Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:benzene-containing compound metabolic process
go back to main search page
Accession:GO:0042537 term browser browse the term
Definition:The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
Synonyms:exact_synonym: benzene and derivative metabolic process;   benzene and derivative metabolism;   benzene-containing compound metabolism


show annotations for term's descendants           Sort by:
benzene-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IDA
IMP		 benzo[a]pyrene RGD PMID:9806168 PMID:24025706 RGD:7800739, RGD:7829724 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IDA 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) RGD PMID:20345183 RGD:5133728 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
4-chlorobiphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
anthranilate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000104
(PMID:11985583)		 UniProt
RGD		 PMID:11985583 PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
biphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP PCB126
Aroclor 1254		 RGD PMID:20356859 PMID:19071209 RGD:4448154, RGD:4768197 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP PCB126 RGD PMID:20356859 RGD:4448154 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP PCB 126, 138, 153, 180 RGD PMID:19464308 RGD:4890403 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 IDA RGD PMID:9310344 RGD:1626420 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP Aroclor 1254 RGD PMID:18502095 RGD:4783624 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP Aroclor 1254 RGD PMID:19071209 RGD:4768197 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP Aroclor 1254 RGD PMID:16938428 RGD:4891899 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP Aroclor 1254 RGD PMID:19071209 RGD:4768197 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
homogentisate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
ISS		 (PMID:18620547)
GO_REF:0000024		 RGD
UniProt		 PMID:18620547 GO_REF:0000024 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in ISO
IBA
IDA		 (PMID:10672018), (PMID:26752518), (PMID:29208702), (PMID:29429898)
(MGI:5780894|PMID:26752518)
PMID:21873635		 RGD PMID:10672018 PMID:26752518 PMID:29208702 PMID:29429898 PMID:21873635 More... MGI:5780894, RGD:13792537, RGD:11342439 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 involved_in ISO
ISS		 (PMID:19338303)
GO_REF:0000024		 RGD
UniProt		 PMID:19338303 GO_REF:0000024 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3835225|PMID:19029248)		 UniProt
RGD		 PMID:19029248 GO_REF:0000024 MGI:3835225 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
L-kynurenine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kyat1 kynurenine aminotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
L-kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Kmo kynurenine 3-monooxygenase IDA RGD PMID:23690293 RGD:13513904 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 involved_in IDA
IEA		 GO_REF:0000108 GOC
RGD		 PMID:7796908 GO_REF:0000108, RGD:9685040 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
mandelate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hao2 hydroxyacid oxidase 2 IDA RGD PMID:8508789 RGD:70759 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
nitrobenzene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:2034681), (PMID:8373352) RGD PMID:2034681 PMID:8373352 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 acts_upstream_of_or_within ISO (MGI:2387281|PMID:12069689) RGD PMID:12069689 MGI:2387281 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
phthalate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmpk1 cytidine/uridine monophosphate kinase 1 IEP di-(2-ethylhexyl)phthalate RGD PMID:16400681 RGD:5133250 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP di(n-butyl) phthalate RGD PMID:18923996 RGD:2317622 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:16809437 RGD:1601046 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP di-(2-ethylhexyl) phthalate RGD PMID:20920559 RGD:4890045 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:20954080 RGD:4891498 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:16809437 RGD:1601046 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Th tyrosine hydroxylase IEP mono-(2-ethylhexyl) phthalate RGD PMID:21145954 RGD:5128805 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
stilbene catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx2 epoxide hydrolase 2 involved_in ISO
IEA		 (PMID:8342951)
GO_REF:0000107		 RGD
Ensembl		 PMID:8342951 GO_REF:0000107 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
toluene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:19110042 RGD:4766784 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:3587527|PMID:15866519)
GO_REF:0000041		 RGD
UniProt		 PMID:15866519 PMID:21873635 GO_REF:0000041 MGI:3587527, RGD:13792537 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
IBA		 GO_REF:0000107
GO_REF:0000002
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635		 Ensembl
InterPro
RGD		 PMID:2419335 PMID:11751753 PMID:10719243 PMID:21873635 PMID:11513477 GO_REF:0000002 GO_REF:0000107 MGI:2151782 MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000041
GO_REF:0000107
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
(PMID:17671174)		 UniProt
Ensembl
RGD		 PMID:17499941 PMID:17671174 PMID:21873635 GO_REF:0000041 GO_REF:0000107 MGI:3712725 MGI:3719924, RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kynu kynureninase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:27762317)
GO_REF:0000041		 UniProt
RGD		 PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      cellular metabolic process 10142
        cellular aromatic compound metabolic process 5701
          benzene-containing compound metabolic process 37
            (+)-pinoresinol metabolic process + 0
            (-)-pinoresinol metabolic process + 0
            1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process + 0
            1,2,4-trichlorobenzene metabolic process 0
            1,4-dichlorobenzene metabolic process + 0
            1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process + 0
            2,4,5-trichlorophenoxyacetic acid metabolic process + 0
            2,4-dichlorobenzoate metabolic process + 0
            2,4-dichlorophenoxyacetic acid metabolic process + 0
            2-aminobenzenesulfonate metabolic process + 0
            2-chloro-N-isopropylacetanilide metabolic process + 0
            3,4-dihydroxybenzoate metabolic process + 0
            3-chlorocatechol metabolic process + 0
            3-phenylpropionate metabolic process + 0
            4-carboxy-4'-sulfoazobenzene metabolic process 0
            4-chlorobiphenyl metabolic process 1
            4-toluenecarboxylate metabolic process + 0
            anthranilate metabolic process + 3
            benzene metabolic process + 0
            benzoate metabolic process + 0
            benzonitrile metabolic process 0
            biphenyl metabolic process + 10
            bromoxynil metabolic process 0
            chlorobenzene metabolic process 0
            cinnamic acid metabolic process + 0
            ethylbenzene metabolic process + 0
            eugenol metabolic process + 0
            gallate catabolic process + 0
            gerfelin metabolic process + 0
            homogentisate metabolic process + 1
            iprodione metabolic process 0
            kynurenine metabolic process + 10
            mandelate metabolic process + 1
            methylgallate metabolic process + 0
            monodictyphenone metabolic process + 0
            nitrobenzene metabolic process + 5
            o-orsellinic acid metabolic process + 0
            olivetolic acid biosynthetic process 0
            p-cumate metabolic process + 0
            para-aminobenzoic acid metabolic process + 0
            pentachlorophenol metabolic process + 0
            phenylacetate catabolic process 3
            phenylmercury acetate metabolic process + 0
            phthalate metabolic process + 7
            salicylic acid metabolic process + 0
            sinapate metabolic process + 0
            stilbene metabolic process + 1
            styrene metabolic process + 0
            toluene-containing compound metabolic process + 1
            vanillin metabolic process + 0
            xylene metabolic process + 0
paths to the root