProt
RGD
PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      cellular metabolic process 10755
        cellular aromatic compound metabolic process 5636
          benzene-containing compound metabolic process 38
            (+)-pinoresinol metabolic process + 0
            (-)-pinoresinol metabolic process + 0
            1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process + 0
            1,2,4-trichlorobenzene metabolic process 0
            1,4-dichlorobenzene metabolic process + 0
            1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process + 0
            2,4,5-trichlorophenoxyacetic acid metabolic process + 0
            2,4-dichlorobenzoate metabolic process + 0
            2,4-dichlorophenoxyacetic acid metabolic process + 0
            2-aminobenzenesulfonate metabolic process + 0
            2-chloro-N-isopropylacetanilide metabolic process + 0
            3,4-dihydroxybenzoate metabolic process + 0
            3-chlorocatechol metabolic process + 0
            3-phenylpropionate metabolic process + 0
            4-carboxy-4'-sulfoazobenzene metabolic process 0
            4-chlorobiphenyl metabolic process 1
            4-toluenecarboxylate metabolic process + 0
            anthranilate metabolic process + 3
            benzene metabolic process + 0
            benzoate metabolic process + 0
            benzonitrile metabolic process 0
            biphenyl metabolic process + 10
            bromoxynil metabolic process 0
            chlorobenzene metabolic process 0
            cinnamic acid metabolic process + 0
            ethylbenzene metabolic process + 0
            eugenol metabolic process + 0
            gallate catabolic process + 0
            gerfelin metabolic process + 0
            homogentisate metabolic process + 1
            iprodione metabolic process 0
            kynurenine metabolic process + 10
            mandelate metabolic process + 1
            methylgallate metabolic process + 0
            monodictyphenone metabolic process + 0
            nitrobenzene metabolic process + 6
            o-orsellinic acid metabolic process + 0
            olivetolic acid biosynthetic process 0
            p-cumate metabolic process + 0
            para-aminobenzoic acid metabolic process + 0
            pentachlorophenol metabolic process + 0
            phenylacetate catabolic process 3
            phenylmercury acetate metabolic process + 0
            phthalate metabolic process + 7
            salicylic acid metabolic process + 0
            sinapate metabolic process + 0
            stilbene metabolic process + 1
            styrene metabolic process + 0
            toluene-containing compound metabolic process + 1
            vanillin metabolic process + 0
            xylene metabolic process + 0
paths to the root