Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:gamma-delta T cell differentiation
go back to main search page
Accession:GO:0042492 term browser browse the term
Definition:The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: gamma-delta T lymphocyte differentiation
 related_synonym: gamma-delta T cell development


show annotations for term's descendants           Sort by:
 
gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag2 jagged canonical Notch ligand 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342169|PMID:10383933)
Ensembl
RGD
PMID:10383933 GO_REF:0000107 MGI:1342169 NCBI chr 6:137,711,144...137,733,331
Ensembl chr 6:137,711,155...137,733,026
JBrowse link
G Sox13 SRY-box transcription factor 13 involved_in ISO (MGI:3695974|PMID:17218525), (MGI:6276541|PMID:30413363) RGD PMID:17218525 PMID:30413363 MGI:3695974 MGI:6276541 NCBI chr13:50,434,702...50,479,118
Ensembl chr13:50,434,702...50,479,657
JBrowse link
G Tcf7 transcription factor 7 involved_in ISO (MGI:6276541|PMID:30413363) RGD PMID:30413363 MGI:6276541 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr9 C-C motif chemokine receptor 9 acts_upstream_of_or_within ISO MGI:3654108 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Gpr18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO MGI:5708707 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:18064301) RGD PMID:18064301 NCBI chr 4:163,453,435...163,463,718
Ensembl chr 4:163,458,528...163,463,718
JBrowse link
gamma-delta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Olr292 olfactory receptor 292 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:212,714,092...212,886,388
Ensembl chr 1:212,885,464...212,886,381
JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:11859104 RGD:625608 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO MGI:1857211 (MGI:70338|PMID:7807014) RGD PMID:7807014 MGI:70338 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5486619|PMID:23562159)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23562159 GO_REF:0000024 GO_REF:0000107 MGI:5486619 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(MGI:3818191|PMID:19015308)
UniProt
RGD
PMID:19015308 GO_REF:0000024 MGI:3818191 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (MGI:70338|PMID:7807014) RGD PMID:7807014 MGI:70338 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Sox13 SRY-box transcription factor 13 involved_in ISO (MGI:5486619|PMID:23562159) RGD PMID:23562159 MGI:5486619 NCBI chr13:50,434,702...50,479,118
Ensembl chr13:50,434,702...50,479,657
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:5486619|PMID:23562159) RGD PMID:23562159 MGI:5486619 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (MGI:3054293|PMID:15294943) RGD PMID:15294943 MGI:3054293 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103036 (MGI:3054293|PMID:15294943)
Ensembl
RGD
PMID:15294943 GO_REF:0000107 MGI:3054293 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857421|MGI:2384078 (MGI:77314|PMID:7477352), (MGI:83585|PMID:8790395)
Ensembl
RGD
PMID:7477352 PMID:8790395 GO_REF:0000107 MGI:77314 MGI:83585 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr3 early growth response 3 acts_upstream_of_or_within ISO (MGI:5139961|PMID:21737317) RGD PMID:21737317 MGI:5139961 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Rorc RAR-related orphan receptor C acts_upstream_of_or_within ISO (MGI:5139961|PMID:21737317) RGD PMID:21737317 MGI:5139961 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Sox13 SRY-box transcription factor 13 acts_upstream_of_or_within ISO (MGI:5139961|PMID:21737317) RGD PMID:21737317 MGI:5139961 NCBI chr13:50,434,702...50,479,118
Ensembl chr13:50,434,702...50,479,657
JBrowse link
G Tcf7 transcription factor 7 involved_in ISO (MGI:5486619|PMID:23562159) RGD PMID:23562159 MGI:5486619 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    immune system process 2913
      leukocyte activation 1069
        lymphocyte activation 883
          T cell activation 529
            T cell differentiation 297
              gamma-delta T cell differentiation 18
                gamma-delta T cell differentiation involved in immune response 0
                gamma-delta T cell lineage commitment 1
                gamma-delta intraepithelial T cell differentiation + 3
                negative regulation of gamma-delta T cell differentiation 0
                positive regulation of gamma-delta T cell differentiation 10
                regulation of gamma-delta T cell differentiation + 13
Path 2
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure development 6178
        multicellular organism development 5617
          system development 5288
            immune system development 1092
              hematopoietic or lymphoid organ development 1026
                hemopoiesis 974
                  leukocyte differentiation 609
                    mononuclear cell differentiation 474
                      lymphocyte differentiation 422
                        T cell differentiation 297
                          gamma-delta T cell differentiation 18
                            gamma-delta T cell differentiation involved in immune response 0
                            gamma-delta T cell lineage commitment 1
                            gamma-delta intraepithelial T cell differentiation + 3
                            negative regulation of gamma-delta T cell differentiation 0
                            positive regulation of gamma-delta T cell differentiation 10
                            regulation of gamma-delta T cell differentiation + 13
paths to the root