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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of tyrosine phosphorylation of STAT protein
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Accession:GO:0042509 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
Synonyms:narrow_synonym: regulation of tyrosine phosphorylation of Stat1 protein;   regulation of tyrosine phosphorylation of Stat2 protein;   regulation of tyrosine phosphorylation of Stat3 protein;   regulation of tyrosine phosphorylation of Stat4 protein;   regulation of tyrosine phosphorylation of Stat5 protein;   regulation of tyrosine phosphorylation of Stat6 protein;   regulation of tyrosine phosphorylation of Stat7 protein
 alt_id: GO:0042510;   GO:0042513;   GO:0042516;   GO:0042519;   GO:0042522;   GO:0042525;   GO:0042528


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regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot7 CCR4-NOT transcription complex subunit 7 involved_in ISO (PMID:23386060) UniProt PMID:23386060 NCBI chrNW_004955463:285,228...306,077
Ensembl chrNW_004955463:285,228...306,077
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:12023369) BHF-UCL PMID:12023369 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 acts_upstream_of_or_within ISO (PMID:12700595) MGI PMID:12700595 NCBI chrNW_004955436:22,208,267...22,219,667
Ensembl chrNW_004955436:22,211,175...22,220,566
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:12023369) BHF-UCL PMID:12023369 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:21606371) MGI PMID:21606371 NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109
JBrowse link
negative regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 acts_upstream_of_or_within ISO (PMID:12388746) MGI PMID:12388746 NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
JBrowse link
G Ggnbp2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (PMID:26764350) MGI PMID:26764350 NCBI chrNW_004955451:1,345,720...1,386,100
Ensembl chrNW_004955451:1,345,626...1,386,099
JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha ISO STAT5b RGD PMID:16584384 RGD:1625011 NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in ISO (PMID:25476455) UniProt PMID:25476455 NCBI chrNW_004955551:634,724...641,266
Ensembl chrNW_004955551:570,304...640,243
JBrowse link
G Irf1 interferon regulatory factor 1 ISO RGD PMID:20980260 RGD:5128774 NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in ISO (PMID:12444102) HGNC-UCL PMID:12444102 NCBI chrNW_004955455:3,862,804...3,950,669
Ensembl chrNW_004955455:3,862,347...3,951,891
JBrowse link
G Parp14 poly(ADP-ribose) polymerase family member 14 involved_in ISO (PMID:27796300) UniProt PMID:27796300 NCBI chrNW_004955427:21,878,980...21,929,097
Ensembl chrNW_004955427:21,879,740...21,927,883
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) UniProt PMID:16393965 NCBI chrNW_004955404:33,713,903...33,897,622
Ensembl chrNW_004955404:33,714,193...33,897,622
JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:12359225)
(MGI:5493214|PMID:17210636)
UniProt PMID:12359225 PMID:17210636 MGI:5493214 NCBI chrNW_004955402:771,410...846,671 JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25019494)
(PMID:9202127)
BHF-UCL
MGI
PMID:9202127 PMID:25019494 NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109
JBrowse link
G Socs3 suppressor of cytokine signaling 3 involved_in ISO (PMID:25019494) BHF-UCL PMID:25019494 NCBI chrNW_004955506:4,222,455...4,225,563
Ensembl chrNW_004955506:4,222,455...4,225,563
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit ISO RGD PMID:23192652 RGD:9586745 NCBI chrNW_004955481:6,867,175...6,917,548
Ensembl chrNW_004955481:6,867,175...6,917,548
JBrowse link
positive regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl2bp ADP ribosylation factor like GTPase 2 binding protein involved_in ISO (PMID:18234692) UniProt PMID:18234692 NCBI chrNW_004955433:14,887,094...14,894,119 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:9417081) BHF-UCL PMID:9417081 NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
JBrowse link
G Cd40 CD40 molecule involved_in ISO (PMID:21410936) BHF-UCL PMID:21410936 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
JBrowse link
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (PMID:10966616), (PMID:11285233)
(MGI:5009184|PMID:12090754)
BHF-UCL PMID:10966616 PMID:11285233 PMID:12090754 MGI:5009184 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628
JBrowse link
G Cntf ciliary neurotrophic factor acts_upstream_of_or_within
involved_in
ISO retinal ganglion cells under increased intraocular pressure
(PMID:15207851)
(PMID:12643274), (PMID:21912637)
RGD
MGI
BHF-UCL
PMID:12643274 PMID:14725620 PMID:15207851 PMID:21912637 RGD:1626115 NCBI chrNW_004955511:3,527,552...3,531,275
Ensembl chrNW_004955511:3,527,552...3,534,348
JBrowse link
G Crlf1 cytokine receptor like factor 1 involved_in ISO (PMID:10966616) BHF-UCL PMID:10966616 NCBI chrNW_004955524:2,998,258...3,003,553
Ensembl chrNW_004955524:2,998,260...3,003,283
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO (MGI:5294320|PMID:8007983) UniProt PMID:8007983 MGI:5294320 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:9722506) BHF-UCL PMID:9722506 NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312
JBrowse link
G Ctf1 cardiotrophin 1 involved_in ISO (PMID:21912637) CACAO PMID:21912637 NCBI chrNW_004955493:7,735,996...7,737,559 JBrowse link
G Epo erythropoietin involved_in ISO (PMID:9722506) BHF-UCL PMID:9722506 NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISO (PMID:16837552)
(MGI:3689173|PMID:16837552)
UniProt PMID:16837552 MGI:3689173 NCBI chrNW_004955457:3,177,905...4,236,152
Ensembl chrNW_004955457:3,177,991...4,228,558
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (PMID:17561467) UniProt PMID:17561467 NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5528626|PMID:23438599) CACAO PMID:23438599 MGI:5528626 NCBI chrNW_004955411:36,403,156...36,597,660
Ensembl chrNW_004955411:36,401,842...36,512,054
JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (MGI:3694161|PMID:10713104) UniProt PMID:10713104 MGI:3694161 NCBI chrNW_004955427:20,999,934...21,020,401
Ensembl chrNW_004955427:20,999,485...21,020,531
JBrowse link
G Hdac1 histone deacetylase 1 ISO RGD PMID:21465537 RGD:9590234 NCBI chrNW_004955452:10,636,366...10,668,873
Ensembl chrNW_004955452:10,636,366...10,670,864
JBrowse link
G Hdac2 histone deacetylase 2 ISO RGD PMID:21465537 RGD:9590234 NCBI chrNW_004955526:2,739,099...2,759,640
Ensembl chrNW_004955526:2,728,377...2,759,707
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in ISO (MGI:5284803|PMID:15156153) UniProt PMID:15156153 MGI:5284803 NCBI chrNW_004955420:14,565,921...14,568,447
Ensembl chrNW_004955420:14,564,283...14,568,447
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO (MGI:5284803|PMID:15156153) UniProt PMID:15156153 MGI:5284803 NCBI chrNW_004955486:8,700,212...8,701,581
Ensembl chrNW_004955486:8,700,162...8,701,748
JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chrNW_004955414:22,158,654...22,169,133
Ensembl chrNW_004955414:22,156,819...22,169,631
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22426029 RGD:10402789 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351
JBrowse link
G Ifng interferon gamma involved_in
acts_upstream_of_or_within
ISO PMID:20624457
(PMID:16280321)
(PMID:15604419)
BHF-UCL
MGI
PMID:15604419 PMID:16280321 PMID:20624457 RGD:8554478 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:9722506) BHF-UCL PMID:9722506 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:12372421) UniProt PMID:12372421 NCBI chrNW_004955448:10,611,131...10,617,911 JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:12023369) BHF-UCL PMID:12023369 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
JBrowse link
G Il13 interleukin 13 ISO RGD PMID:21804025 RGD:5684373 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il15 interleukin 15 ISO RGD PMID:8942753 RGD:5024920 NCBI chrNW_004955471:1,496,352...1,583,919
Ensembl chrNW_004955471:1,497,483...1,511,469
JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:10903731) CACAO PMID:10903731 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
JBrowse link
G Il2 interleukin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:19088061)
(PMID:10485657)
BHF-UCL
MGI
PMID:10485657 PMID:19088061 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:17673207) MGI PMID:17673207 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:12023369), (PMID:19088061) BHF-UCL PMID:12023369 PMID:19088061 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Il24 interleukin 24 ISO RGD PMID:19258414 RGD:5147427 NCBI chrNW_004955406:42,431,845...42,437,392
Ensembl chrNW_004955406:42,432,795...42,437,016
JBrowse link
G Il31ra interleukin 31 receptor A involved_in ISO (PMID:11877449) UniProt PMID:11877449 NCBI chrNW_004955446:11,857,882...11,963,867
Ensembl chrNW_004955446:11,857,862...11,961,147
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
ISO (PMID:12574355)
(PMID:10485657)
ARUK-UCL
MGI
PMID:10485657 PMID:12574355 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:28433754)
(PMID:12643274), (PMID:19390056), (PMID:31886314)
ARUK-UCL
BHF-UCL
PMID:12643274 PMID:19390056 PMID:28433754 PMID:31886314 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Il6r interleukin 6 receptor involved_in ISO (PMID:12643274) BHF-UCL PMID:12643274 NCBI chrNW_004955545:932,814...979,359
Ensembl chrNW_004955545:950,765...981,762
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO (PMID:14764690) BHF-UCL PMID:14764690 NCBI chrNW_004955446:11,790,636...11,837,734
Ensembl chrNW_004955446:11,790,444...11,835,001
JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO (PMID:15659653) MGI PMID:15659653 NCBI chrNW_004955446:15,824,956...15,835,000
Ensembl chrNW_004955446:15,824,035...15,835,046
JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (MGI:3828422|PMID:8923468), (MGI:5284803|PMID:15156153) BHF-UCL PMID:8923468 PMID:15156153 MGI:3828422 MGI:5284803 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:21135090) UniProt PMID:21135090 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:11254359) MGI PMID:11254359 NCBI chrNW_004955452:10,608,317...10,632,310
Ensembl chrNW_004955452:10,608,318...10,632,310
JBrowse link
G Lep leptin ISO RGD PMID:19726711 RGD:5128629 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G Lif LIF interleukin 6 family cytokine involved_in ISO (PMID:20624457) BHF-UCL PMID:20624457 NCBI chrNW_004955455:4,489,515...4,505,439
Ensembl chrNW_004955455:4,489,421...4,497,940
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3694161|PMID:10713104) UniProt PMID:10713104 MGI:3694161 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142
JBrowse link
G Osbp oxysterol binding protein ISO RGD PMID:18230613 RGD:2291921 NCBI chrNW_004955511:4,057,514...4,076,039
Ensembl chrNW_004955511:4,057,514...4,076,046
JBrowse link
G Osm oncostatin M involved_in ISO (PMID:21912637) CACAO PMID:21912637 NCBI chrNW_004955455:4,510,711...4,515,282
Ensembl chrNW_004955455:4,511,769...4,514,633
JBrowse link
G Parp14 poly(ADP-ribose) polymerase family member 14 involved_in ISO (PMID:27796300) UniProt PMID:27796300 NCBI chrNW_004955427:21,878,980...21,929,097
Ensembl chrNW_004955427:21,879,740...21,927,883
JBrowse link
G Parp9 poly(ADP-ribose) polymerase family member 9 involved_in ISO (PMID:27796300) UniProt PMID:27796300 NCBI chrNW_004955427:21,770,158...21,806,091
Ensembl chrNW_004955427:21,770,577...21,804,717
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:11254359) MGI PMID:11254359 NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) UniProt PMID:16393965 NCBI chrNW_004955404:33,713,903...33,897,622
Ensembl chrNW_004955404:33,714,193...33,897,622
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:17067562 RGD:10043389 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
JBrowse link
G Tnf tumor necrosis factor involved_in ISO PMID:29702085 ARUK-UCL PMID:29702085 RGD:13800534 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 involved_in ISO (PMID:23892569) UniProt PMID:23892569 NCBI chrNW_004955486:9,571,527...9,573,733
Ensembl chrNW_004955486:9,571,530...9,573,733
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO (PMID:21410936) BHF-UCL PMID:21410936 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (PMID:23892569) UniProt PMID:23892569 NCBI chrNW_004955406:13,391,162...13,402,479 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      signal transduction 3950
        cell surface receptor signaling pathway 2177
          cell surface receptor signaling pathway via STAT 144
            cell surface receptor signaling pathway via JAK-STAT 134
              tyrosine phosphorylation of STAT protein 66
                regulation of tyrosine phosphorylation of STAT protein 66
                  negative regulation of tyrosine phosphorylation of STAT protein 12
                  positive regulation of tyrosine phosphorylation of STAT protein 54
Path 2
Term Annotations click to browse term
  biological_process 12346
    metabolic process 7467
      organic substance metabolic process 7146
        macromolecule metabolic process 6003
          protein metabolic process 2844
            protein modification process 1553
              peptidyl-amino acid modification 411
                peptidyl-tyrosine modification 202
                  peptidyl-tyrosine phosphorylation 202
                    regulation of peptidyl-tyrosine phosphorylation 196
                      regulation of tyrosine phosphorylation of STAT protein 66
                        negative regulation of tyrosine phosphorylation of STAT protein 12
                        positive regulation of tyrosine phosphorylation of STAT protein 54
paths to the root