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ONTOLOGY REPORT - ANNOTATIONS

Term:middle ear morphogenesis
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Accession:GO:0042474 term browser browse the term
Definition:The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).


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middle ear morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 acts_upstream_of_or_within ISO MGI:1857637 (MGI:65725|PMID:8152482) RGD PMID:8152482 MGI:65725 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:2687362 (MGI:3847842|PMID:19185569) RGD PMID:19185569 MGI:3847842 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:3785162 (MGI:6100817|PMID:27959908) RGD PMID:27959908 MGI:6100817 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:2150426 (MGI:1344210|PMID:10471511) RGD PMID:10471511 MGI:1344210 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 acts_upstream_of_or_within ISO MGI:3775095 (MGI:3774741|PMID:18219393) RGD PMID:18219393 MGI:3774741 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:3574787 (MGI:3527944|PMID:15630379) RGD PMID:15630379 MGI:3527944 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO MGI:2388397 (MGI:3713422|PMID:17525797) RGD PMID:17525797 MGI:3713422 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gsc goosecoid homeobox involved_in ISO (MGI:3035838|PMID:14973294) RGD PMID:14973294 MGI:3035838 NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
G Hoxa2 homeobox A2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:102778|MGI:1857530|MGI:2385711 (MGI:3525808|PMID:15634706), (MGI:3587518|PMID:15861402), (MGI:3608156|PMID:16221728)
GO_REF:0000107		 RGD
Ensembl		 PMID:15634706 PMID:15861402 PMID:16221728 GO_REF:0000107 MGI:3525808 MGI:3587518 MGI:3608156 Ensembl chr 4:81,262,768...81,265,044 JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (MGI:3689278|PMID:16955138) RGD PMID:16955138 MGI:3689278 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (MGI:3689278|PMID:16955138) RGD PMID:16955138 MGI:3689278 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within ISO MGI:1933766 (MGI:3611627|PMID:16330189) RGD PMID:16330189 MGI:3611627 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2178233|MGI:2386570 (MGI:3712581|PMID:17523175) RGD PMID:17523175 MGI:3712581 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:3769195|PMID:17712420) RGD PMID:17712420 MGI:3769195 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nkx3-2 NK3 homeobox 2 acts_upstream_of_or_within ISO MGI:1931319 (MGI:3035838|PMID:14973294) RGD PMID:14973294 MGI:3035838 NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061 		JBrowse link
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
(PMID:10080184)		 Ensembl
RGD		 PMID:10080184 GO_REF:0000107 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q91ZD1 (MGI:3848564|PMID:19389375)		 UniProt
RGD		 PMID:19389375 GO_REF:0000024 MGI:3848564 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3848564|PMID:19389375)		 UniProt
RGD		 PMID:19389375 GO_REF:0000024 MGI:3848564 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224 		JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3626341 (MGI:3623660|PMID:16571658)		 Ensembl
RGD		 PMID:16571658 GO_REF:0000107 MGI:3623660 NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347 		JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of_or_within ISO MGI:1857640|MGI:98218 (MGI:1306737|PMID:9729491), (MGI:73363|PMID:7758948) RGD PMID:7758948 PMID:9729491 MGI:1306737 MGI:73363 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866 		JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of_or_within ISO MGI:97712 (MGI:1306737|PMID:9729491) RGD PMID:9729491 MGI:1306737 NCBI chr 3:14,132,511...14,168,535
Ensembl chr 3:14,094,004...14,168,535 		JBrowse link
G Rpl38 ribosomal protein L38 acts_upstream_of_or_within ISO MGI:1861228 (MGI:4888466|PMID:21062742) RGD PMID:21062742 MGI:4888466 NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004 		JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:2655195 (MGI:2671031|PMID:12874121) RGD PMID:12874121 MGI:2671031 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Six2 SIX homeobox 2 acts_upstream_of_or_within ISO MGI:96174 (MGI:3525808|PMID:15634706) RGD PMID:15634706 MGI:3525808 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1932522|MGI:2179190|MGI:2179191|MGI:3619149 (MGI:3530686|PMID:15652707), (MGI:3629255|PMID:16600992), (MGI:4822099|PMID:20501333)		 UniProt
RGD		 PMID:15652707 PMID:16600992 PMID:20501333 GO_REF:0000024 MGI:3530686 MGI:3629255 MGI:4822099 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 acts_upstream_of_or_within ISO MGI:3721421 (MGI:3720547|PMID:17586487) RGD PMID:17586487 MGI:3720547 NCBI chr18:77,376,399...77,452,315
Ensembl chr18:77,377,394...77,453,509 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    developmental process 6867
      anatomical structure morphogenesis 2940
        embryonic morphogenesis 697
          middle ear morphogenesis 26
Path 2
Term Annotations click to browse term
  biological_process 19738
    developmental process 6867
      anatomical structure development 6387
        multicellular organism development 5151
          embryo development 1346
            embryonic organ development 555
              embryonic organ morphogenesis 336
                ear morphogenesis 147
                  middle ear morphogenesis 26
paths to the root