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ONTOLOGY REPORT - ANNOTATIONS


Term:odontogenesis of dentin-containing tooth
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Accession:GO:0042475 term browser browse the term
Definition:The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
Comment:Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See http://en.wikipedia.org/wiki/Placoid_scale#Placoid_scales.
Synonyms:exact_synonym: odontogenesis of dentine-containing teeth;   odontogenesis of dentine-containing tooth
 broad_synonym: odontogeny;   odontosis;   tooth development
 only_in_taxon: NCBITaxon:7711 ! Chordata


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odontogenesis of dentin-containing tooth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr2b activin receptor IIB JBrowse link 9 119,401,583 119,442,148 RGD:2290270
G Ambn ameloblastin JBrowse link 5 88,455,991 88,468,531 RGD:2290270
G Amelx amelogenin, X-linked JBrowse link X 169,176,114 169,187,209 RGD:2290270
G Amtn amelotin JBrowse link 5 88,376,108 88,385,916 RGD:2290270
G Ankrd11 ankyrin repeat domain 11 JBrowse link 8 122,883,321 123,042,284 RGD:2290270
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:2290270
G Bcl11b B cell leukemia/lymphoma 11B JBrowse link 12 107,910,403 108,004,145 RGD:2290270
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:2290270
G Bmp2 bone morphogenetic protein 2 JBrowse link 2 133,552,159 133,562,896 RGD:2290270
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Bmp7 bone morphogenetic protein 7 JBrowse link 2 172,868,012 172,940,321 RGD:2290270
G Bmpr1a bone morphogenetic protein receptor, type 1A JBrowse link 14 34,411,061 34,503,336 RGD:2290270
G Ccdc154 coiled-coil domain containing 154 JBrowse link 17 25,162,175 25,171,913 RGD:2290270
G Chuk conserved helix-loop-helix ubiquitous kinase JBrowse link 19 44,073,334 44,107,505 RGD:2290270
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:2290270
G Dll1 delta like canonical Notch ligand 1 JBrowse link 17 15,367,354 15,376,927 RGD:2290270
G Dlx1 distal-less homeobox 1 JBrowse link 2 71,528,113 71,533,981 RGD:2290270
G Dlx2 distal-less homeobox 2 JBrowse link 2 71,543,408 71,546,754 RGD:2290270
G Dlx3 distal-less homeobox 3 JBrowse link 11 95,120,117 95,125,296 RGD:2290270
G Eda ectodysplasin-A JBrowse link X 99,975,606 100,400,760 RGD:2290270
G Edar ectodysplasin-A receptor JBrowse link 10 58,600,780 58,675,696 RGD:2290270
G Edaradd EDAR (ectodysplasin-A receptor)-associated death domain JBrowse link 13 12,471,209 12,520,535 RGD:2290270
G Enam enamelin JBrowse link 5 88,487,975 88,506,049 RGD:2290270
G Fgf10 fibroblast growth factor 10 JBrowse link 13 118,714,699 118,792,573 RGD:2290270
G Fgf4 fibroblast growth factor 4 JBrowse link 7 144,861,386 144,865,245 RGD:2290270
G Foxc1 forkhead box C1 JBrowse link 13 31,806,646 31,810,635 RGD:2290270
G Fst follistatin JBrowse link 13 114,452,262 114,458,989 RGD:2290270
G Gli2 GLI-Kruppel family member GLI2 JBrowse link 1 118,834,061 119,054,405 RGD:2290270
G Gli3 GLI-Kruppel family member GLI3 JBrowse link 13 15,463,723 15,730,026 RGD:2290270
G Hand1 heart and neural crest derivatives expressed 1 JBrowse link 11 57,828,713 57,832,147 RGD:2290270
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 8 57,320,983 57,324,517 RGD:2290270
G Hdac1 histone deacetylase 1 JBrowse link 4 129,516,104 129,542,646 RGD:2290270
G Hdac2 histone deacetylase 2 JBrowse link 10 36,974,297 37,001,889 RGD:2290270
G Itga6 integrin alpha 6 JBrowse link 2 71,786,886 71,858,427 RGD:2290270
G Jag2 jagged 2 JBrowse link 12 112,907,803 112,929,812 RGD:2290270
G Lama5 laminin, alpha 5 JBrowse link 2 180,176,373 180,225,904 RGD:2290270
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 3 131,110,277 131,224,357 RGD:2290270
G Lhx8 LIM homeobox protein 8 JBrowse link 3 154,306,288 154,330,560 RGD:2290270
G Lrp4 low density lipoprotein receptor-related protein 4 JBrowse link 2 91,457,456 91,513,901 RGD:2290270
G Lrp6 low density lipoprotein receptor-related protein 6 JBrowse link 6 134,446,476 134,566,913 RGD:2290270
G Msx1 msh homeobox 1 JBrowse link 5 37,820,491 37,824,585 RGD:2290270
G Nf2 neurofibromin 2 JBrowse link 11 4,757,639 4,849,544 RGD:2290270
G Nfic nuclear factor I/C JBrowse link 10 81,396,191 81,431,919 RGD:2290270
G Nkx2-3 NK2 homeobox 3 JBrowse link 19 43,612,325 43,615,892 RGD:2290270
G Odam odontogenic, ameloblast asssociated JBrowse link 5 87,885,010 87,894,809 RGD:2290270
G Pdgfra platelet derived growth factor receptor, alpha polypeptide JBrowse link 5 75,151,322 75,198,206 RGD:2290270
G Rogdi rogdi homolog JBrowse link 16 5,008,729 5,013,574 RGD:2290270
G Runx2 runt related transcription factor 2 JBrowse link 17 44,495,987 44,814,797 RGD:2290270
G Shh sonic hedgehog JBrowse link 5 28,456,840 28,467,101 RGD:2290270
G Smo smoothened, frizzled class receptor JBrowse link 6 29,735,497 29,761,366 RGD:2290270
G Sostdc1 sclerostin domain containing 1 JBrowse link 12 36,314,169 36,318,452 RGD:2290270
G Tbx1 T-box 1 JBrowse link 16 18,581,704 18,590,671 RGD:2290270
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box JBrowse link 19 55,741,797 55,933,659 RGD:2290270
G Traf6 TNF receptor-associated factor 6 JBrowse link 2 101,678,420 101,701,668 RGD:2290270
G Trp63 transformation related protein 63 JBrowse link 16 25,683,763 25,892,088 RGD:2290270
G Wnt6 wingless-type MMTV integration site family, member 6 JBrowse link 1 74,754,342 74,785,322 RGD:2290270
G Wnt7b wingless-type MMTV integration site family, member 7B JBrowse link 15 85,535,437 85,581,821 RGD:2290270
amelogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf2 activating transcription factor 2 JBrowse link 2 73,816,509 73,892,677 RGD:2290270
G Dspp dentin sialophosphoprotein JBrowse link 5 104,170,703 104,180,127 RGD:2290270
G Enam enamelin JBrowse link 5 88,487,975 88,506,049 RGD:2290270
G Itga6 integrin alpha 6 JBrowse link 2 71,786,886 71,858,427 RGD:2290270
G Itgb4 integrin beta 4 JBrowse link 11 115,974,725 116,008,412 RGD:2290270
G Klk4 kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) JBrowse link 7 43,881,160 43,885,804 RGD:2290270
G Klk5 kallikrein related-peptidase 5 JBrowse link 7 43,834,157 43,851,181 RGD:2290270
G Mmp20 matrix metallopeptidase 20 (enamelysin) JBrowse link 9 7,628,231 7,674,968 RGD:2290270
G Perp PERP, TP53 apoptosis effector JBrowse link 10 18,845,071 18,857,073 RGD:2290270
G Relt RELT tumor necrosis factor receptor JBrowse link 7 100,845,847 100,863,489 RGD:2290270
G Slc24a4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 JBrowse link 12 102,128,727 102,267,133 RGD:2290270
dentin mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 JBrowse link 19 3,896,050 3,907,133 RGD:2290270
dentinogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dspp dentin sialophosphoprotein JBrowse link 5 104,170,703 104,180,127 RGD:2290270
G Fam20c family with sequence similarity 20, member C JBrowse link 5 138,755,081 138,810,063 RGD:2290270
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 JBrowse link 5 137,061,504 137,072,272 RGD:2290270
G Smpd3 sphingomyelin phosphodiesterase 3, neutral JBrowse link 8 106,252,548 106,337,965 RGD:2290270
enamel mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnnm4 cyclin M4 JBrowse link 1 36,471,597 36,508,776 RGD:2290270
G Fam20a family with sequence similarity 20, member A JBrowse link 11 109,669,746 109,723,163 RGD:2290270
G Fam20c family with sequence similarity 20, member C JBrowse link 5 138,755,081 138,810,063 RGD:2290270
G Msx2 msh homeobox 2 JBrowse link 13 53,466,881 53,472,780 RGD:2290270
G Nectin1 nectin cell adhesion molecule 1 JBrowse link 9 43,737,075 43,807,461 RGD:2290270
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 15 85,734,910 85,806,851 RGD:2290270
G Stim1 stromal interaction molecule 1 JBrowse link 7 102,261,514 102,437,319 RGD:2290270
G Tbx1 T-box 1 JBrowse link 16 18,581,704 18,590,671 RGD:2290270
G Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 JBrowse link 19 3,896,050 3,907,133 RGD:2290270
G Wdr72 WD repeat domain 72 JBrowse link 9 74,110,331 74,283,203 RGD:2290270
negative regulation of odontogenesis of dentin-containing tooth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rspo2 R-spondin 2 JBrowse link 15 43,020,788 43,171,594 RGD:2290270
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) JBrowse link 15 54,250,619 54,278,484 RGD:2290270
positive regulation of enamel mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amtn amelotin JBrowse link 5 88,376,108 88,385,916 RGD:2290270
G Dspp dentin sialophosphoprotein JBrowse link 5 104,170,703 104,180,127 RGD:2290270
G Enam enamelin JBrowse link 5 88,487,975 88,506,049 RGD:2290270
G Odaph odontogenesis associated phosphoprotein JBrowse link 5 91,987,473 91,995,317 RGD:2290270
positive regulation of odontogenesis of dentin-containing tooth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf1 colony stimulating factor 1 (macrophage) JBrowse link 3 107,741,048 107,760,469 RGD:2290270
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) JBrowse link 11 95,568,818 95,587,698 RGD:2290270
regulation of enamel mineralization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
G Dmp1 dentin matrix protein 1 JBrowse link 5 104,197,575 104,214,102 RGD:2290270
regulation of odontogenesis of dentin-containing tooth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 2 133,552,159 133,562,896 RGD:2290270
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
G Dmrt3 doublesex and mab-3 related transcription factor 3 JBrowse link 19 25,610,246 25,623,921 RGD:2290270
G Fgf8 fibroblast growth factor 8 JBrowse link 19 45,736,798 45,742,941 RGD:2290270
G Ift88 intraflagellar transport 88 JBrowse link 14 57,424,064 57,517,936 RGD:2290270
G Runx2 runt related transcription factor 2 JBrowse link 17 44,495,987 44,814,797 RGD:2290270
G Wnt10a wingless-type MMTV integration site family, member 10A JBrowse link 1 74,792,019 74,804,176 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23015
    developmental process 6306
      anatomical structure morphogenesis 2739
        animal organ morphogenesis 1089
          odontogenesis 119
            odontogenesis of dentin-containing tooth 88
              amelogenesis + 25
              dentin secretion 0
              dentinogenesis + 5
              negative regulation of odontogenesis of dentin-containing tooth + 2
              positive regulation of odontogenesis of dentin-containing tooth + 6
              regulation of odontogenesis of dentin-containing tooth + 17
              tooth placode formation 0
Path 2
Term Annotations click to browse term
  biological_process 23015
    developmental process 6306
      anatomical structure development 5847
        multicellular organism development 5339
          system development 4730
            animal organ development 3480
              animal organ morphogenesis 1089
                odontogenesis 119
                  odontogenesis of dentin-containing tooth 88
                    amelogenesis + 25
                    dentin secretion 0
                    dentinogenesis + 5
                    negative regulation of odontogenesis of dentin-containing tooth + 2
                    positive regulation of odontogenesis of dentin-containing tooth + 6
                    regulation of odontogenesis of dentin-containing tooth + 17
                    tooth placode formation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.